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存在处理诱导混杂的中介分析：识别、半参数效率与四重稳健估计AI 解读

Natural mediation effects are often of interest when the goal is to understand a causal mechanism. However, most existing methods and their identification assumptions preclude treatment-induced confounders often present in practice. To address this fundamental limitation, we provide a set of assumptions that identify the natural direct effect in the presence of treatment-induced confounders. Even when some of those assumptions are violated, the estimand still has an…

多中介自然中介效应的分解、识别与多重稳健估计AI 解读

Summary Natural mediation effects are desirable estimands for studying causal mechanisms in a population, but complications arise in defining and estimating natural indirect effects through multiple mediators with an unspecified causal ordering. We propose a decomposition of the natural indirect effect of multiple mediators into individual components, termed exit indirect effects, and a remainder interaction term, and study the similarities to and differences from existing…