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重复半连续数据中长期趋势密度的非参数估计AI 解读

We consider nonparametric estimation of the density of the long-term trend of a semicontinuous variable observed repeatedly over time. These variables arise when measuring the intensity of an intermittent phenomenon, such as the intake of an episodically consumed nutrient or the concentration of an intermittent toxic substance: when the phenomenon is absent, the measurement is equal to zero; otherwise, it is positive. Semicontinuous data are usually represented by a two-part…

具有递增半参数单指标交互项的预测型函数线性模型AI 解读

When predicting crop yield using both functional and multivariate predictors, the prediction performances benefit from the inclusion of the interactions between the two sets of predictors. We assume the interaction depends on a nonparametric, single-index structure of the multivariate predictor and reduce each functional predictor’s dimension using functional principal component analysis (FPCA). Allowing the number of FPCA scores to diverge to infinity, we consider a…

S 形函数的非参数免调参估计AI 解读

Abstract We consider the nonparametric estimation of an S-shaped regression function. The least squares estimator provides a very natural, tuning-free approach, but results in a non-convex optimization problem, since the inflection point is unknown. We show that the estimator may nevertheless be regarded as a projection onto a finite union of convex cones, which allows us to propose a mixed primal-dual bases algorithm for its efficient, sequential computation. After…

存在测量误差的间歇性食物摄入分布的半参数估计AI 解读

Dietary data collected from 24-hour dietary recalls are observed with significant measurement errors. In the nonparametric curve estimation literature, much of the effort has been devoted to designing methods that are consistent under contamination by noise, and which have been traditionally applied for analyzing those data. However, some foods such as alcohol or fruits are consumed only episodically, and may not be consumed during the day when the 24-hour recall is…

营养流行病学零膨胀数据的贝叶斯 Copula 密度反卷积AI 解读

Estimating the marginal and joint densities of the long-term average intakes of different dietary components is an important problem in nutritional epidemiology. Since these variables cannot be directly measured, data are usually collected in the form of 24-hour recalls of the intakes, which show marked patterns of conditional heteroscedasticity. Significantly compounding the challenges, the recalls for episodically consumed dietary components also include exact zeros. The…

参数维度增长下的简约模型平均AI 解读

Model averaging generally provides better predictions than model selection, but the existing model averaging methods cannot lead to parsimonious models. Parsimony is an especially important property when the number of parameters is large. To achieve a parsimonious model averaging coefficient estimator, we suggest a novel criterion for choosing weights. Asymptotic properties are derived in two practical scenarios: (i) one or more correct models exist in the candidate model…

MALMEM：线性测量误差模型中的模型平均AI 解读

Summary We develop model averaging estimation in the linear regression model where some covariates are subject to measurement error. The absence of the true covariates in this framework makes the calculation of the standard residual-based loss function impossible. We take advantage of the explicit form of the parameter estimators and construct a weight choice criterion. It is asymptotically equivalent to the unknown model average estimator minimizing the loss function. When…

基于稀疏充分降维的稳健高效因果推断AI 解读

A fundamental assumption used in causal inference with observational data is that treatment assignment is ignorable given measured confounding variables. This assumption of no missing confounders is plausible if a large number of baseline covariates are included in the analysis, as we often have no prior knowledge of which variables can be important confounders. Thus, estimation of treatment effects with a large number of covariates has received considerable attention in…

高维均值相等性的高功效贝叶斯检验AI 解读

We develop a Bayes factor-based testing procedure for comparing two population means in high-dimensional settings. In ‘large-p-small-n” settings, Bayes factors based on proper priors require eliciting a large and complex p × p covariance matrix, whereas Bayes factors based on Jeffrey’s prior suffer the same impediment as the classical Hotelling T2 test statistic as they involve inversion of ill-formed sample covariance matrices. To circumvent this limitation, we propose that…

病例对照研究次要结局分位数回归的半参数有效估计AI 解读

Summary Analysing secondary outcomes is a common practice for case–control studies. Traditional secondary analysis employs either completely parametric models or conditional mean regression models to link the secondary outcome to covariates. In many situations, quantile regression models complement mean-based analyses and provide alternative new insights on the associations of interest. For example, biomedical outcomes are often highly asymmetric, and median regression is…

贝叶斯半参数多元密度反卷积AI 解读

We consider the problem of multivariate density deconvolution when interest lies in estimating the distribution of a vector valued random variable X but precise measurements on X are not available, observations being contaminated by measurement errors U. The existing sparse literature on the problem assumes the density of the measurement errors to be completely known. We propose robust Bayesian semiparametric multivariate deconvolution approaches when the measurement error…

PLEMT：广义指数倾斜混合模型的拟似然 EM 同质性检验AI 解读

Motivated by analyses of DNA methylation data, we propose a semiparametric mixture model, namely the generalized exponential tilt mixture model, to account for heterogeneity between differentially methylated and non-differentially methylated subjects in the cancer group, and capture the differences in higher order moments (e.g. mean and variance) between subjects in cancer and normal groups. A pairwise pseudolikelihood is constructed to eliminate the unknown nuisance…

跨人群的半参数单指数风险评分AI 解读

We consider a problem motivated by issues in nutritional epidemiology, across diseases and populations. In this area, it is becoming increasingly common for diseases to be modeled by a single diet score, such as the Healthy Eating Index, the Mediterranean Diet Score, etc. For each disease and for each population, a partially linear single-index model is fit. The partially linear aspect of the problem is allowed to differ in each population and disease. However, and…

协变量含测量误差时的线性模型选择AI 解读

Prediction precision is arguably the most relevant criterion of a model in practice and is often a sought after property. A common difficulty with covariates measured with errors is the impossibility of performing prediction evaluation on the data even if a model is completely given without any unknown parameters. We bypass this inherent difficulty by using special properties on moment relations in linear regression models with measurement errors. The end product is a model…

高维数据整合AI 解读

Summary We consider situations where the data consist of a number of responses for each individual, which may include a mix of discrete and continuous variables. The data also include a class of predictors, where the same predictor may have different physical measurements across different experiments depending on how the predictor is measured. The goal is to select which predictors affect any of the responses, where the number of such informative predictors tends to infinity…

含测量误差协变量的生存治愈模型：模拟外推推断AI 解读

In many situations in survival analysis, it may happen that a fraction of individuals will never experience the event of interest: they are considered to be cured. The promotion time cure model takes this into account. We consider the case where one or more explanatory variables in the model are subject to measurement error, which should be taken into account to avoid biased estimators. A general approach is the simulation-extrapolation algorithm, a method based on…

利用外部大数据汇总信息校准模型的约束最大似然估计AI 解读

Information from various public and private data sources of extremely large sample sizes are now increasingly available for research purposes. Statistical methods are needed for utilizing information from such big data sources while analyzing data from individual studies that may collect more detailed information required for addressing specific hypotheses of interest. In this article, we consider the problem of building regression models based on individual-level data from…

病例对照研究二次分析中的半参数估计AI 解读

Summary We study the regression relationship between covariates in case–control data: an area known as the secondary analysis of case–control studies. The context is such that only the form of the regression mean is specified, so that we allow an arbitrary regression error distribution, which can depend on the covariates and thus can be heteroscedastic. Under mild regularity conditions we establish the theoretical identifiability of such models. Previous work in this context…

高维协变量非线性交互的广义加性系数模型估计与推断AI 解读

In the low-dimensional case, the generalized additive coefficient model (GACM) proposed by Xue and Yang [Statist. Sinica 16 (2006) 1423–1446] has been demonstrated to be a powerful tool for studying nonlinear interaction effects of variables. In this paper, we propose estimation and inference procedures for the GACM when the dimension of the variables is high. Specifically, we propose a groupwise penalization based procedure to distinguish significant covariates for the…

高维均值相等的两样本检验AI 解读

We develop a test statistic for testing the equality of two population mean vectors in the “large-p-small-n” setting. Such a test must surmount the rank-deficiency of the sample covariance matrix, which breaks down the classic Hotelling T2 test. The proposed procedure, called the generalized component test, avoids full estimation of the covariance matrix by assuming that the p components admit a logical ordering such that the dependence between components is related to their…

协变量同时含测量误差与误分类时的函数型和结构型方法AI 解读

Covariate measurement imprecision or errors arise frequently in many areas. It is well known that ignoring such errors can substantially degrade the quality of inference or even yield erroneous results. Although in practice both covariates subject to measurement error and covariates subject to misclassification can occur, research attention in the literature has mainly focused on addressing either one of these problems separately. To fill this gap, we develop estimation and…

方差函数的部分线性单指标模型AI 解读

Summary We consider heteroscedastic regression models where the mean function is a partially linear single-index model and the variance function depends on a generalized partially linear single-index model. We do not insist that the variance function depends only on the mean function, as happens in the classical generalized partially linear single-index model. We develop efficient and practical estimation methods for the variance function and for the mean function.…

构造函数型数据分类器时离散数据平滑带宽的意外性质AI 解读

The data functions that are studied in the course of functional data analysis are assembled from discrete data, and the level of smoothing that is used is generally that which is appropriate for accurate approximation of the conceptually smooth functions that were not actually observed. Existing literature shows that this approach is effective, and even optimal, when using functional data methods for prediction or hypothesis testing. However, in the present paper we show…

函数型数据中主成分数量的选择AI 解读

Functional principal component analysis (FPCA) has become the most widely used dimension reduction tool for functional data analysis. We consider functional data measured at random, subject-specific time points, contaminated with measurement error, allowing for both sparse and dense functional data, and propose novel information criteria to select the number of principal component in such data. We propose a Bayesian information criterion based on marginal modeling that can…