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受限随机分配规则下的区间估计AI 解读

In comparing two treatments in a clinical trial, suppose that patients are assigned sequentially to treatments by a restricted randomization rule. Exact and approximate confidence intervals for treatment difference are derived without assuming that the study subjects were obtained by random sampling from a well-defined population. We show that, if there is a time trend among the responses of study subjects, one should not ignore the design in the analysis. All the procedures…

受限随机分配规则下的区间估计AI 解读

In comparing two treatments in a clinical trial, suppose that patients are assigned sequentially to treatments by a restricted randomization rule. Exact and approximate confidence intervals for treatment difference are derived without assuming that the study subjects were obtained by random sampling from a well-defined population. We show that, if there is a time trend among the responses of study subjects, one should not ignore the design in the analysis. All the procedures…