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动态协变量平衡：利用潜在结果局部投影估计跨期处理效应AI 解读

Abstract This article concerns the estimation and inference of treatment effects in panel data settings when treatments change dynamically over time. We propose a balancing method that allows for (i) treatments to be assigned dynamically over time based on high-dimensional covariates, past outcomes and treatments; (ii) outcomes and time-varying covariates to depend on the trajectory of all past treatments; and (iii) heterogeneity of treatment effects. Our approach…

可能误设的边际结构 Cox 模型下的双重稳健估计AI 解读

Summary In this article we consider the marginal structural Cox model, which has been widely used to analyse observational studies with survival outcomes. The standard inverse probability weighting method under the model hinges on a propensity score model for the treatment assignment and a censoring model that incorporates both the treatment and the covariates. In such settings model misspecification can often occur, and the Cox regression model’s non-collapsibility has…

动态处理效应的高维推断AI 解读

Estimating dynamic treatment effects is a crucial endeavor in causal inference, particularly when confronted with high-dimensional confounders. Doubly robust (DR) approaches have emerged as promising tools for estimating treatment effects due to their flexibility. However, we showcase that the traditional DR approaches that only focus on the DR representation of the expected outcomes may fall short of delivering optimal results. In this paper, we propose a novel DR…

公平的政策定向配置AI 解读

One of the major concerns of targeting interventions on individuals in social welfare programs is discrimination: individualized treatments may induce disparities across sensitive attributes such as age, gender, or race. This article addresses the question of the design of fair and efficient treatment allocation rules. We adopt the nonmaleficence perspective of “first do no harm”: we select the fairest allocation within the Pareto frontier. We cast the optimization into a…

Synthetic Learner：随时间变化的处理效应无模型推断AI 解读

Understanding the effect of a particular treatment or a policy pertains to many areas of interest, ranging from political economics, marketing to healthcare. In this paper, we develop a non-parametric algorithm for detecting the effects of treatment over time in the context of Synthetic Controls. The method builds on counterfactual predictions from many algorithms without necessarily assuming that the algorithms correctly capture the model. We introduce an inferential…

高维混杂下加性风险模型的治疗效应估计AI 解读

Estimating treatment effects for survival outcomes in the high-dimensional setting is critical for many biomedical applications and any application with censored observations. This article establishes an “orthogonal” score for learning treatment effects, using observational data with a potentially large number of confounders. The estimator allows for root-n, asymptotically valid confidence intervals, despite the bias induced by the regularization. Moreover, we develop a…

高维半监督学习：寻求均值的最优推断AI 解读

Summary A fundamental challenge in semi-supervised learning lies in the observed data’s disproportional size when compared with the size of the data collected with missing outcomes. An implicit understanding is that the dataset with missing outcomes, being significantly larger, ought to improve estimation and inference. However, it is unclear to what extent this is correct. We illustrate one clear benefit: root-$n$ inference of the outcome’s mean is possible while only…

非稀疏高维线性模型的可检验性AI 解读

Understanding statistical inference under possibly nonsparse high-dimensional models has gained much interest recently. For a given component of the regression coefficient, we show that the difficulty of the problem depends on the sparsity of the corresponding row of the precision matrix of the covariates, not the sparsity of the regression coefficients. We develop new concepts of uniform and essentially uniform nontestability that allow the study of limitations of tests…

高维回归中免手工调参的稳健高效方法AI 解读

We introduce a novel approach for high-dimensional regression with theoretical guarantees. The new procedure overcomes the challenge of tuning parameter selection of Lasso and possesses several appealing properties. It uses an easily simulated tuning parameter that automatically adapts to both the unknown random error distribution and the correlation structure of the design matrix. It is robust with substantial efficiency gain for heavy-tailed random errors while maintaining…

高维线性混合模型中的固定效应检验AI 解读

Many scientific and engineering challenges—ranging from pharmacokinetic drug dosage allocation and personalized medicine to marketing mix (4Ps) recommendations—require an understanding of the unobserved heterogeneity to develop the best decision making-processes. In this article, we develop a hypothesis test and the corresponding p-value for testing for the significance of the homogeneous structure in linear mixed models. A robust matching moment construction is used for…

稠密高维线性模型中的线性假设检验AI 解读

We propose a methodology for testing linear hypothesis in high-dimensional linear models. The proposed test does not impose any restriction on the size of the model, that is, model sparsity or the loading vector representing the hypothesis. Providing asymptotically valid methods for testing general linear functions of the regression parameters in high-dimensions is extremely challenging—especially without making restrictive or unverifiable assumptions on the number of…

存在异常值时的提升学习：基于非凸损失的自适应分类AI 解读

This article examines the role and the efficiency of nonconvex loss functions for binary classification problems. In particular, we investigate how to design adaptive and effective boosting algorithms that are robust to the presence of outliers in the data or to the presence of errors in the observed data labels. We demonstrate that nonconvex losses play an important role for prediction accuracy because of the diminishing gradient properties—the ability of the losses to…

非多项式维度下 Cox 比例风险模型的正则化AI 解读

High throughput genetic sequencing arrays with thousands of measurements per sample and a great amount of related censored clinical data have increased demanding need for better measurement specific model selection. In this paper we establish strong oracle properties of non-concave penalized methods for non-polynomial (NP) dimensional data with censoring in the framework of Cox's proportional hazards model. A class of folded-concave penalties are employed and both LASSO and…

用于超高维变量选择的惩罚复合准似然AI 解读

Summary In high dimensional model selection problems, penalized least square approaches have been extensively used. The paper addresses the question of both robustness and efficiency of penalized model selection methods and proposes a data-driven weighted linear combination of convex loss functions, together with weighted L1-penalty. It is completely data adaptive and does not require prior knowledge of the error distribution. The weighted L1-penalty is used both to ensure…