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Bayesian predictive decision synthesis

贝叶斯预测决策综合

Abstract Decision-guided perspectives on model uncertainty expand traditional statistical thinking about managing, comparing, and combining inferences from sets of models. Bayesian predictive decision synthesis (BPDS) advances conceptual and theoretical foundations, and defines new methodology that explicitly integrates decision-analytic outcomes into the evaluation, comparison, and potential combination of candidate models. BPDS extends recent theoretical and practical…

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Bayesian Forecasting of Many Count-Valued Time Series

多条计数时间序列的贝叶斯预测

We develop and exemplify application of new classes of dynamic models for time series of nonnegative counts. Our novel univariate models combine dynamic generalized linear models for binary and conditionally Poisson time series, with dynamic random effects for over-dispersion. These models estimate dynamic regression coefficients in both binary and nonzero count components. Sequential Bayesian analysis allows fast, parallel analysis of sets of decoupled time series. New…

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Multivariate Bayesian Predictive Synthesis in Macroeconomic Forecasting

宏观经济预测中的多变量贝叶斯预测综合

We present new methodology and a case study in use of a class of Bayesian predictive synthesis (BPS) models for multivariate time series forecasting. This extends the foundational BPS framework to the multivariate setting, with detailed application in the topical and challenging context of multistep macroeconomic forecasting in a monetary policy setting. BPS evaluates—sequentially and adaptively over time—varying forecast biases and facets of miscalibration of individual…

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Dynamic Bayesian predictive synthesis in time series forecasting

时间序列预测中的动态贝叶斯预测综合

We discuss model and forecast combination in time series forecasting. A foundational Bayesian perspective based on agent opinion analysis theory defines a new framework for density forecast combination, and encompasses several existing forecast pooling methods. We develop a novel class of dynamic latent factor models for time series forecast synthesis; simulation-based computation enables implementation. These models can dynamically adapt to time-varying biases,…

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Scalable Bayesian Modeling, Monitoring, and Analysis of Dynamic Network Flow Data

动态网络流量数据的可扩展贝叶斯建模、监测与分析

Traffic flow count data in networks arise in many applications, such as automobile or aviation transportation, certain directed social network contexts, and Internet studies. Using an example of Internet browser traffic flow through site-segments of an international news website, we present Bayesian analyses of two linked classes of models which, in tandem, allow fast, scalable, and interpretable Bayesian inference. We first develop flexible state-space models for streaming…

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Bayesian Analysis of Latent Threshold Dynamic Models

潜在阈值动态模型的贝叶斯分析

We discuss a general approach to dynamic sparsity modeling in multivariate time series analysis. Time-varying parameters are linked to latent processes that are thresholded to induce zero values adaptively, providing natural mechanisms for dynamic variable inclusion/selection. We discuss Bayesian model specification, analysis and prediction in dynamic regressions, time-varying vector autoregressions, and multivariate volatility models using latent thresholding. Application…

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Bayesian Spatio-Dynamic Modeling in Cell Motility Studies: Learning Nonlinear Taxic Fields Guiding the Immune Response

细胞运动的贝叶斯时空动态建模:学习引导免疫反应的非线性趋性场

Ioanna Manolopouloua, Melanie P. Matheub, Michael D. Cahalanb, Mike Westa & Thomas B. Keplerc a Department of Statistical Science , Duke University , Durham , NC , 27708 b Department of Physiology and Biophysics, School of Medicine , University of California , Irvine , CA , 92697 c Department of Microbiology , Boston University School of Medicine , Boston , MA , 02118 We develop and analyze models of the spatio-temporal organization of lymphocytes in the lymph nodes and…

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High-Dimensional Sparse Factor Modeling: Applications in Gene Expression Genomics

高维稀疏因子建模:基因表达组学应用

We describe studies in molecular profiling and biological pathway analysis that use sparse latent factor and regression models for microarray gene expression data. We discuss breast cancer applications and key aspects of the modeling and computational methodology. Our case studies aim to investigate and characterize heterogeneity of structure related to specific oncogenic pathways, as well as links between aggregate patterns in gene expression profiles and clinical…

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Covariance decomposition in undirected Gaussian graphical models

无向高斯图模型中的协方差分解

The covariance between two variables in a multivariate Gaussian distribution is decomposed into a sum of path weights for all paths connecting the two variables in an undirected independence graph. These weights are useful in determining which variables are important in mediating correlation between the two path endpoints. The decomposition arises in undirected Gaussian graphical models and does not require or involve any assumptions of causality. This covariance…

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Monte Carlo Smoothing for Nonlinear Time Series

非线性时间序列的蒙特卡洛平滑

We develop methods for performing smoothing computations in general state-space models. The methods rely on a particle representation of the filtering distributions, and their evolution through time using sequential importance sampling and resampling ideas. In particular, novel techniques are presented for generation of sample realizations of historical state sequences. This is carried out in a forward-filtering backward-smoothing procedure that can be viewed as the…

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Priors and Component Structures in Autoregressive Time Series Models

自回归时间序列模型中的先验与成分结构

Gabriel Huerta, Mike West; Priors and Component Structures in Autoregressive Time Series Models, Journal of the Royal Statistical Society Series B: Statistical

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Bayesian Dynamic Factor Models and Portfolio Allocation

贝叶斯动态因子模型与投资组合配置

We discuss the development of dynamic factor models for multivariate financial time series, and the incorporation of stochastic volatility components for latent factor processes. Bayesian inference and computation is developed and explored in a study of the dynamic factor structure of daily spot exchange rates for a selection of international currencies. The models are direct generalizations of univariate stochastic volatility models and represent specific varieties of…

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Evaluation and Comparison of EEG Traces: Latent Structure in Nonstationary Time Series

脑电轨迹的评价与比较:非平稳时间序列的潜在结构

We explore and illustrate the use of time series decomposition methods for evaluating and comparing latent structure in nonstationary electroencephalographic (EEG) traces obtained from depressed patients during brain seizures induced as part of electroconvulsive therapy (ECT). Analysis of the patterns of change over time in the frequency structure of such EEG data provides insight into the neurophysiological mechanisms of action of this effective but poorly understood…

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Evaluation and Comparison of EEG Traces: Latent Structure in Nonstationary Time Series

脑电轨迹的评估与比较:非平稳时间序列中的潜在结构

We explore and illustrate the use of time series decomposition methods for evaluating and comparing latent structure in nonstationary electroencephalographic (EEG) traces obtained from depressed patients during brain seizures induced as part of electroconvulsive therapy (ECT). Analysis of the patterns of change over time in the frequency structure of such EEG data provides insight into the neurophysiological mechanisms of action of this effective but poorly understood…

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Priors and Component Structures in Autoregressive Time Series Models

自回归时间序列模型的先验与成分结构

Summary New approaches to prior specification and structuring in autoregressive time series models are introduced and developed. We focus on defining classes of prior distributions for parameters and latent variables related to latent components of an autoregressive model for an observed time series. These new priors naturally permit the incorporation of both qualitative and quantitative prior information about the number and relative importance of physically meaningful…

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Evaluation and Comparison of EEG Traces: Latent Structure in Nonstationary Time Series

脑电轨迹的评估与比较:非平稳时间序列中的潜在结构

We explore and illustrate the use of time series decomposition methods for evaluating and comparing latent structure in nonstationary electroencephalographic (EEG) traces obtained from depressed patients during brain seizures induced as part of electroconvulsive therapy (ECT). Analysis of the patterns of change over time in the frequency structure of such EEG data provides insight into the neurophysiological mechanisms of action of this effective but poorly understood…

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Evaluation and Comparison of EEG Traces: Latent Structure in Nonstationary Time Series

脑电轨迹的评估与比较:非平稳时间序列中的潜在结构

We explore and illustrate the use of time series decomposition methods for evaluating and comparing latent structure in nonstationary electroencephalographic (EEG) traces obtained from depressed patients during brain seizures induced as part of electroconvulsive therapy (ECT). Analysis of the patterns of change over time in the frequency structure of such EEG data provides insight into the neurophysiological mechanisms of action of this effective but poorly understood…

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Bayesian Inference on Network Traffic Using Link Count Data

利用链路计数数据进行网络流量的贝叶斯推断

We study Bayesian models and methods for analysing network traffic counts in problems of inference about the traffic intensity between directed pairs of origins and destinations in networks. This is a class of problems very recently discussed by Vardi in a 1996 JASA article and is of interest in both communication and transportation network studies. The current article develops the theoretical framework of variants of the origin-destination flow problem and introduces…

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Bayesian Forecasting of Multinomial Time Series through Conditionally Gaussian Dynamic Models

通过条件高斯动态模型进行多项时间序列的贝叶斯预测

We consider inference in the class of conditionally Gaussian dynamic models for nonnormal multivariate time series. In such models, data are represented as drawn from nonnormal sampling distributions whose parameters are related both through time and hierarchically across several multivariate series. A key example—the main focus here—is time series of multinomial observations, a common occurrence in sociological and demographic studies involving categorical count data.…

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Hierarchical Mixture Models in Neurological Transmission Analysis

神经传递分析中的层级混合模型

Hierarchically structured mixture models are studied in the context of data analysis and inference on neural synaptic transmission characteristics in mammalian, and other, central nervous systems. Mixture structures arise due to uncertainties about the stochastic mechanisms governing the responses to electrochemical stimulation of individual neurotransmitter release sites at nerve junctions. Models attempt to capture such scientific features as the sensitivity of individual…

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Hierarchical Mixture Models in Neurological Transmission Analysis

神经传递分析中的层级混合模型

Hierarchically structured mixture models are studied in the context of data analysis and inference on neural synaptic transmission characteristics in mammalian, and other, central nervous systems. Mixture structures arise due to uncertainties about the stochastic mechanisms governing the responses to electrochemical stimulation of individual neurotransmitter release sites at nerve junctions. Models attempt to capture such scientific features as the sensitivity of individual…

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Bayesian Inference in Cyclical Component Dynamic Linear Models

周期成分动态线性模型的贝叶斯推断

Dynamic linear models (DLM's) with time-varying cyclical components are developed for the analysis of time series with persistent though time-varying cyclical behavior. The development covers inference on wavelengths of possibly several persistent cycles in nonstationary time series, permitting explicit time variation in amplitudes and phases of component waveforms, decomposition of stochastic inputs into purely observational noise and innovations that impact on the waveform…

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