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对 Choi 与 Bulgren《分布混合的估计程序》的评论AI 解读

Summary Choi and Bulgren's (1968) estimator for the mixing measure of a mixture of known distributions is biased in small samples; a variant of their estimator has a much smaller bias, and a smaller mean squared error, for mixtures of normal distributions differing in mean. The maximum-likelihood estimator is shown to be more computable than Choi and Bulgren suggest. Estimation is much more difficult when the component distributions are unknown; for example, a mixture of two…

由标记有丝分裂比例曲线进行统计推断AI 解读

The fraction labelled mitoses curve is widely used to study the premitotic phase of the cell cycle in proliferating cell populations. The population is here assumed to be in a steady state of exponential growth. The theoretical curve is derived in an explicit computational form, allowing for correlations between phases. This gives the likelihood function explicitly, and classical maximum likelihood methods of fitting the theoretical curve to experimental data can work very…

基于标记有丝分裂比例曲线的统计推断AI 解读

The fraction labelled mitoses curve is widely used to study the premitotic phase of the cell cycle in proliferating cell populations. The population is here assumed to be in a steady state of exponential growth. The theoretical curve is derived in an explicit computational form, allowing for correlations between phases. This gives the likelihood function explicitly, and classical maximum likelihood methods of fitting the theoretical curve to experimental data can work very…