Nonparametric Residue Analysis of Dynamic PET Data With Application to Cerebral FDG Studies in Normals
动态 PET 数据的非参数残留函数分析:健康受试者脑部 FDG 研究
Kinetic analysis is used to extract metabolic information from dynamic positron emission tomography (PET) uptake data. The theory of indicator dilutions, developed in the seminal work of Meier and Zierler (1954), provides a probabilistic framework for representation of PET tracer uptake data in terms of a convolution between an arterial input function and a tissue residue. The residue is a scaled survival function associated with tracer residence in the tissue. Nonparametric…