论文检索

《利用隐马尔可夫模型 knockoff 寻找基因》作者回复AI 解读

We are very grateful to the editors for the opportunity to expand and deepen the reflection on the possible advantages of a knockoff approach to genome-wide association studies. The discussants bring up a number of important points, related to either the knockoffs methodology in general or its specific application to genetic studies. In this rejoinder we offer some clarifications, mention relevant recent developments, and highlight a few remaining open problems. The model-X…

利用隐马尔可夫模型 knockoff 变量寻找关联基因AI 解读

Modern scientific studies often require the identification of a subset of explanatory variables. Several statistical methods have been developed to automate this task, and the framework of knockoffs has been proposed as a general solution for variable selection under rigorous Type I error control, without relying on strong modelling assumptions. In this paper, we extend the methodology of knockoffs to problems where the distribution of the covariates can be described by a…