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Bayesian Random-Effects Meta-Analysis Integrating Individual Participant Data and Aggregate Data

整合个体数据与汇总数据的贝叶斯随机效应元分析

Meta-analysis using individual participant data (IPD) offers many benefits, including greater analytical flexibility, compared to conventional analyses based on aggregate data (AD). However, it is often hindered by restricted access to IPD. Relying solely on available IPD may introduce “data availability bias,” compromising external validity. Integrating IPD with relevant AD addresses this concern, but existing methods are restrictive, requiring precise knowledge of the…

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Semiparametric Approach to a Random Effects Quantile Regression Model

随机效应分位数回归模型的半参数方法

We consider a random effects quantile regression analysis of clustered data and propose a semiparametric approach using empirical likelihood. The random regression coefficients are assumed independent with a common mean, following parametrically specified distributions. The common mean corresponds to the population-average effects of explanatory variables on the conditional quantile of interest, while the random coefficients represent cluster specific deviations in the…

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Quantile regression with varying coefficients

变系数分位数回归

Quantile regression provides a framework for modeling statistical quantities of interest other than the conditional mean. The regression methodology is well developed for linear models, but less so for nonparametric models. We consider conditional quantiles with varying coefficients and propose a methodology for their estimation and assessment using polynomial splines. The proposed estimators are easy to compute via standard quantile regression algorithms and a stepwise knot…

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