Estimating the HIV Vertical Transmission Rate and the Pediatric AIDS Incubation Period from Prospective Data
利用前瞻性数据估计HIV母婴传播率与儿童艾滋病潜伏期
This article considers the estimation of the rate of vertical human immunodeficiency virus (HIV) transmission and the pediatric acquired immune deficiency syndrome (AIDS) incubation period using data from birth cohort studies. Standard methods of analysis, which ignore children whose infection status is not established, may lead to biased estimates. Methods based on modeling the disappearance of HIV antibody or appearance of virus are inefficient, as they essentially rely on…