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高维遗传通路分析的统计推断AI 解读

Summary Genetic pathway analysis has become an important tool for investigating the association between a group of genetic variants and traits. With dense genotyping and extensive imputation, the number of genetic variants in biological pathways has increased considerably and sometimes exceeds the sample size $n$. Conducting genetic pathway analysis and statistical inference in such settings is challenging. We introduce an approach that can handle pathways whose dimension $p$…

比例风险回归的函数型 ANOVA 建模AI 解读

The logarithm of the relative risk function in a proportional hazards model involving one or more possibly time-dependent covariates is treated as a specified sum of a constant term, main effects, and selected interaction terms. Maximum partial likelihood estimation is used, where the maximization is taken over a suitably chosen finite-dimensional estimation space, whose dimension increases with the sample size and which is constructed from linear spaces of functions of one…

Triogram：自适应三角剖分模型AI 解读

In this article we introduce the Triogram method for function estimation using piecewise linear, bivariate splines based on an adaptively constructed triangulation. We illustrate the technique for bivariate regression and log-density estimation and indicate how our approach can be applied directly to model bivariate functions in the broader context of an extended linear model. The entire estimation procedure is invariant under affine transformations and is a natural approach…

Triogram 三角剖分样条模型AI 解读

In this article we introduce the Triogram method for function estimation using piecewise linear, bivariate splines based on an adaptively constructed triangulation. We illustrate the technique for bivariate regression and log-density estimation and indicate how our approach can be applied directly to model bivariate functions in the broader context of an extended linear model. The entire estimation procedure is invariant under affine transformations and is a natural approach…

多分类回归AI 解读

An automatic procedure that uses linear splines and their tensor products is proposed for fitting a regression model to data involving a polychotomous response variable and one or more predictors. The fitted model can be used for multiple classification. The automatic fitting procedure involves maximum likelihood estimation, stepwise addition, stepwise deletion, and model selection by the Akaike information criterion, cross-validation, or an independent test set. A modified…

预测振荡模式：随机场时空分解方法的综合AI 解读

Spatial-temporal decompositions of climatologic fields have been obtained using a range of techniques, including principal component analysis (PCA) and principal oscillation patterns (POPS). PCA decompositions are forced to be correlated to the original field, but they may not capture interesting aspects of temporal variation. On the other hand, POPS decompositions focus on temporal variation but are not forced to correlate to the field. Here we introduce a hybrid of these…

预测振荡模式：随机场时空分解方法的综合AI 解读

Spatial-temporal decompositions of climatologic fields have been obtained using a range of techniques, including principal component analysis (PCA) and principal oscillation patterns (POPS). PCA decompositions are forced to be correlated to the original field, but they may not capture interesting aspects of temporal variation. On the other hand, POPS decompositions focus on temporal variation but are not forced to correlate to the field. Here we introduce a hybrid of these…

摘要暂缺

风险率回归AI 解读

Linear splines and their tensor products are used to estimate the conditional log-hazard function based on possibly censored, positive response data and one or more covariates. An automatic procedure involving the maximum likelihood method, stepwise addition, stepwise deletion, and the Bayes Information Criterion is used to select the final model. The possible models contain proportional hazards models as a subclass, which makes it possible to diagnose departures from…

论条件自回归与内蕴自回归AI 解读

Gaussian conditional autoregressions have been widely used in spatial statistics and Bayesian image analysis, where they are intended to describe interactions between random variables at fixed sites in Euclidean space. The main appeal of these distributions is in the Markovian interpretation of their full conditionals. Intrinsic autoregressions are limiting forms that retain the Markov property. Despite being improper, they can have advantages over the standard…