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GEE-Assisted Variable Selection for Latent Variable Models with Multivariate Binary Data

多元二元数据潜变量模型的GEE辅助变量选择

Multivariate data are commonly analyzed using one of two approaches: a conditional approach based on generalized linear latent variable models (GLLVMs) or some variation thereof, and a marginal approach based on generalized estimating equations (GEEs). With research on mixed models and GEEs having gone down separate paths, there is a common mindset to treat the two approaches as mutually exclusive, with which to use driven by the question of interest. In this article,…

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Semiparametric Regression Using Variational Approximations

使用变分近似的半参数回归

Semiparametric regression offers a flexible framework for modeling nonlinear relationships between a response and covariates. A prime example are generalized additive models (GAMs) where splines (say) are used to approximate nonlinear functional components in conjunction with a quadratic penalty to control for overfitting. Estimation and inference are then generally performed based on the penalized likelihood, or under a mixed model framework. The penalized likelihood…

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Sparse Pairwise Likelihood Estimation for Multivariate Longitudinal Mixed Models

多元纵向混合模型的稀疏成对似然估计

It is becoming increasingly common in longitudinal studies to collect and analyze data on multiple responses. For example, in the social sciences we may be interested in uncovering the factors driving mental health of individuals over time, where mental health is measured using a set of questionnaire items. One approach to analyzing such multi-dimensional data is multivariate mixed models, an extension of the standard univariate mixed model to handle multiple responses.…

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Joint Selection in Mixed Models using Regularized PQL

利用正则化 PQL 联合选择混合模型效应

The application of generalized linear mixed models presents some major challenges for both estimation, due to the intractable marginal likelihood, and model selection, as we usually want to jointly select over both fixed and random effects. We propose to overcome these challenges by combining penalized quasi-likelihood (PQL) estimation with sparsity inducing penalties on the fixed and random coefficients. The resulting approach, referred to as regularized PQL, is a…

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Outlier Robust Model Selection in Linear Regression

线性回归中对离群值稳健的模型选择

We propose a new approach to the selection of regression models based on combining a robust penalized criterion and a robust conditional expected prediction loss function that is estimated using a stratified bootstrap. Both components of the procedure use robust criteria (i.e., robust ρ-functions) rather than squared error loss to reduce the effects of large residuals and poor bootstrap samples. A key idea is to separate estimation from model selection by choosing estimators…

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