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Scalable Calibration of Individual-Based Epidemic Models through Categorical Approximations

通过类别分布近似实现个体疫情模型的可扩展校准

Traditional compartmental models capture population-level dynamics but fail to characterize individual-level risk. The computational cost of exact likelihood evaluation for partially observed individual-based models, however, grows exponentially with the population size, necessitating approximate inference. Existing sampling-based methods usually require multiple simulations of the individuals in the population and rely on bespoke proposal distributions or summary…

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Online multivariate changepoint detection: leveraging links with computational geometry

利用计算几何联系进行在线多元变点检测

Abstract The increasing volume of data streams poses significant computational challenges for detecting changepoints online. Likelihood-based methods are effective, but a naive sequential implementation becomes impractical online due to high computational costs. We develop an online algorithm that exactly calculates the likelihood ratio test for a single changepoint in p-dimensional data streams by leveraging a fascinating connection with computational geometry. This…

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High-Dimensional Time Series Segmentation via Factor-Adjusted Vector Autoregressive Modeling

基于因子调整向量自回归的高维时间序列分段

Vector autoregressive (VAR) models are popularly adopted for modelling high-dimensional time series, and their piecewise extensions allow for structural changes in the data. In VAR modelling, the number of parameters grow quadratically with the dimensionality which necessitates the sparsity assumption in high dimensions. However, it is debatable whether such an assumption is adequate for handling datasets exhibiting strong serial and cross-sectional correlations. We propose…

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Authors’ reply to the Discussion of ‘Automatic change-point detection in time series via deep learning’ at the Discussion Meeting on ‘Probabilistic and statistical aspects of machine learning’

关于“通过深度学习自动检测时间序列变点”讨论的作者回复

Detecting change points in data is challenging because of the range of possible types of change and types of behaviour of data when there is no change. Statistically efficient methods for detecting a change will depend on both of these features, and it can be difficult for a practitioner to develop an appropriate detection method for their application of interest. We show how to automatically generate new offline detection methods based on training a neural network. Our…

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Tamás P. Papp, Paul Fearnhead, and Chris Sherlock’s contribution to the Discussion of ‘the Discussion Meeting on Probabilistic and statistical aspects of machine learning’

Papp、Fearnhead 与 Sherlock 对机器学习概率统计讨论会的评论

We provide comments only on the read paper “From Denoising Diffusions to Denoising Markov Models” by Benton, Shi, De Bortoli, Deligiannidis and Doucet. We congratulate the authors on an important contribution to the exciting area of generative models: providing a simple framework for applying the idea of diffusion generative models to data defined on general spaces and for general noising processes. Diffusion models have shown remarkable empirical performance for several…

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Automatic change-point detection in time series via deep learning

基于深度学习的时间序列自动变点检测

Abstract Detecting change points in data is challenging because of the range of possible types of change and types of behaviour of data when there is no change. Statistically efficient methods for detecting a change will depend on both of these features, and it can be difficult for a practitioner to develop an appropriate detection method for their application of interest. We show how to automatically generate new offline detection methods based on training a neural network.…

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Reversible Jump PDMP Samplers for Variable Selection

用于变量选择的可逆跳跃分段确定性马尔可夫过程采样器

A new class of Markov chain Monte Carlo (MCMC) algorithms, based on simulating piecewise deterministic Markov processes (PDMPs), has recently shown great promise: they are nonreversible, can mix better than standard MCMC algorithms, and can use subsampling ideas to speed up computation in big data scenarios. However, current PDMP samplers can only sample from posterior densities that are differentiable almost everywhere, which precludes their use for model choice. Motivated…

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Testing for a Change in Mean after Changepoint Detection

变点检测后的均值变化检验

Abstract While many methods are available to detect structural changes in a time series, few procedures are available to quantify the uncertainty of these estimates post-detection. In this work, we fill this gap by proposing a new framework to test the null hypothesis that there is no change in mean around an estimated changepoint. We further show that it is possible to efficiently carry out this framework in the case of changepoints estimated by binary segmentation and its…

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Stochastic Gradient Markov Chain Monte Carlo

随机梯度马尔可夫链蒙特卡洛

Markov chain Monte Carlo (MCMC) algorithms are generally regarded as the gold standard technique for Bayesian inference. They are theoretically well-understood and conceptually simple to apply in practice. The drawback of MCMC is that performing exact inference generally requires all of the data to be processed at each iteration of the algorithm. For large datasets, the computational cost of MCMC can be prohibitive, which has led to recent developments in scalable Monte…

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Quasi-Stationary Monte Carlo and The Scale Algorithm

准平稳蒙特卡洛与 Scale 算法

Summary This paper introduces a class of Monte Carlo algorithms which are based on the simulation of a Markov process whose quasi-stationary distribution coincides with a distribution of interest. This differs fundamentally from, say, current Markov chain Monte Carlo methods which simulate a Markov chain whose stationary distribution is the target. We show how to approximate distributions of interest by carefully combining sequential Monte Carlo methods with methodology for…

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The Zig-Zag process and super-efficient sampling for Bayesian analysis of big data

Zig-Zag 过程与大数据贝叶斯分析的超高效抽样

Standard MCMC methods can scale poorly to big data settings due to the need to evaluate the likelihood at each iteration. There have been a number of approximate MCMC algorithms that use sub-sampling ideas to reduce this computational burden, but with the drawback that these algorithms no longer target the true posterior distribution. We introduce a new family of Monte Carlo methods based upon a multidimensional version of the Zig-Zag process of [Ann. Appl. Probab. 27 (2017)…

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Changepoint Detection in the Presence of Outliers

存在异常值时的变点检测

Many traditional methods for identifying changepoints can struggle in the presence of outliers, or when the noise is heavy-tailed. Often they will infer additional changepoints to fit the outliers. To overcome this problem, data often needs to be preprocessed to remove outliers, though this is difficult for applications where the data needs to be analyzed online. We present an approach to changepoint detection that is robust to the presence of outliers. The idea is to adapt…

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Convergence of regression-adjusted approximate Bayesian computation

回归调整近似贝叶斯计算的收敛性

We present asymptotic results for the regression-adjusted version of approximate Bayesian computation introduced by Beaumont et al. (2002). We show that for an appropriate choice of the bandwidth, regression adjustment will lead to a posterior that, asymptotically, correctly quantifies uncertainty. Furthermore, for such a choice of bandwidth we can implement an importance sampling algorithm to sample from the posterior whose acceptance probability tends to unity as the data…

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On the asymptotic efficiency of approximate Bayesian computation estimators

近似贝叶斯计算估计量的渐近效率

Many statistical applications involve models for which it is difficult to evaluate the likelihood, but from which it is relatively easy to sample. Approximate Bayesian computation is a likelihood-free method for implementing Bayesian inference in such cases. We present results on the asymptotic variance of estimators obtained using approximate Bayesian computation in a large data limit. Our key assumption is that the data are summarized by a fixed-dimensional summary…

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Particle Metropolis-adjusted Langevin algorithms

粒子 Metropolis 校正 Langevin 算法

In this paper we propose a new sampling scheme based on Langevin dynamics that is applicable in pseudo-marginal and particle Markov chain Monte Carlo algorithms. We investigate the algorithm's theoretical properties under standard asymptotics, which correspond to an increasing dimension |$n$| of the parameters. Our results show that the behaviour of the algorithm depends crucially on how accurately one can estimate the gradient of the log target density. If the error in the…

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Random-Weight Particle Filtering of Continuous Time Processes

Summary It is possible to implement importance sampling, and particle filter algorithms, where the importance sampling weight is random. Such random-weight algorithms have been shown to be efficient for inference for a class of diffusion models, as they enable inference without any (time discretization) approximation of the underlying diffusion model. One difficulty of implementing such random-weight algorithms is the requirement to have weights that are positive with…

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Bayesian Analysis of Isochores

基因组等容区的贝叶斯分析

Statistical identification of isochore structure, the variation in large-scale GC composition (proportion of DNA bases that are G or C as opposed to A or T), of mammalian genomes is a necessary requirement for understanding both the evolution of base composition and the many genomic features such as mutation and recombination rates, which covary with base composition. We have developed a Bayesian method for isochore analysis that we demonstrate to be more accurate than the…

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Particle Filters for Partially Observed Diffusions

部分观测扩散过程的粒子滤波

Summary We introduce a novel particle filter scheme for a class of partially observed multivariate diffusions. We consider a variety of observation schemes, including diffusion observed with error, observation of a subset of the components of the multivariate diffusion and arrival times of a Poisson process whose intensity is a known function of the diffusion (Cox process). Unlike currently available methods, our particle filters do not require approximations of the…

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On-Line Inference for Multiple Changepoint Problems

多重变点问题的在线推断

Summary We propose an on-line algorithm for exact filtering of multiple changepoint problems. This algorithm enables simulation from the true joint posterior distribution of the number and position of the changepoints for a class of changepoint models. The computational cost of this exact algorithm is quadratic in the number of observations. We further show how resampling ideas from particle filters can be used to reduce the computational cost to linear in the number of…

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An Exact Gibbs Sampler for the Markov-Modulated Poisson Process

马尔可夫调制泊松过程的精确Gibbs采样器

Summary A Markov-modulated Poisson process is a Poisson process whose intensity varies according to a Markov process. We present a novel technique for simulating from the exact distribution of a continuous time Markov chain over an interval given the start and end states and the infinitesimal generator, and we use this to create a Gibbs sampler which samples from the exact distribution of the hidden Markov chain in a Markov-modulated Poisson process. We apply the Gibbs…

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Exact and Computationally Efficient Likelihood-Based Estimation for Discretely Observed Diffusion Processes (with Discussion)

离散观测扩散过程的精确且计算高效的似然估计(含讨论)

Summary The objective of the paper is to present a novel methodology for likelihood-based inference for discretely observed diffusions. We propose Monte Carlo methods, which build on recent advances on the exact simulation of diffusions, for performing maximum likelihood and Bayesian estimation.

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Exact Filtering for Partially Observed Continuous Time Models

部分观测连续时间模型的精确滤波

Summary The forward–backward algorithm is an exact filtering algorithm which can efficiently calculate likelihoods, and which can be used to simulate from posterior distributions. Using a simple result which relates gamma random variables with different rates, we show how the forward–backward algorithm can be used to calculate the distribution of a sum of gamma random variables, and to simulate from their joint distribution given their sum. One application is to calculating…

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On-Line Inference for Hidden Markov Models via Particle Filters

利用粒子滤波进行隐马尔可夫模型的在线推断

Summary We consider the on-line Bayesian analysis of data by using a hidden Markov model, where inference is tractable conditional on the history of the state of the hidden component. A new particle filter algorithm is introduced and shown to produce promising results when analysing data of this type. The algorithm is similar to the mixture Kalman filter but uses a different resampling algorithm. We prove that this resampling algorithm is computationally efficient and…

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Approximate Likelihood Methods for Estimating Local Recombination Rates

局部重组率估计的近似似然方法

Summary There is currently great interest in understanding the way in which recombination rates vary, over short scales, across the human genome. Aside from inherent interest, an understanding of this local variation is essential for the sensible design and analysis of many studies aimed at elucidating the genetic basis of common diseases or of human population histories. Standard pedigree-based approaches do not have the fine scale resolution that is needed to address this…

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