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尖峰噪声协方差下高维多元回归的一般线性假设检验AI 解读

We consider the problem of testing linear hypotheses under a multivariate regression model with a high-dimensional response and spiked noise covariance. The proposed family of tests consists of test statistics based on a weighted sum of projections of the data onto the estimated latent factor directions, with the weights acting as the regularization parameters. We establish asymptotic normality of the test statistics under the null hypothesis. We also establish the power…

高维 Hotelling T² 检验的自适应推广AI 解读

We propose a two-sample test for detecting the difference between mean vectors in a high-dimensional regime based on a ridge-regularized Hotelling’s $T^{2}$. To choose the regularization parameter, a method is derived that aims at maximizing power within a class of local alternatives. We also propose a composite test that combines the optimal tests corresponding to a specific collection of local alternatives. Weak convergence of the stochastic process corresponding to the…

球面切向向量场的建模AI 解读

Physical processes that manifest as tangential vector fields on a sphere are common in geophysical and environmental sciences. These naturally occurring vector fields are often subject to physical constraints, such as being curl-free or divergence-free. We start with constructing parametric models for curl-free and divergence-free vector fields that are tangential to the unit sphere through applying the surface gradient or the surface curl operator to a scalar random…

单调轨迹动力学的非参数估计AI 解读

We study a class of nonlinear nonparametric inverse problems. Specifically, we propose a nonparametric estimator of the dynamics of a monotonically increasing trajectory defined on a finite time interval. Under suitable regularity conditions, we show that in terms of $L^{2}$-loss, the optimal rate of convergence for the proposed estimator is the same as that for the estimation of the derivative of a function. We conduct simulation studies to examine the finite sample…

全基因组关联研究中高维误设混合模型的分析AI 解读

We study behavior of the restricted maximum likelihood (REML) estimator under a misspecified linear mixed model (LMM) that has received much attention in recent genome-wide association studies. The asymptotic analysis establishes consistency of the REML estimator of the variance of the errors in the LMM, and convergence in probability of the REML estimator of the variance of the random effects in the LMM to a certain limit, which is equal to the true variance of the random…

线性时间序列的 Marčenko–Pastur 定律AI 解读

This paper is concerned with extensions of the classical Marčenko–Pastur law to time series. Specifically, $p$-dimensional linear processes are considered which are built from innovation vectors with independent, identically distributed (real- or complex-valued) entries possessing zero mean, unit variance and finite fourth moments. The coefficient matrices of the linear process are assumed to be simultaneously diagonalizable. In this setting, the limiting behavior of the…

含噪高维数据中稀疏主成分分析的极小极大界AI 解读

We study the problem of estimating the leading eigenvectors of a high-dimensional population covariance matrix based on independent Gaussian observations. We establish a lower bound on the minimax risk of estimators under the $l_{2}$ loss, in the joint limit as dimension and sample size increase to infinity, under various models of sparsity for the population eigenvectors. The lower bound on the risk points to the existence of different regimes of sparsity of the…

用于蛋白质组通路分析的正则化 Hotelling T² 检验AI 解读

Recent proteomic studies have identified proteins related to specific phenotypes. In addition to marginal association analysis for individual proteins, analyzing pathways (functionally related sets of proteins) may yield additional valuable insights. Identifying pathways that differ between phenotypes can be conceptualized as a multivariate hypothesis testing problem: whether the mean vector μ of a p-dimensional random vector X is μ0. Proteins within the same biological…

主成分限制最大似然估计量的一致性AI 解读

In this paper we consider two closely related problems: estimation of eigenvalues and eigenfunctions of the covariance kernel of functional data based on (possibly) irregular measurements, and the problem of estimating the eigenvalues and eigenvectors of the covariance matrix for high-dimensional Gaussian vectors. In [A geometric approach to maximum likelihood estimation of covariance kernel from sparse irregular longitudinal data (2007)], a restricted maximum likelihood…

高维变量选择与回归中的“预处理”AI 解读

We consider regression problems where the number of predictors greatly exceeds the number of observations. We propose a method for variable selection that first estimates the regression function, yielding a “preconditioned” response variable. The primary method used for this initial regression is supervised principal components. Then we apply a standard procedure such as forward stepwise selection or the LASSO to the preconditioned response variable. In a number of simulated…

监督主成分预测AI 解读

In regression problems where the number of predictors greatly exceeds the number of observations, conventional regression techniques may produce unsatisfactory results. We describe a technique called supervised principal components that can be applied to this type of problem. Supervised principal components is similar to conventional principal components analysis except that it uses a subset of the predictors selected based on their association with the outcome. Supervised…