每日简报

面向空间转录组与遥感数据的空间正交因子模型AI 解读

Principal component analyses are often applied to spatial data towards inference on latent modes of spatial variation. These analyses are widespread across domains including spatial transcriptomics and environmental sciences, where the modes of spatial variation are represented by corresponding factors of gene expression or remotely sensed time series measurements. Many methods have been proposed for incorporating spatial information into a probabilistic PCA framework;…

利用稳定平衡权重对多种目标参数进行简便协变量调整AI 解读

Covariate adjustment can improve precision in estimating treatment effects in clinical trials, and regulatory guidance increasingly encourages its implementation. Despite its benefits, covariate adjustment can require advanced statistical techniques or tailored approaches for different estimands, which can deter its use in practice. To address this issue, we introduce a simplified approach to covariate adjustment using stable balancing weights that applies directly across…

SAUSS：有限因变量模型的无偏模拟得分随机逼近AI 解读

Multinomial choice models allow flexible substitution patterns but become computationally demanding with many alternatives or observations. With a fixed per-observation simulation budget, simulated maximum likelihood introduces simulation bias, while each optimization step requires a full-sample likelihood evaluation. We propose Stochastic Approximation with Unbiased Simulated Scores (SAUSS), an averaged stochastic approximation based on conditionally unbiased mini-batch…

函数型时间序列的频域自助法AI 解读

A frequency domain bootstrap procedure for functional time series is proposed and applied to the class of spectral mean operators. The procedure works by first generating independent pseudo periodogram operators across the positive Fourier frequencies using an estimator of the spectral density operator involved. Functional replicates of the spectral mean operators of interest are then generated. Through an additive, projection-based decomposition of the bootstrapped spectral…

部分识别离散响应模型的非参数贝叶斯推断AI 解读

This paper proposes a nonparametric Bayesian inference framework for partially identified discrete response models. The key observation is that these models map a reduced-form conditional choice probability to an identified set. Consequently, nonparametric Bayesian inference for the conditional probability mass function leads to Bayesian inference for the identified set. The inference framework nests conditional moment inequalities and linear systems with unknown…

二次型统计量的随机不变性检验及自相关应用AI 解读

Randomization testing with permutations is a very common nonparametric approach to hypothesis testing. However, randomization testing can be done with other group transformations including random rotations. In this work, we consider the problem of invariance in quadratic form statistics under a unified framework with closed form p-values. In particular, we propose a nonparametric variant of the classic Durbin-Watson test for testing for autocorrelation in time series data at…

FLEX-CP-DT：计数终点与时间趋势下的期中无效性分析AI 解读

Many large-scale phase III trials with recurrent event endpoints include a pre-planned interim analysis to evaluate early futility. Conditional power (CP), which quantifies the probability of achieving statistical significance at the final analysis given the interim data, is a commonly used tool to support such decisions. The standard negative binomial model with an offset term, widely adopted for analyzing recurrent events, implicitly assumes that event rates and treatment…

正则化高维加性张量自回归模型AI 解读

High-dimensional time series has diverse applications in econometrics and finance. Recent models for capturing temporal dependence have employed a bilinear representation for matrix time series, or the Tucker-decomposition based representation in case of tensor time series. A Tucker-decomposition based temporal effect is difficult to interpret on many occasions, along with its computational complexity due to the non-convex nature of the underlying optimization problem.…

处理—混杂反馈下电力需求的边际结构模型与连续处理自适应 LASSOAI 解读

Temperature is the most important meteorological driver of electricity demand, but its causal effect has not been estimated under the time-varying confounding that characterizes weather processes. Current temperature is associated with weather conditions, including precipitation, snow cover, and cloud cover, that also influence electricity demand, and past temperature shapes future weather, producing treatment-confounder feedback under which standard regression adjustment is…

混合对照试验的功效与样本量计算AI 解读

Hybrid controlled trials (HCTs) augment randomized controls with external controls (ECs) to address practical challenges in randomized controlled trials (RCTs) and improve statistical power in settings such as rare diseases, oncology, and pediatrics. However, prospective sample-size determination is challenging because the required RCT sample size depends on the comparability of ECs with RCT controls, which are unavailable at the planning stage. We propose a 5+3 design for…

提高检验功效的统一自适应富集设计AI 解读

Randomized controlled trials (RCTs) are the gold standard for evaluating treatment effects, but fixed eligibility criteria and enrollment decisions can be inefficient, especially when treatment effects vary across patient subpopulations. Adaptive enrichment trials update enrollment using interim data to improve efficiency. Enrichment methods are developed for two settings: prespecified subgroups, and continuous covariates where enrollment is guided by a learned cutoff. Many…

DIRECT：分解视觉内容分析中的受众偏好与创作效应AI 解读

Which visual choices make a post perform better? A growing literature answers this question with pooled coefficients estimated across many creators, which platforms translate into creative recommendations. We show that these coefficients blend two distinct patterns that can point in opposite directions for the same attribute. The first, audience preference, arises because creators who favor a style attract differently composed audiences, so their posts perform differently…

受试者内实验的分析：识别、检验与敏感性AI 解读

Recent work encourages political scientists to move from post-only toward within-subject designs for improved precision from repeated measurements. We formalize a potential-outcomes framework for two-period within-subject designs that allows for unequal allocation and heterogeneous treatment and carryover effects. We characterize the pooled estimator and evaluate the carryover test used to justify pooling. We find: first, pooling identifies the average treatment effect only…

基于因果图的方差分解：何时解释方差意味着因果作用AI 解读

Recursive application of the law of total variance decomposes the marginal variance of an outcome into components attributed to explanatory variables and a residual component. The resulting decomposition depends on the chosen conditioning order, and its components do not in general have causal interpretations. We develop a graph-based framework for defining causal counterparts of ordered variance components and establishing their identification from observed data. Under…

双向不可观测异质性的非参数识别AI 解读

We study identification of two-way unobserved heterogeneity in the nonparametric panel regression $G_{it}=g(α_i,γ_t)+\varepsilon_{it}$, where identification of the latent types reduces to constructing identified, \emph{injective} proxies for them. To this end we consider the singular value decomposition (SVD) of the bivariate regression function $g(α,γ)$ on a product domain $Ω_α\timesΩ_γ$, whose left singular functions $\{u_r\}$ serve as proxies for the unobserved…

结合协变量调整与次要终点信息提高随机试验精度AI 解读

Background/Aims: Adjustment for prognostic baseline covariates can improve precision in randomized trials. Previous work has shown that jointly modeling primary and secondary endpoints can yield additional precision by borrowing information across endpoints. We investigated whether these approaches can be combined to achieve efficiency gains beyond those obtained through covariate adjustment alone. Methods: We extended a previously proposed one-factor structural equation…

厚尾与随机波动率下规范化向量自回归预测软件的设计AI 解读

We present a suite of R packages for macroeconomic forecasting that leverages advanced Bayesian, structural, multivariate, dynamic, hierarchical, non-linear, and non-Gaussian models. The suite enables both structural and predictive analyses, and is adapted to time series data across various types, dimensions, and sampling frequencies. Each additional feature increases computational complexity. To address this challenge, our software design incorporates a carefully curated…

SCAN：通过自适应非参数推断依次检测变点AI 解读

Modern time series are often long, serially dependent, and non-stationary. Existing change-point methods either target specific changes or become computationally intensive when using nonparametric costs on long series. Many also require thresholds to be carefully calibrated under serial dependence. We introduce SCAN, an offline method for detecting multiple distributional change-points in long, serially dependent univariate time series. SCAN compares adjacent windows using…

因果—非因果状态空间模型与金融泡沫建模AI 解读

In this paper, we study causal non-causal state space models to model time series characterised by a local explosive increase followed by a sharp decrease such as stock prices. To motivate the use of causal non-causal state space models, we show that the causal non-causal convolution autoregressive model introduced by Gourieroux and Zakoian (2017) can be consistent with the rational expectations stock price model. As in a causal state space model, a central question is how…

簇规模饱和与 g 计算：信息性簇规模下的稳健因果推断AI 解读

Cluster randomized trials (CRTs) can exhibit informative cluster sizes (ICS) where cluster size is associated with outcomes and/or treatment effects. Under ICS, the individual and cluster-average treatment effects (iATE, cATE) can diverge, and the conventional linear mixed-effects model (LMM) and generalized estimating equation (GEE) with an exchangeable working correlation can produce data-dependent weighted contrasts that are not consistent for either estimand. In these…

通过惩罚最小二乘实现一步式分组因子分析AI 解读

In this article, we revisit the problem of group factor analysis and propose a one-step penalized least squares method to estimate the factor loadings and factors in large-dimensional group factor models, offering a distinct alternative to the conventional two-step principal component approach. Our procedure originates from the equivalence between the group factor structure and the carefully tailored identification conditions. Leveraging this insight, we develop a tricky…

度量空间时间序列的在线分布变化检测AI 解读

We propose an online testing framework for detecting distributional changes in serially dependent data with values in a separable metric space. Based on two-sample $U$-statistics, the framework encompasses sequential analogs of energy distance and maximum mean discrepancy (MMD) procedures while accommodating temporal dependence. We establish asymptotic theory for finite and open-ended monitoring horizons that characterizes the full asymptotic run-length distribution under $H_0$…

修正局部错设的 GMM：经验贝叶斯方法AI 解读

Econometric models offer parsimonious but inexact approximations to data-generating processes. This paper studies the generalized method of moments (GMM) when exchangeable specification errors of order $n^{-1/2}$ contaminate the moment conditions. I develop estimators for the mean and variance of these specification errors, establishing their consistency in an asymptotic framework where the number of overidentifying restrictions grows with the sample size. These…

预测误差为何不足以评价因果估计中的辅助函数预测AI 解读

Prediction error is widely used to evaluate nuisance-function estimators in causal inference, but its relationship with causal estimator performance may differ across performance measures. We studied this question in a partially linear model using Monte Carlo simulations. We compared ordinary least squares (OLS), generalized additive models (GAMs), XGBoost, and Double Machine Learning with XGBoost (DML-XGBoost), evaluating nuisance-function prediction error, bias, RMSE, and…