每日简报

中介变量受检测定量下限左删失时的因果间接效应评估AI 解读

Causal mediation analysis is essential for disentangling the mechanisms by which investigational therapeutic and preventive agents impact clinical outcomes. However, the measurement of biological mediators is often subject to left-censoring by technical measurement limitations, most commonly an assay's limit of quantification. This form of censoring can pose severe challenges for both identification and estimation of causal mediation estimands, particularly when the…

因果中介敏感性分析：桥接得分、尖锐敏感性界限与校准AI 解读

Causal mediation analysis decomposes the total treatment effect into a portion operating through a hypothesized mediator and a residual direct portion. Identification of natural direct and indirect effects typically rests on the mediator stage of sequential ignorability, which cannot be empirically verified and requires explicit sensitivity analysis. We formulate the \emph{bridge score}, a mediator-stage balancing score, as a low-dimensional vector formed from the two…

通过混合分布学习处理分类未观测混杂的因果推断AI 解读

Unobserved confounding is a fundamental challenge for estimating causal effects. To address unobserved confounding, recent literature has turned to two different approaches -- proxy variables and the use of multiple treatments. The first approach, commonly referred to as proximal causal inference, requires proxies to be assigned to specific asymmetric roles: treatment-inducing proxies (negative control exposures), variables that act as common causes of the treatment and…

分组数据下动态收入分布的贝叶斯状态空间建模与反事实分析AI 解读

Grouped income data contain only limited information about the evolution of income distributions over time. This paper develops a Bayesian state-space model for the generalized beta distribution of the second kind (GB2) to estimate dynamic income distributions using repeated grouped income data. By borrowing information across adjacent periods through the latent GB2 parameters, the proposed framework improves estimation precision relative to independent cross-sectional…

小样本临床试验中协变量调整风险差的评估AI 解读

Binary endpoints are common in clinical trials and conditional odds ratios have traditionally been used to assess treatment effects. However, the interpretation of odds ratios is difficult, they are non-collapsible, and conditional odds-ratios obtained from regression models additionally rely on modeling assumptions in order to be a relevant overall summary measure for the trial. As an alternative, risk differences have gained increasing prominence as a more interpretable,…

固定阶数 PCA：因子数量高估时的理论AI 解读

We develop asymptotic theory for principal component analysis (PCA) of a high-dimensional factor model in which the working dimension $R$ is fixed and only required to satisfy $R \ge r$, where $r$ is the true number of factors. Building on anisotropic local laws from random matrix theory, we show that the ``extra'' empirical eigencomponents beyond the $r$-th are asymptotically noise-governed, incoherent, and nearly orthogonal to the factor loadings. We introduce two…

一类实验设计的渐近效率界AI 解读

We consider an experimental design setting in which units are assigned to treatment after being sampled sequentially from an infinite population. We derive asymptotic efficiency bounds that apply to data from any experiment that assigns treatment as a (possibly randomized) function of covariates and past outcome data, including stratification on covariates and adaptive designs. For estimating the average treatment effect of a binary treatment, our results show that no…

检验观测数据中因果效应的识别AI 解读

This study demonstrates the existence of a testable condition for the identification of the causal effect of a treatment on an outcome in observational data, which relies on two sets of variables: observed covariates to be controlled for and a suspected instrument. Under a causal structure commonly found in empirical applications, the testable conditional independence of the suspected instrument and the outcome given the treatment and the covariates has two implications.…

从观测数据中学习因果分析所需的控制变量与工具变量AI 解读

This study introduces a data-driven, machine learning-based method to detect suitable control variables and instruments for assessing the causal effect of a treatment on an outcome in observational data. Our approach tests the joint existence of instruments, which are associated with the treatment but not directly with the outcome (at least conditional on observables), and suitable control variables, conditional on which the treatment is exogenous, and learns the partition…

增强大语言模型的因果推理：用于精准微调的因果归因模型AI 解读

This paper introduces a causal attribution model to enhance the interpretability of large language models (LLMs) and improve their causal reasoning abilities via precise fine-tuning. Despite LLMs' proficiency in diverse tasks, their reasoning processes often remain black box, and thus restrict targeted enhancement. We propose a novel causal attribution model that utilizes "do-operators" for constructing interventional scenarios, allowing us to quantify the contribution of…

彩色弹球：面向共形预测条件保证的密度加权分位数回归AI 解读

Although conformal prediction provides robust marginal coverage guarantees, achieving reliable conditional coverage for specific inputs remains challenging. While exact distribution-free conditional coverage is impossible with finite samples, recent work has focused on improving the conditional coverage of standard conformal procedures. Distinct from approaches that target relaxed notions of conditional coverage, we directly target the mean squared error of conditional…

无须结构方程的非参数工具变量分析：无精确解逆问题的泛函去偏推断AI 解读

We consider debiased inference on finite-dimensional functionals of infinite-dimensional least-squares solutions to inverse problems as a way to avoid having to assume exact solutions exist. Such assumptions are substantive and not innocuous, and their failure may imperil inference when we impose them on the statistical model. Our approach instead allows us to conduct inference on a quantity that is defined regardless of solutions existing and coincides with the usual…

基于贝叶斯非参数联合模型的连续时间纵向与生存数据因果中介分析AI 解读

Observational cohort data is an important source of information for understanding the causal effects of treatments on survival and the degree to which these effects are mediated through changes in disease-related risk factors. However, these analyses are often complicated by irregular data collection intervals and the presence of longitudinal confounders and mediators. We propose a causal mediation framework that jointly models longitudinal exposures, confounders, mediators,…

TEA-Time：跨时间迁移处理效应AI 解读

Treatment effects estimated from a randomized controlled trial are local not only to the study population but also to the time at which the trial was conducted. The literature on generalizing experimental findings to new populations is extensive, yet transporting effects across time has received far less attention, and even defining the target estimand is nonobvious. We formalize the transported average treatment effect under a separable temporal effects assumption, derive…

单变量与双变量结局的简便分布双重差分估计量AI 解读

We provide a simple distribution regression estimator for treatment effects in the difference-in-differences (DiD) design. Our procedure is particularly useful when the treatment effect differs across the distribution of the outcome variable. Our proposed estimator easily incorporates covariates and, importantly, can be extended to settings where the treatment potentially affects the joint distribution of multiple outcomes. Our key identifying restriction is that the…

固定匹配数匹配估计量的极限定理AI 解读

This paper re-examines the limit theorems of Abadie and Imbens for nearest-neighbor matching estimators of average treatment effects with a fixed number of matches. We establish, for the first time, a non-normalized central limit theorem (CLT) with an explicitly calculated limiting variance. The key ingredients are to prove the convergence of the normalizing statistic appearing in the CLT of Abadie and Imbens to its mean, and to calculate the closed form of the limit of this…

考虑未来时的个体反应估计AI 解读

We propose an approach to estimate how individuals' expectations influence their responses to a counterfactual change. The approach relies on average partial effects, which recover counterfactual impacts under conditions that we specify. We propose a three-step estimation method that relies on panel data on subjective expectations. We illustrate our approach in a model of consumption and saving, focusing on the impact of an income tax that not only changes current income but…

疫苗效力衰减的简便高功效检验AI 解读

Determining whether vaccine efficacy wanes is important for individual and public decision making. Yet, quantification of waning is a subtle task. The classical approaches cannot be interpreted as measures of declining efficacy unless we impose unreasonable assumptions. Recently, formal causal estimands designed to quantify vaccine waning have been proposed. These estimands can be bounded under weaker assumptions, but the bounds are often too wide to make claims about the…

不完备物理模型下异方差随机动力系统的因果发现AI 解读

Causal discovery is a data-driven paradigm for analyzing complex systems, while physics-based models, such as ordinary differential equations (ODEs), provide mechanistic structure for real-world dynamical processes. Integrating these paradigms can improve identifiability, stability, and robustness. However, real dynamical systems often exhibit cyclic interactions and nonstationarity, whereas many causal discovery methods rely on acyclicity, stationarity, or equilibrium…

少量处理单位情形下的统计推断AI 解读

In many causal inference applications, only one or a few units (or clusters of units) are treated. An important challenge in such settings is that standard inference methods relying on asymptotic theory may be unreliable, even with large total sample sizes. This survey reviews and categorizes inference methods designed to accommodate few treated units, considering cross-sectional and panel data methods. We discuss trade-offs and connections between different approaches. In…

可能非连续结局下处理组的分位数与分布处理效应AI 解读

Applied Difference-in-Differences studies often involve outcomes that are discrete, mixed, censored, or otherwise non-continuously distributed, while policy questions frequently concern distributional effects rather than mean effects alone. This paper develops a distributional DiD framework for identifying and conducting uniform inference on distribution and quantile treatment effects on the treated in such settings under stated identifying and regularity conditions.…

利用产品发布数据重新评估因果估计方法AI 解读

Recent developments in causal machine learning methods have made it easier to estimate flexible relationships between confounders, treatments and outcomes, making unconfoundedness assumptions in causal analysis more palatable. How successful are these approaches in recovering ground truth baselines? In this paper we analyze a new data sample including an experimental rollout of a new feature at a large technology company and a simultaneous sample of users who endogenously…

含未观测因果路径与后门路径的因果加性模型AI 解读

Causal additive models provide a tractable yet expressive framework for causal discovery in the presence of hidden variables. When unobserved backdoor or causal paths exist between two variables, their causal relationship is often unidentifiable under existing theories. We establish sufficient conditions under which causal directions can be identified in many such cases. These conditions rely on new characterizations of regression sets to determine independence among…

通过隐含干预进行因果推断AI 解读

In the context of having an instrumental variable, the standard practice in causal inference begins by targeting an effect of interest and proceeds by formulating assumptions enabling its identification. We turn this around by adhering to the interventions the observational distribution allows to identify, rather than starting with a desired causal estimand and imposing untestable conditions. The randomization of an instrument and its exclusion restriction define a class of…