A Mixture Model With Dependent Observations for the Analysis of CSFE–Labeling Experiments
用于 CFSE 标记实验分析的相关观测混合模型
Recent advances in flow cytometry have resulted in the development of powerful bioassays to analyze the proliferation of cell populations. The carboxy-fluorescein diacetate succinimidyl ester (CFSE)-labeling experiment is one such assay that is widely used to study cell kinetics and as a standard tool for investigating lymphocyte proliferation. Several mathematical models have been proposed to describe cell proliferation during CFSE experiments. The statistical analysis of…