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Analysis of variance, coefficient of determination and F-test for local polynomial regression

局部多项式回归的方差分析、决定系数与 F 检验

This paper provides ANOVA inference for nonparametric local polynomial regression (LPR) in analogy with ANOVA tools for the classical linear regression model. A surprisingly simple and exact local ANOVA decomposition is established, and a local R-squared quantity is defined to measure the proportion of local variation explained by fitting LPR. A global ANOVA decomposition is obtained by integrating local counterparts, and a global R-squared and a symmetric projection matrix…

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Efficient Local Estimation for Time-Varying Coefficients in Deterministic Dynamic Models With Applications to HIV-1 Dynamics

确定性动态模型中时变系数的高效局部估计及 HIV-1 应用

Recently deterministic dynamic models have become very popular in biomedical research and other scientific areas; examples include modeling human immunodeficiency virus (HIV) dynamics, pharmacokinetic/pharmacodynamic analysis, tumor cell kinetics, and genetic network modeling. In this article we propose estimation methods for the time-varying coefficients in deterministic dynamic systems that are usually described by a set of differential equations. Three two-stage local…

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Statistical inferences for functional data

函数型数据的统计推断

With modern technology development, functional data are being observed frequently in many scientific fields. A popular method for analyzing such functional data is “smoothing first, then estimation.” That is, statistical inference such as estimation and hypothesis testing about functional data is conducted based on the substitution of the underlying individual functions by their reconstructions obtained by one smoothing technique or another. However, little is known about…

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