Universal optimality of Patterson’s crossover designs
Patterson 交叉试验设计的普遍最优性
We show that the balanced crossover designs given by Patterson [Biometrika 39 (1952) 32–48] are (a) universally optimal (UO) for the joint estimation of direct and residual effects when the competing class is the class of connected binary designs and (b) UO for the estimation of direct (residual) effects when the competing class of designs is the class of connected designs (which includes the connected binary designs) in which no treatment is given to the same subject in…