Some Statistical Problems in the Assessment of Inhomogeneities of DNA Sequence Data
DNA序列异质性评估中的若干统计问题
The fields of molecular genetics and medicine are accumulating DNA and protein sequence data at an accelerating rate. Discovering and interpreting sequence patterns can contribute to understanding molecular mechanisms and evolutionary processes. This article considers two types of statistical problems in these contexts: (1) identifying anomalies in the distribution of a specified biochemical marker along a DNA string; in particular, new statistical methods are set forth by…