Estimation and Validation of Ratio-based Conditional Average Treatment Effects Using Observational Data
利用观察数据估计与验证比值型条件平均处理效应
While sample sizes in randomized clinical trials are large enough to estimate the average treatment effect well, they are often insufficient for estimation of treatment-covariate interactions critical to studying data-driven precision medicine. Observational data from real world practice may play an important role in alleviating this problem. One common approach in trials is to predict the outcome of interest with separate regression models in each treatment arm, and…