Aggregate Data Studies of Disease Risk Factors
疾病风险因素的聚合数据研究
Statistical methods are proposed for estimating relative rate parameters, based on estimated disease rates and covariate data from random samples of individuals from each of several cohorts. A random effects model is used to derive mean and variance models for estimated disease rates. Estimating equations for relative rate parameters are then developed by replacing cohort covariate averages by corresponding sample averages. The asymptotic distribution of regression parameter…