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重印：高维线性中介模型推断及新冠疫情股票反应应用AI 解读

Mediation analysis draws increasing attention in many research areas such as economics, finance and social sciences. In this paper, we propose new statistical inference procedures for high dimensional mediation models, in which both the outcome model and the mediator model are linear with high dimensional mediators. Traditional procedures for mediation analysis cannot be used to make statistical inference for high dimensional linear mediation models due to…

高维潜在中介变量下广义中介模型的估计与检验AI 解读

Motivated by an empirical analysis of stock reaction to COVID-19 pandemic, we propose a generalized mediation model with high-dimensional potential mediators to study the mediation effects of financial metrics that bridge company’s sector and stock value. We propose an estimation procedure for the direct effect via a partial penalized maximum likelihood method and establish its theoretical properties. We develop a Wald test for the indirect effect and show that the proposed…

高维线性中介模型的统计推断及疫情股票反应应用AI 解读

Mediation analysis draws increasing attention in many research areas such as economics, finance and social sciences. In this paper, we propose new statistical inference procedures for high dimensional mediation models, in which both the outcome model and the mediator model are linear with high dimensional mediators. Traditional procedures for mediation analysis cannot be used to make statistical inference for high dimensional linear mediation models due to…

高维中介分析：筛选连接童年创伤与皮质醇应激反应的 DNA 甲基化位点AI 解读

Childhood trauma tends to influence cortisol stress reactivity through the mediating effects of DNA methylation. Houtepen et al. conducted a study to investigate the role of DNA methylation in cortisol stress reactivity and its relationship with childhood trauma. The study collected a dataset consisting of 385,882 DNA methylation loci, cortisol stress reactivity, one-dimensional score on a childhood trauma questionnaire and several covariates for 85 healthy individuals. Of…