Nonparametric Two-Sample Comparisons of Changes on Ordinal Responses
有序响应变化的非参数两样本比较
We discuss two-armed clinical trials in which an ordinal response is observed on entry and at follow-up. In certain subject areas, such data are often reduced to the counts of patients who have deteriorated, remained the same, or improved. We develop asymptotic distribution theory to compare this approach to the use of nonparametric tests based on poststratification of the follow-up responses according to the entry levels. The theory for the latter approach is established by…