论文检索

存在依赖性终止时复发事件数据的现有分析方法AI 解读

There has been a recent surge of interest in modeling and methods for analyzing recurrent events data with risk of termination dependent on the history of the recurrent events. To aid the future users in understanding the implications of modeling assumptions and modeling properties, we review the state of the art statistical methods and present novel theoretical properties, identifiability results and practical consequences of key modeling assumptions of several fully…

摘要暂缺

结果依赖型随访的纵向研究AI 解读

We propose Bayesian parametric and semiparametric partially linear regression methods to analyze the outcome-dependent follow-up data when the random time of a follow-up measurement of an individual depends on the history of both observed longitudinal outcomes and previous measurement times. We begin with the investigation of the simplifying assumptions of Lipsitz, Fitzmaurice, Ibrahim, Gelber, and Lipshultz, and present a new model for analyzing such data by allowing…

癌症预防研究中的生存数据模型AI 解读

Summary We propose a new parametric survival model for cancer prevention studies. The formulation of the model is in the spirit of stochastic modelling of the occurrences of tumours through two stages: initiation of an undetected tumour and promotion of the tumour to a detectable cancer. Several novel properties of the model proposed are derived. In addition, we examine the relationship of our model with the existing lagged regression model of Zucker and Lakatos. Also, we…

含治愈比例生存数据的新贝叶斯模型AI 解读

We consider Bayesian methods for right-censored survival data for populations with a surviving (cure) fraction. We propose a model that is quite different from the standard mixture model for cure rates. We provide a natural motivation and interpretation of the model and derive several novel properties of it. First, we show that the model has a proportional hazards structure, with the covariates depending naturally on the cure rate. Second, we derive several properties of the…

生存数据的半参数贝叶斯分析AI 解读

This review article investigates the potential of Bayes methods for the analysis of survival data using semiparametric models based on either the hazard or the intensity function. The nonparametric part of every model is assumed to be a realization of a stochastic process. The parametric part, which may include a regression parameter or a parameter quantifying the heterogeneity of a population, is assumed to have a prior distribution with possibly unknown hyperparameters.…

分组生存数据边际似然的最大化AI 解读

Grouped failure time data occur in studies where subjects are monitored periodically to determine whether failure has occurred in the intervening interval. Here the model under consideration is Cox's (1972, 1975) proportional hazards model, but the commonly used method of partial likelihood needs modification with grouped data due to a potentially large number of ties. This paper demonstrates how the Monte Carlo em algorithm (Wei & Tanner, 1990) can be used on grouped data…

多事件时间数据的半参数贝叶斯分析AI 解读

Multiple event time data (e.g., carcinogenic growths in different times and locations, multiple attacks of cardiac arrest) arise in various medical studies. A Bayesian analysis of such data based on proportional intensity model of multiple event time data is presented in this paper. The Bayesian structure is somewhat analogous to that used by Kalbfleisch in a proportional hazard model. An unobserved random frailty component is used in the proportional intensity model to take…