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Minimum Volume Conformal Sets for Multivariate Regression

多元回归的最小体积保形预测集

Conformal prediction provides a principled framework for constructing predictive sets with finite-sample validity. While much of the focus has been on univariate response variables, existing multivariate methods either impose rigid geometric assumptions or rely on flexible but computationally expensive approaches that do not explicitly optimize prediction set volume. We propose an optimization-driven framework based on a novel loss function that directly learns…

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Valid Inference After Causal Discovery

因果发现之后的有效推断

Causal discovery and causal effect estimation are two fundamental tasks in causal inference. While many methods have been developed for each task individually, statistical challenges arise when applying these methods jointly: estimating causal effects after running causal discovery algorithms on the same data leads to "double dipping," invalidating the coverage guarantees of classical confidence intervals. To this end, we develop tools for valid post-causal-discovery…

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Reinforcement Learning in Latent Heterogeneous Environments

潜在异质环境中的强化学习

Reinforcement Learning holds great promise for data-driven decision-making in various social contexts, including healthcare, education, and business. However, classical methods that focus on the mean of the total return may yield misleading results when dealing with heterogeneous populations typically found in large-scale datasets. To address this issue, we introduce the K-Value Heterogeneous Markov Decision Process, a framework designed to handle sequential decision…

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Bayesian Robustness: A Nonasymptotic Viewpoint

贝叶斯稳健性:非渐近视角

We study the problem of robustly estimating the posterior distribution for the setting where observed data can be contaminated with potentially adversarial outliers. We propose Rob-ULA, a robust variant of the Unadjusted Langevin Algorithm (ULA), and provide a finite-sample analysis of its sampling distribution. In particular, we show that after T=O˜(d/εacc) iterations, we can sample from pT such that dist(pT,p*)≤εacc+O˜(ϵ), where ϵ is the fraction of corruptions and dist…

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Post-selection inference via algorithmic stability

通过算法稳定性进行选择后推断

When the target of statistical inference is chosen in a data-driven manner, the guarantees provided by classical theories vanish. We propose a solution to the problem of inference after selection by building on the framework of algorithmic stability, in particular its branch with origins in the field of differential privacy. Stability is achieved via randomization of selection and it serves as a quantitative measure that is sufficient to obtain nontrivial post-selection…

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Singularity, misspecification and the convergence rate of EM

奇异性、模型误设与EM算法的收敛速度

A line of recent work has analyzed the behavior of the Expectation-Maximization (EM) algorithm in the well-specified setting, in which the population likelihood is locally strongly concave around its maximizing argument. Examples include suitably separated Gaussian mixture models and mixtures of linear regressions. We consider over-specified settings in which the number of fitted components is larger than the number of components in the true distribution. Such mis-specified…

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A unified treatment of multiple testing with prior knowledge using the p-filter

利用 p-filter 统一处理含先验知识的多重检验

There is a significant literature on methods for incorporating knowledge into multiple testing procedures so as to improve their power and precision. Some common forms of prior knowledge include (a) beliefs about which hypotheses are null, modeled by nonuniform prior weights; (b) differing importances of hypotheses, modeled by differing penalties for false discoveries; (c) multiple arbitrary partitions of the hypotheses into (possibly overlapping) groups and (d) knowledge of…

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Communication-Efficient Distributed Statistical Inference

通信高效的分布式统计推断

We present a communication-efficient surrogate likelihood (CSL) framework for solving distributed statistical inference problems. CSL provides a communication-efficient surrogate to the global likelihood that can be used for low-dimensional estimation, high-dimensional regularized estimation, and Bayesian inference. For low-dimensional estimation, CSL provably improves upon naive averaging schemes and facilitates the construction of confidence intervals. For high-dimensional…

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Minimax Optimal Procedures for Locally Private Estimation

局部隐私估计的极小极大最优程序

Working under a model of privacy in which data remain private even from the statistician, we study the tradeoff between privacy guarantees and the risk of the resulting statistical estimators. We develop private versions of classical information-theoretical bounds, in particular those due to Le Cam, Fano, and Assouad. These inequalities allow for a precise characterization of statistical rates under local privacy constraints and the development of provably (minimax) optimal…

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Mining Massive Amounts of Genomic Data: A Semiparametric Topic Modeling Approach

海量基因组数据挖掘:半参数主题建模方法

Characterizing the functional relevance of transcription factors (TFs) in different biological contexts is pivotal in systems biology. Given the massive amount of genomic data, computational identification of TFs is emerging as a useful approach to bridge functional genomics with disease risk loci. In this article, we use large-scale gene expression and chromatin immunoprecipitation (ChIP) data corpuses to conduct high-throughput TF-biological context association analysis.…

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On the computational complexity of high-dimensional Bayesian variable selection

高维贝叶斯变量选择的计算复杂度

We study the computational complexity of Markov chain Monte Carlo (MCMC) methods for high-dimensional Bayesian linear regression under sparsity constraints. We first show that a Bayesian approach can achieve variable-selection consistency under relatively mild conditions on the design matrix. We then demonstrate that the statistical criterion of posterior concentration need not imply the computational desideratum of rapid mixing of the MCMC algorithm. By introducing a…

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A Scalable Bootstrap for Massive Data

面向海量数据的可扩展自助法

Summary The bootstrap provides a simple and powerful means of assessing the quality of estimators. However, in settings involving large data sets—which are increasingly prevalent—the calculation of bootstrap-based quantities can be prohibitively demanding computationally. Although variants such as subsampling and the m out of n bootstrap can be used in principle to reduce the cost of bootstrap computations, these methods are generally not robust to specification of tuning…

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The asymptotics of ranking algorithms

排序算法的渐近理论

We consider the predictive problem of supervised ranking, where the task is to rank sets of candidate items returned in response to queries. Although there exist statistical procedures that come with guarantees of consistency in this setting, these procedures require that individuals provide a complete ranking of all items, which is rarely feasible in practice. Instead, individuals routinely provide partial preference information, such as pairwise comparisons of items, and…

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Support union recovery in high-dimensional multivariate regression

高维多元回归中的支持集并集恢复

In multivariate regression, a K-dimensional response vector is regressed upon a common set of p covariates, with a matrix B∗ ∈ ℝp × K of regression coefficients. We study the behavior of the multivariate group Lasso, in which block regularization based on the ℓ1 ∕ ℓ2 norm is used for support union recovery, or recovery of the set of s rows for which B∗ is nonzero. Under high-dimensional scaling, we show that the multivariate group Lasso exhibits a threshold for the recovery…

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Kernel dimension reduction in regression

回归中的核降维

We present a new methodology for sufficient dimension reduction (SDR). Our methodology derives directly from the formulation of SDR in terms of the conditional independence of the covariate X from the response Y, given the projection of X on the central subspace [cf. J. Amer. Statist. Assoc. 86 (1991) 316–342 and Regression Graphics (1998) Wiley]. We show that this conditional independence assertion can be characterized in terms of conditional covariance operators on…

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On surrogate loss functions and f-divergences

替代损失函数与 f 散度

The goal of binary classification is to estimate a discriminant function γ from observations of covariate vectors and corresponding binary labels. We consider an elaboration of this problem in which the covariates are not available directly but are transformed by a dimensionality-reducing quantizer Q. We present conditions on loss functions such that empirical risk minimization yields Bayes consistency when both the discriminant function and the quantizer are estimated.…

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