Marginalized Frailty-Based Illness-Death Model: Application to the UK-Biobank Survival Data
基于边际化脆弱性的疾病—死亡模型：英国生物样本库应用
The UK Biobank is a large-scale health resource comprising genetic, environmental, and medical information on approximately 500,000 volunteer participants in the United Kingdom, recruited at ages 40–69 during the years 2006–2010. The project monitors the health and well-being of its participants. This work demonstrates how these data can be used to yield the building blocks for an interpretable risk-prediction model, in a semiparametric fashion, based on known genetic and…