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Bayesian Gaussian Copula Factor Models for Mixed Data

混合数据的贝叶斯高斯 Copula 因子模型

Gaussian factor models have proven widely useful for parsimoniously characterizing dependence in multivariate data. There is a rich literature on their extension to mixed categorical and continuous variables, using latent Gaussian variables or through generalized latent trait models acommodating measurements in the exponential family. However, when generalizing to non-Gaussian measured variables the latent variables typically influence both the dependence structure and the…

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Predicting Viral Infection From High-Dimensional Biomarker Trajectories

利用高维生物标志物轨迹预测病毒感染

There is often interest in predicting an individual's latent health status based on high-dimensional biomarkers that vary over time. Motivated by time-course gene expression array data that we have collected in two influenza challenge studies performed with healthy human volunteers, we develop a novel time-aligned Bayesian dynamic factor analysis methodology. The time course trajectories in the gene expressions are related to a relatively low-dimensional vector of latent…

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Dynamic Nonparametric Bayesian Models for Analysis of Music

用于音乐分析的动态非参数贝叶斯模型

The dynamic hierarchical Dirichlet process (dHDP) is developed to model complex sequential data, with a focus on audio signals from music. The music is represented in terms of a sequence of discrete observations, and the sequence is modeled using a hidden Markov model (HMM) with time-evolving parameters. The dHDP imposes the belief that observations that are temporally proximate are more likely to be drawn from HMMs with similar parameters, while also allowing for…

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The Matrix Stick-Breaking Process

矩阵折棒过程

In analyzing data from multiple related studies, it often is of interest to borrow information across studies and to cluster similar studies. Although parametric hierarchical models are commonly used, of concern is sensitivity to the form chosen for the random-effects distribution. A Dirichlet process (DP) prior can allow the distribution to be unknown, while clustering studies; however, the DP does not allow local clustering of studies with respect to a subset of the…

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