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通过剖面化迁移学习消除混杂AI 解读

Unmeasured confounders are a major source of bias in regression-based effect estimation and causal inference. In this paper, we propose a new profiled transfer learning framework, ProTrans, to address confounding effects in the target dataset, when additional source datasets with similar confounding structures are available. We introduce the concept of profiled residuals to characterize the shared confounding patterns between source and target datasets. By incorporating…

高维暴露与高维中介模型的统计推断AI 解读

High-dimensional mediation analysis has gained increasing interest in various fields, particularly in genetic and medical research. Compared with existing works that focus mainly on high-dimensional mediators, this paper advocates a new framework of Partial Regularization-based Inference for Mediation Effects (PRIME) when both exposures and mediators are high-dimensional. Estimated direct and indirect effects are established using a group-wise partially penalized least…

重印：高维线性中介模型推断及新冠疫情股票反应应用AI 解读

Mediation analysis draws increasing attention in many research areas such as economics, finance and social sciences. In this paper, we propose new statistical inference procedures for high dimensional mediation models, in which both the outcome model and the mediator model are linear with high dimensional mediators. Traditional procedures for mediation analysis cannot be used to make statistical inference for high dimensional linear mediation models due to…

结构变化检测中控制错误发现率的广义Knockoff程序AI 解读

Controlling false discovery rate (FDR) is crucial for variable selection, multiple testing, among other signal detection problems. In literature, there is certainly no shortage of FDR control strategies when selecting individual features, but the relevant works for structural change detection, such as profile analysis for piecewise constant coefficients and integration analysis with multiple data sources, are limited. In this paper, we propose a generalized knockoff…

高维潜在中介变量下广义中介模型的估计与检验AI 解读

Motivated by an empirical analysis of stock reaction to COVID-19 pandemic, we propose a generalized mediation model with high-dimensional potential mediators to study the mediation effects of financial metrics that bridge company’s sector and stock value. We propose an estimation procedure for the direct effect via a partial penalized maximum likelihood method and establish its theoretical properties. We develop a Wald test for the indirect effect and show that the proposed…

高维线性中介模型的统计推断及疫情股票反应应用AI 解读

Mediation analysis draws increasing attention in many research areas such as economics, finance and social sciences. In this paper, we propose new statistical inference procedures for high dimensional mediation models, in which both the outcome model and the mediator model are linear with high dimensional mediators. Traditional procedures for mediation analysis cannot be used to make statistical inference for high dimensional linear mediation models due to…

变系数中介模型及其在行为经济学数据分析中的应用AI 解读

This paper is concerned with causal mediation analysis with varying indirect and direct effects. We propose a varying coefficient mediation model, which can also be viewed as an extension of moderation analysis on a causal diagram. We develop a new estimation procedure for the direct and indirect effects based on B-splines. Under mild conditions, rates of convergence and asymptotic distributions of the resulting estimates are established. We further propose a F-type test for…

高维中介分析：筛选连接童年创伤与皮质醇应激反应的 DNA 甲基化位点AI 解读

Childhood trauma tends to influence cortisol stress reactivity through the mediating effects of DNA methylation. Houtepen et al. conducted a study to investigate the role of DNA methylation in cortisol stress reactivity and its relationship with childhood trauma. The study collected a dataset consisting of 385,882 DNA methylation loci, cortisol stress reactivity, one-dimensional score on a childhood trauma questionnaire and several covariates for 85 healthy individuals. Of…

利用 Knockoff 特征进行无模型特征筛选与错误发现率控制AI 解读

This article proposes a model-free and data-adaptive feature screening method for ultrahigh-dimensional data. The proposed method is based on the projection correlation which measures the dependence between two random vectors. This projection correlation based method does not require specifying a regression model, and applies to data in the presence of heavy tails and multivariate responses. It enjoys both sure screening and rank consistency properties under weak…

向量空间模型中的序贯文本词项选择AI 解读

Text mining has recently attracted a great deal of attention with the accumulation of text documents in all fields. In this article, we focus on the use of textual information to explain continuous variables in the framework of linear regressions. To handle the unstructured texts, one common practice is to structuralize the text documents via vector space models. However, using words or phrases as the basic analysis terms in vector space models is in high debate. In…

超高维协变量变系数模型的特征选择AI 解读

This paper is concerned with feature screening and variable selection for varying coefficient models with ultrahigh dimensional covariates. We propose a new feature screening procedure for these models based on conditional correlation coefficient. We systematically study the theoretical properties of the proposed procedure, and establish their sure screening property and the ranking consistency. To enhance the finite sample performance of the proposed procedure, we further…