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This paper considers the analysis of current status data with a cured proportion in the population using a mixture model that combines a logistic regression formulation for the probability of cure with a semiparametric regression model for the time to occurrence of the event. The semiparametric regression model belongs to the flexible class of partly linear models that allows one to explore the possibly nonlinear effect of a certain covariate on the response variable. A…

脆弱性模型估计的边际似然方法AI 解读

A marginal likelihood approach is proposed for estimating the parameters in a frailty model using clustered survival data. To overcome the analytic intractability of the marginal likelihood function, we propose a Monte Carlo approximation using the technique of importance sampling. Implementation is by means of simulations from the uniform distribution. The suggested method can cope with censoring and unequal cluster sizes and can be applied to any frailty distribution with…