每日简报

共同冲击下固定 T 的动态空间面板模型AI 解读

We study a dynamic spatial panel model with observed regressors, interactive effects, and contemporaneous and lagged dependence in a large-$N$, fixed-$T$ framework. The spatial model constitutes an $N$-dimensional simultaneous-equations system. In this $N$-equation view, the interactive effects introduce $N$ unit-specific loading vectors. Estimating them individually when $T$ is fixed creates the type of incidental-parameters problem underlying Nickell bias. We use the $N$-eq…

多元时空回归：惩罚模型选择与实证应用AI 解读

This paper develops the statistical foundations of a multivariate general nesting spatio-temporal (MGNST) regression framework for analyzing spatial, temporal, and cross-equation dependence among responses. Four parameter matrices represent spatial lag dependence, spatial error dependence,temporal autoregression, and contemporaneous error covariance. Their off-diagonal elements allow dependence to propagate within and across responses. Matrix restrictions yield eleven…

无序对空间上的协方差核：理论与网络数据应用AI 解读

Many scientific problems are relational: the quantity of interest is a connection between two objects, while information about similarity is available for the objects themselves. We develop a covariance framework for unordered relationships that transfers object-level geometry to the relations they form while preserving endpoint identity and invariance to ordering. Building on symmetric pairwise-kernel representations, we develop theory for the loop-free domains used in…

部分干扰下用于倾向得分估计的混合效应结果自适应 LassoAI 解读

Interference occurs when one individual's treatment or exposure affects another individual's outcome. In particular, we assume partial interference, where individuals are divided into groups such that there is no interference between individuals in different groups. In observational studies, inverse probability weighting (IPW) based on propensity scores is often used for causal effect estimation. However, under partial interference, the group-level propensity score must be…

条件随机分组下同伴效应的估计与推断AI 解读

Empirical studies of peer effects often exploit conditional random assignment to peer groups within urns. We develop a GMM framework for estimation and inference in this setting. The framework separately identifies endogenous and contextual peer effects and nests tests of random peer-group assignment as a special case. It permits unknown heteroskedasticity and corrects finite-urn bias in variance estimation. Its asymptotic theory allows the number of peer groups to grow…

生存结局治疗效应的随机化推断AI 解读

The log-rank test and Kaplan--Meier plot are standard tools for analyzing time-to-event data in randomized clinical trials, yet neither provides a summary of the magnitude of the treatment effect. Practitioners typically fill this gap by reporting a hazard ratio from a Cox proportional-hazards model or an acceleration factor from an accelerated failure time (AFT) model, but both require assumptions beyond those needed for the log-rank test or Kaplan--Meier estimator. We…

NP-LEAP：借用历史数据的非参数潜在可交换性先验AI 解读

Bayesian dynamic borrowing (BDB) methods leverage historical data to reduce treatment effect uncertainty, yet existing approaches rely on parametric outcome models susceptible to misspecification. We propose the nonparametric latent exchangeability prior (NP-LEAP), an outcome-agnostic, assumption-lean framework to borrow information from historical data. The NP-LEAP performs individual-level exchangeability assessment, inducing Bayesian model averaging over all possible…

临床试验序贯多重插补：仅有基线数据的早期退出者扩展AI 解读

Under the ICH E9 (R1) addendum, treatment policy strategies for intercurrent events target the treatment effect regardless of treatment discontinuation. Sequential multiple imputation (MI) models that condition each visit's imputation on discontinuation status or pattern reduce bias relative to mixed models and standard MI, but require every subject to contribute at least one post-baseline observation, an assumption violated by subjects who withdraw before any post-baseline…

后验漂移与潜在隐藏混杂下的试验证据迁移AI 解读

Randomized trials provide internally valid treatment-effect evidence, but trial participants may not represent the target population. In contrast, observational studies are often closer to the target population, but their treatment assignment may be affected by possible hidden confounding. We develop a robust posterior-drift framework for estimating the average treatment effect in an observational target population when exact conditional-effect transportability may fail. The…

实验设计的极限：超越低维的协变量平衡AI 解读

We study how fast experimental designs can approach the semiparametric efficiency bound in finite samples, as measured by the excess variance of unadjusted treatment effect estimation. We prove an impossibility theorem: under weak conditions, no design can approach the variance bound uniformly over smooth outcome models unless covariate dimension $d \ll \log n$. Even in experiments with thousands of units, this permits only a handful of covariates. Motivated by this, we…

中断时间序列的因果中介分析：稳定中介加权及车辆排放政策应用AI 解读

Population-level policies are introduced at a fixed time and evaluated from a single series of aggregate outcomes, and the interrupted time series design estimates the total shift in an outcome after the intervention. When the policy is expected to act through a measurable pathway, the total effect is less informative than its decomposition into direct and indirect effects. We formulate causal mediation for a single interrupted time series and study stabilized mediator…

质心参照马氏匹配：大规模观察研究的因果推断框架AI 解读

Matching for causal inference can be computationally expensive at scale and can silently change the target population when overlap is limited. We propose Centroid-Referenced Mahalanobis Matching (CRM), which replaces global pairwise search with stratified sampling in two reference coordinates: each unit's Mahalanobis distance from the treated centroid and its Fisher coordinate along the treated-control mean shift. All covariates enter through the treated covariance geometry;…

用于季节性传染病干预因果评估的贝叶斯疫情对齐AI 解读

Seasonal infectious-disease interventions are commonly evaluated with interrupted time-series or pre--post designs that align epidemics by calendar week. When epidemic onset, speed or peak timing differs between seasons, such comparisons confound a shift in epidemic phase with a change in disease burden. We propose a Bayesian causal count model in which season-specific affine transformations map calendar time to a latent epidemic clock, and intervention effects are estimated…

不要丢弃单例：独立流失下配对实验的有效推断AI 解读

Pairwise randomization can yield substantial efficiency gains in experiments. Yet methodological guidance cautions against pairwise randomization, especially in settings with attrition, partly because common practices for estimation (i.e., pair fixed effects) imply discarding data from incomplete pairs thus exacerbating data loss from attrition. This practice of dropping incomplete pairs reduces statistical power of tests as well as precision of estimates, in paired…

协变量分布迁移下连续处理效应的因果推广AI 解读

Average dose-response functions are widely used to summarize causal effects of continuous treatments, but most existing methods assume that the observed sample represents the target population. We study a covariate-shift setting in which covariates, treatment, and outcome are observed in a labelled source sample, while only covariates are observed in the target sample. We develop a two-sample local polynomial regression framework based on pseudo-outcomes that use source…

诊断测试与人工智能医疗器械的因果评估：效应修饰与信息增强决策AI 解读

Diagnostic medical tests and devices provide useful information for evaluating the potential benefits and risks of therapeutic treatments. However, unlike treatments, their impact on health outcomes is generally indirect because measuring diagnostic information typically does not itself affect patient outcomes, which complicates evaluation of their effectiveness. In this work, we develop a causal inference approach for evaluating diagnostic tests by distinguishing…

鞅 R 学习器：事件时间结果的时变异质性治疗效应估计AI 解读

Biological research and clinical evidence suggest that treatment response may vary substantially along characteristics, such as comorbidities, genetic variants, environmental, or socio-economic factors. Future precision medicine requires accurate assessment of heterogeneous treatment effects (HTE) to guide optimal clinical decisions at the individual level. We introduce a functional score framework that extends the traditional estimating equations for survival data to…

非恒定效应因果加性模型中的工具变量集合有效性检验AI 解读

Instrumental variable (IV) methods are powerful for causal effect estimation with unmeasured confounding, but in practice researchers often face a set of candidate IVs whose validity is difficult to determine from observational data. This paper studies the problem of testing the validity of IV sets under Causal Additive Models with Non-Constant Effects (CAM-NCE). To address this problem, we propose a testable condition, termed the Cross Auxiliary-based independence Test…

分类处理下个体化处理规则的部分识别学习AI 解读

We develop a partial identification learning framework for individualized treatment rules (ITRs) with categorical treatments, outcomes, and instrumental variables. Rather than relying on strong causal assumptions required for point identification, our framework leverages causal bounds to characterize the optimal treatment decision. Existing methods for ITR optimization under partial identification are largely restricted to binary treatment settings and the bounds derived by…

病例对照研究中基于倾向得分的因果推断AI 解读

Propensity score methods for causal inference are increasingly being used in cohort and experimental designs, but their development and uptake in outcome-dependent sampling schemes, such as case-control studies, remains limited. Case-control studies involve the sampling of individuals with and without an outcome of interest with the goal of estimating the effects of past exposures. When the design is observational, statistical adjustment for confounding bias is necessary. In…

多方法因果证据综合：以跨方法趋同证据排序候选驱动因素AI 解读

Practitioners inferring causality from observational data usually rely on a single method and treat its output as causal truth. Recent tools select an optimal method for a dataset, and recent ensembles aggregate multiple causal-discovery algorithms into one graph, but little work pools evidence across different mathematical traditions, including non-causal ones. We present Multi-Method Causal Evidence Synthesis (MCES), a framework that ranks which candidate drivers in an…

靶向深度生存对比：神经网络下处理特定生存收益的有效推断AI 解读

Neural survival models are increasingly asked to support counterfactual claims---how much a treatment would change survival in a population---rather than only prognostic risk scores. Answering such questions from observational data requires valid inference for treatment-specific survival contrasts under confounding and covariate-dependent censoring, targets for which standard deep survival estimators are biased and provide no honest uncertainty. We propose Targeted Deep…

让时间提供信息：中断时间序列的识别与高斯过程估计AI 解读

We study causal inference in interrupted time series designs where a treatment affects every unit simultaneously, so that the contemporaneous controls used by difference-in-differences and synthetic control are unavailable and the counterfactual must be extrapolated from a unit's own pre-treatment history. We establish identification within the potential outcomes framework and estimate the counterfactual by Gaussian process regression. Rather than committing to a single…

利用 SIMEX 估计真实效应量分布AI 解读

Large-scale online experimentation produces noisy effect estimates, which can overstate gains and complicate decisions about launches and testing policies. We propose a nonparametric method based on SIMulation-EXtrapolation (SIMEX) to estimate the latent distribution of true effects from estimated average treatment effects with known variances. The method evaluates quantiles after adding progressively more simulated measurement noise and extrapolates the resulting inverse…