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Using covariate-specific disease prevalence information to increase the power of case-control studies

利用协变量特定患病率信息提高病例对照研究功效

Public registration databases and large cohort studies provide vital information on disease prevalence at various levels of a risk factor. This auxiliary information can be helpful in conducting statistical inference in a new study. We aim to develop a statistical procedure that improves the efficiency of the logistic regression model for a case-control study by utilizing auxiliary information on covariate-specific disease prevalence via a series of unbiased estimating…

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Diagnostic measures for empirical likelihood of general estimating equations

一般估计方程经验似然的诊断度量

We develop diagnostic measures for assessing the influence of individual observations when using empirical likelihood with general estimating equations, and we use these measures to construct goodness-of-fit statistics for testing possible misspecification in the estimating equations. Our diagnostics include case-deletion measures, local influence measures and pseudo-residuals. Our goodness-of-fit statistics include the sum of local influence measures and the processes of…

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Analysis of least absolute deviation

最小绝对偏差分析

We develop a unified L1-based analysis-of-variance-type method for testing linear hypotheses. Like the classical L2-based analysis of variance, the method is coordinate-free in the sense that it is invariant under any linear transformation of the covariates or regression parameters. Moreover, it allows singular design matrices and heterogeneous error terms. A simple approximation using stochastic perturbation is proposed to obtain cut-off values for the resulting test…

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A diagnostic procedure based on local influence

基于局部影响的模型诊断程序

Cook's (1986) normal curvature measure is useful for sensitivity analysis of model assumptions in statistical models. However, there is no rigorous approach based on the normal curvature for addressing two fundamental issues: to assess the extent of discrepancy between an assumed model and the underlying model from which the data are generated, and to identify suspicious data points for which the discrepancy is most evident. Our purpose is to establish a theoretically sound…

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