Interpretable High-Dimensional Inference Via Score Projection With an Application in Neuroimaging
通过得分投影实现可解释的高维推断:神经影像应用
In the fields of neuroimaging and genetics, a key goal is testing the association of a single outcome with a very high-dimensional imaging or genetic variable. Often, summary measures of the high-dimensional variable are created to sequentially test and localize the association with the outcome. In some cases, the associations between the outcome and summary measures are significant, but subsequent tests used to localize differences are underpowered and do not identify…