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预防 HIV-1 母婴垂直传播的随机试验分析AI 解读

We analyze data from a randomized trial of breastfeeding versus formula feeding in HIV-1-infected mothers and their infants. Estimates of infant HIV-1-free survival and the timing of vertical transmission of HIV-1 are complicated by the fact that the infants' HIV-1 status at death may be unknown, the time of HIV-1 infection may be interval censored, and the tests used to detect HIV-1 infection in the infants may be less than 100% sensitive or specific. To address these…

预防 HIV-1 母婴传播随机试验的分析AI 解读

We analyze data from a randomized trial of breastfeeding versus formula feeding in HIV-1-infected mothers and their infants. Estimates of infant HIV-1-free survival and the timing of vertical transmission of HIV-1 are complicated by the fact that the infants' HIV-1 status at death may be unknown, the time of HIV-1 infection may be interval censored, and the tests used to detect HIV-1 infection in the infants may be less than 100% sensitive or specific. To address these…