A Saturated Model for Analyzing Exchangeable Binary Data: Applications to Clinical and Developmental Toxicity Studies
分析可交换二元数据的饱和模型:临床与发育毒性研究应用
Correlated binary data occur very frequently in statistical practice. In many applications, it is reasonable to assume that data from the same cluster are exchangeable. Such data are commonly encountered in cluster sample surveys, teratological experiments, ophthalmologic and otolaryngologic studies, and other clinical trials. The standard methods of analyzing these data include the use of beta-binomial models and generalized estimating equations with third and fourth…