Identifying Genetic Variants for Addiction via Propensity Score Adjusted Generalized Kendall’s Tau
利用倾向得分调整的广义 Kendall’s Tau 识别成瘾遗传变异
Identifying replicable genetic variants for addiction has been extremely challenging. Besides the common difficulties with genome-wide association studies (GWAS), environmental factors are known to be critical to addiction, and comorbidity is widely observed. Despite the importance of environmental factors and comorbidity for addiction study, few GWAS analyses adequately considered them due to the limitations of the existing statistical methods. Although parametric methods…