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Collective Outlier Detection and Enumeration with Conformalized Closed Testing

基于共形化闭合检验的集体异常检测与计数

This paper develops a flexible distribution-free method for collective outlier detection and enumeration, designed for situations in which the presence of outliers can be detected powerfully even though their precise identification may be challenging due to the sparsity, weakness, or elusiveness of their signals. This method builds upon recent developments in conformal inference and integrates classical ideas from other areas, including multiple testing, locally most…

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Flexible control of the median of the false discovery proportion

错误发现比例中位数的灵活控制

Summary We introduce a multiple testing procedure that controls the median of the proportion of false discoveries in a flexible way. The procedure requires only a vector of p-values as input and is comparable to the Benjamini–Hochberg method, which controls the mean of the proportion of false discoveries. Our method allows free choice of one or several values of $ \alpha $ after seeing the data, unlike the Benjamini–Hochberg procedure, which can be very anti-conservative…

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Simultaneous directional inference

同时方向推断

Abstract We consider the problem of inference on the signs of n>1 parameters. We aim to provide 1−α post hoc confidence bounds on the number of positive and negative (or non-positive) parameters, with a simultaneous guarantee, for all subsets of parameters. We suggest to start by using the data to select the direction of the hypothesis test for each parameter; then, adjust the p-values of the one-sided hypotheses for the selection, and use the adjusted p-values for…

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On selection and conditioning in multiple testing and selective inference

多重检验与选择性推断中的选择和条件化

Summary We investigate a class of methods for selective inference that condition on a selection event. Such methods follow a two-stage process. First, a data-driven collection of hypotheses is chosen from some large universe of hypotheses. Subsequently, inference takes place within this data-driven collection, conditioned on the information that was used for the selection. Examples of such methods include basic data splitting as well as modern data-carving methods and…

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Only closed testing procedures are admissible for controlling false discovery proportions

控制错误发现比例的可容许程序必须采用闭合检验

We consider the class of all multiple testing methods controlling tail probabilities of the false discovery proportion, either for one random set or simultaneously for many such sets. This class encompasses methods controlling familywise error rate, generalized familywise error rate, false discovery exceedance, joint error rate, simultaneous control of all false discovery proportions, and others, as well as gene set testing in genomics and cluster inference in neuroimaging.…

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Simultaneous control of all false discovery proportions in large-scale multiple hypothesis testing

大规模多重检验中所有假设子集的错误发现比例同时控制

Summary Closed testing procedures are classically used for familywise error rate control, but they can also be used to obtain simultaneous confidence bounds for the false discovery proportion in all subsets of the hypotheses, allowing for inference robust to post hoc selection of subsets. In this paper we investigate the special case of closed testing with Simes local tests. We construct a novel fast and exact shortcut and use it to investigate the power of this approach…

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The sequential rejection principle of familywise error control

族错误率控制的序贯拒绝原理

Closed testing and partitioning are recognized as fundamental principles of familywise error control. In this paper, we argue that sequential rejection can be considered equally fundamental as a general principle of multiple testing. We present a general sequentially rejective multiple testing procedure and show that many well-known familywise error controlling methods can be constructed as special cases of this procedure, among which are the procedures of Holm, Shaffer and…

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