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Designs for estimating the treatment effect in networks with interference

存在干扰的网络中处理效应估计的实验设计

In this paper, we introduce new, easily implementable designs for drawing causal inference from randomized experiments on networks with interference. Inspired by the idea of matching in observational studies, we introduce the notion of considering a treatment assignment as a “quasi-coloring” on a graph. Our idea of a perfect quasi-coloring strives to match every treated unit on a given network with a distinct control unit that has identical number of treated and control…

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Model Comparison and Assessment for Single Particle Tracking in Biological Fluids

生物流体单粒子追踪的模型比较与评估

State-of-the-art techniques in passive particle-tracking microscopy provide high-resolution path trajectories of diverse foreign particles in biological fluids. For particles on the order of 1 μm diameter, these paths are generally inconsistent with simple Brownian motion. Yet, despite an abundance of data confirming these findings and their wide-ranging scientific implications, stochastic modeling of the complex particle motion has received comparatively little attention.…

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Accelerating Asymptotically Exact MCMC for Computationally Intensive Models via Local Approximations

用局部近似加速计算密集模型的渐近精确 MCMC

We construct a new framework for accelerating Markov chain Monte Carlo in posterior sampling problems where standard methods are limited by the computational cost of the likelihood, or of numerical models embedded therein. Our approach introduces local approximations of these models into the Metropolis–Hastings kernel, borrowing ideas from deterministic approximation theory, optimization, and experimental design. Previous efforts at integrating approximate models into…

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Dirichlet–Laplace Priors for Optimal Shrinkage

用于最优收缩的 Dirichlet–Laplace 先验

regularization, are routinely used in high-dimensional applications, and there is a rich literature on optimality properties under sparsity assumptions. In the Bayesian paradigm, sparsity is routinely induced through two-component mixture priors having a probability mass at zero, but such priors encounter daunting computational problems in high dimensions. This has motivated continuous shrinkage priors, which can be expressed as global-local scale mixtures of Gaussians,…

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Causal Inference from 2K Factorial Designs by Using Potential Outcomes

两水平析因设计的潜在结果因果推断

Summary A framework for causal inference from two-level factorial designs is proposed, which uses potential outcomes to define causal effects. The paper explores the effect of non-additivity of unit level treatment effects on Neyman's repeated sampling approach for estimation of causal effects and on Fisher's randomization tests on sharp null hypotheses in these designs. The framework allows for statistical inference from a finite population, permits definition and…

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Hypothesis testing for high-dimensional sparse binary regression

高维稀疏二元回归的假设检验

In this paper, we study the detection boundary for minimax hypothesis testing in the context of high-dimensional, sparse binary regression models. Motivated by genetic sequencing association studies for rare variant effects, we investigate the complexity of the hypothesis testing problem when the design matrix is sparse. We observe a new phenomenon in the behavior of detection boundary which does not occur in the case of Gaussian linear regression. We derive the detection…

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Relevant Statistics for Bayesian Model Choice

贝叶斯模型选择中的相关摘要统计量

Summary The choice of the summary statistics that are used in Bayesian inference and in particular in approximate Bayesian computation algorithms has bearings on the validation of the resulting inference. Those statistics are nonetheless customarily used in approximate Bayesian computation algorithms without consistency checks. We derive necessary and sufficient conditions on summary statistics for the corresponding Bayes factor to be convergent, namely to select the true…

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Posterior contraction in sparse Bayesian factor models for massive covariance matrices

超大协方差矩阵稀疏贝叶斯因子模型的后验收缩

Sparse Bayesian factor models are routinely implemented for parsimonious dependence modeling and dimensionality reduction in high-dimensional applications. We provide theoretical understanding of such Bayesian procedures in terms of posterior convergence rates in inferring high-dimensional covariance matrices where the dimension can be larger than the sample size. Under relevant sparsity assumptions on the true covariance matrix, we show that commonly-used point mass mixture…

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Edge universality of correlation matrices

相关矩阵的谱边缘普适性

Let $\widetilde{X}_{M\times N}$ be a rectangular data matrix with independent real-valued entries $[\widetilde{x}_{ij}]$ satisfying $\mathbb{E} \widetilde{x}_{ij}=0$ and $\mathbb{E} \widetilde{x}^{2}_{ij}=\frac{1}{M}$, $N,M\to\infty$. These entries have a subexponential decay at the tails. We will be working in the regime $N/M=d_{N}$, $\lim_{N\to\infty}d_{N}\neq0,1,\infty$. In this paper we prove the edge universality of correlation matrices ${X}^{\dagger}X$, where the…

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