Combining Data from Polymerase Chain Reaction DNA Typing Experiments: Applications to Sperm Typing Data
合并 PCR DNA 分型实验数据:精子分型的应用
The polymerase chain reaction (PCR) is a procedure by which the DNA in a single cell can be made to replicate many times in a test tube. By amplifying the DNA from individual sperm cells and typing the results, estimates of male recombination fractions can be made, which are valuable for creating genetic maps and locating regions of unusually intense crossover activity on the human genome. Because PCR typing results are subject to random error, stochastic models must be…