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用匹配自适应随机化推断重新评估激素替代疗法对心脏病的影响AI 解读

Matching is an appealing way to design observational studies because it mimics the data structure produced by stratified randomized trials, pairing treated individuals with similar controls. After matching, inference is often conducted using methods tailored for stratified randomized trials in which treatments are permuted within matched pairs. However, in observational studies, matched pairs are not predetermined before treatment; instead, they are constructed based on…

高维异质中介分析的检验功效增强AI 解读

Mediation models are widely used in many scientific areas to understand how an exposure variable impacts an outcome variable through an intermediate variable. In this article, we develop powerful inferential methods to analyze mediation effects in high-dimensional contexts with intercorrelated potential mediators in models with linear and generalized linear outcomes. We draw attention to heterogeneous mediation, and show that existing testing approaches based on the total…

平均处理效应局部化：合成控制中的投影方法AI 解读

Many real-world policies and business interventions require assessing short-term effects to inform timely decisions, even though most causal inference methods focus on long-term average treatment effects. In this article, we introduce average treatment effect localization (ATEL), which captures localized, short-term policy impacts in panel data settings with a single treated unit and provides early indicators of policy impact. To accommodate both time-varying and nonlinear…

通过模型平均实现多层网络迁移学习的框架AI 解读

Link prediction in multilayer networks is a key challenge in applications such as recommendation systems and protein-protein interaction prediction. While many techniques have been developed, most rely on assumptions about shared structures and require access to raw auxiliary data, limiting their practicality. To address these issues, we propose a novel transfer learning framework for multilayer networks using a bi-level model averaging method. A $K$-fold cross-validation…

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协变量自适应随机实验中混合效应模型的统计推断AI 解读

Recent clinical studies increasingly involve a long factor with many levels, e.g., investigation sites, resulting in a large number of strata that must be accounted for either through design or subsequent analysis. This complication has prompted concerns from the U.S. Food and Drug Administration (FDA, 2023) regarding the adequacy of standard statistical methods, whose performance may deteriorate, and their properties become unclear when the number of strata is relatively…

集体家庭消费中的规模经济AI 解读

ABSTRACT Browning et al. (2013) model collective‐household economies of scale in goods consumption by having each good be partly shared, instead of each good being public or private. We modify their model to achieve simple point identification and estimation of the economies of scale of consumption of each good, and we provide a new index of household level economies of scale. Our model has a linear form, permits households of varying composition, including children, and…

离散空间随机场的有向图模型混合AI 解读

Current approaches for modeling discrete-valued outcomes associated with spatially-dependent areal units incur computational and theoretical challenges, especially in the Bayesian setting when full posterior inference is desired. As an alternative, we propose a novel statistical modeling framework for this data setting, namely a mixture of directed graphical models (MDGMs). The components of the mixture, directed graphical models, can be represented by directed acyclic…

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结果选择下用于目标因果推断的协作表征AI 解读

Estimating causal effects with missing outcomes requires learning outcome, exposure, and selection models. Flexible propensity learners can predict treatment or missingness well while worsening target estimation by emphasizing instruments, weak-overlap regions, or variation unrelated to outcome-regression bias. We propose a collaborative representation-based targeted learning method for recovered average treatment effects under outcome selection. The method learns…

基于最优传输的稳定因果估计AI 解读

In observational studies, the overlap assumption, also called positivity, is frequently strained in practice. Limited overlap destabilizes widely used estimators such as inverse propensity weighting (IPW), whose variance depends on density ratios that explode as propensity scores approach zero or one. To address this challenge, we propose the Stable Transport Estimator (STE), an optimal transport-based approach for estimating average causal effects when overlap holds but…

基于秩的模型平均估计量用于平均处理效应AI 解读

Model averaging emerges as an attractive ensemble technique that strategically synthesizes all available information from potential candidate models to enhance estimation accuracy. Despite of having been widely practiced in various areas in biostatistics and economics, its application to causal inference is rather limited. We propose to estimate the average treatment effect (ATE) by forming the weighted combination of the robust rank-based estimators obtained from a series…

自适应实验中策略改进价值的推断AI 解读

In this paper, we develop an asymptotically normal estimator for the value of policy improvement (VPI) under adaptively collected data. This value, which is defined as the gap between the value of the best treatment policy in a class and that of a baseline policy, gauges whether or not it is worth deploying a personalized treatment policy. Building an estimator for the VPI is naturally more difficult than estimating the value of a fixed policy. This is because, in addition…

异质性高维分位数回归的全局推断AI 解读

Quantile regression has received considerable attention in high dimensional methodology due to its robustness and ability to accommodate heteroskedasticity. Despite this attention, current inferential methods for high dimensional quantile regression have significant limitations---only testing significance, testing at a single quantile at a time, or assuming homoskedasticity. To generalize the inferences that can be drawn in high dimensional quantile regression, we introduce…

社会网络数据中处理效应的识别与估计：当社会连接存在混杂时AI 解读

In observational network data, the adoption of a treatment and the formation of social ties often depend on the same characteristics that affect outcomes. We propose a generalized propensity score for each unit's effective treatment, built from a model for treatment assignment and a dyadic model for network formation, which may include latent node heterogeneity. The score is marginalized over the network given covariates rather than conditioned on the realized network, and…

随机试验的比较：试验参与效应与效应迁移AI 解读

Disagreements between randomized trials that address the same causal question pose challenges for the interpretation and synthesis of evidence. We sketch a causal framework for comparing the results of randomized trials that explicitly accommodates the possibility of trial engagement effects. Using counterfactual outcomes defined under joint interventions on treatment assignment and trial-related actions, we compare trial-native treatment effects with the effects transported…

重尾模型中的基于比率的因果发现AI 解读

In many complex systems, such as river networks and financial markets, extreme events propagate from causes to their effects, and the largest observations carry the most information about the underlying causal structure. Existing methods for causal discovery in extremes, however, are tailored to specific mechanisms, such as linear or max-linear models. This work develops causal discovery for heavy-tailed homogeneous structural causal models, a flexible class that contains…

记录链接存在歧义时的随机实验AI 解读

Randomized experiments are often linked to administrative data to measure outcomes, but coarse identifiers can leave multiple administrative records consistent with each experimental unit. We show that unbiased estimation of the sample average treatment effect is possible without resolving these ambiguous links or specifying an outcome model. Our key linkage requirement is that the true administrative outcome is contained among the candidate outcomes for each experimental…

复杂（准）实验设计下的简单标准误AI 解读

We develop standard errors for estimates of causal effects in settings where the distribution of treatment exposures is known but potentially exhibits complicated dependence patterns across units. Such dependence arises, for example, in settings with spillovers/interference across units or when the treatment assignment is spatially correlated. Our variance estimator generalizes several properties of the Neyman variance estimator for completely randomized experiments to…

面板数据分位数回归的GMM方法AI 解读

This paper develops a smoothed generalized method of moments (GMM) framework for panel quantile models with individual-specific fixed-effects and endogenous regressors. By smoothing the indicator in the quantile moment conditions and profiling out the individual effects through smoothed individual quantile restrictions, the proposed estimator can be implemented using standard GMM algorithms. We establish consistency, asymptotic normality, and feasible inference under weak…

潜在类别对处理效应的调节AI 解读

Many treatments have effects that plausibly vary by latent classes. For example, the effect of personalized video recommendations may be stronger for users who seek a new discovery than for users seeking to rewatch something familiar. In the context of user journeys on digital platforms, we can conceptualize user moods as dynamic latent states that lead to distinct action distributions. Because mood is unobserved, we infer it from a user's pre-treatment actions using a…

非精确匹配何时能在无需调整的情况下保证平衡与有效推断？AI 解读

One-to-one matching without replacement is a classical approach to constructing comparable treated and control samples in the design of observational studies. It pairs each treated unit with a distinct control while minimizing a covariate distance objective. With continuous covariates, the matched pairs generally remain inexact, which contributes to bias in downstream analysis. Its key theoretical properties, such as the resulting imbalance between matched pairs and when it…

用于处理效应估计的预测驱动数据融合AI 解读

Randomized controlled trials (RCTs) identify treatment effects without confounding but are often small, whereas observational studies (OBS) are large but may be confounded. Many estimators combining a small RCT with a large OBS have been developed for the average treatment effect (ATE) and the conditional ATE (CATE). However, existing ATE estimators either make assumptions on the OBS or do not borrow enough power from them. The CATE has been studied less than the ATE.…

面板信息矩阵检验AI 解读

The Information Matrix (IM) test is a natural specification check for likelihood-based models, yet cross-sectional implementations are often badly sized, confound neglected heterogeneity with distributional misspecification, and require third derivatives. We develop the panel information matrix (PIM) test for models with fixed effects. Explicit fixed effects isolate functional-form misspecification from time-invariant unobserved heterogeneity. Although the profile maximum…

克隆—删失—加权方法的形式化与一致性AI 解读

Target trial emulation has become a standard framework for causal inference from observational data. Within this paradigm, the clone-censor-weight (CCW) methodology provides a practical way to deal with complex treatment and adherence definitions when treatment regimes are not distinguishable at baseline. Despite its increasing use, the statistical interpretation of CCW remains limited. In this work, we formalize the CCW methodology from a statistical viewpoint based on…

重加权分布中选择直接原因的评分方法AI 解读

Scoring methods based on the Bayesian information criterion (BIC) are commonly used for model selection tasks such as choosing features in a regression model or learning directed acyclic graphs from data. In certain model classes, model selection based on the BIC is consistent. However, since the BIC is based on the observed likelihood function, it does not apply directly to reweighted distributions arising in causal inference, missing data, and domain shift applications.…