每日简报

随机化后伴随用药差异下的生存结局处理效应估计AI 解读

In placebo-controlled randomized trials, the post-randomization use of concomitant medications may be higher in the placebo arm than in the treatment arm. This may dilute the full benefits of the randomized drug as estimated by the intention-to-treat analysis. We focus on cardiovascular outcomes trials in type-2 diabetes patients of glucose-lowering treatments where patients in the placebo arm are more likely to add other glucose-lowering agents with established…

RepFlow：用于因果效应估计的表示增强流匹配AI 解读

Estimating causal effects from observational data has become increasingly critical in diverse fields including healthcare, economics, and social policy. The fundamental challenge in causal inference arises from the missing counterfactuals and the selection bias. Existing methods are largely limited to point estimates and lack the capacity for distribution modeling. In this work, we propose RepFlow, a novel framework that formulates causal effect estimation as a joint…

This paper develops efficient GMM estimation under misspecified moment conditions. The influence function of the standard GMM estimator under misspecification depends on both the moment conditions and their Jacobian, motivating a new class of estimators based on augmented, recentered moment conditions. Standard GMM is a special case and generally suboptimal. By optimally weighting the augmented system, we obtain a misspecification-efficient (ME) estimator with the smallest…

TabCF：利用表格基础模型进行分布控制函数估计AI 解读

Instrumental variable (IV) and control function (CF) methods are powerful tools for causal effect estimation in the presence of unmeasured confounding, yet most existing approaches target only mean effects and/or demand substantial fitting and tuning effort. In this paper, we introduce a simple method, TabCF, for control function regression using tabular foundation models, which enables accurate, fast, identification-transparent, and tuning-light causal estimation of…

随机因果有向无环图的拓扑排序判据AI 解读

Random directed acyclic graphs (DAGs) based on imposing an order on Erdős-Rényi and scale free random graphs are widely used for evaluating causal discovery algorithms. We show that in such DAGs, the set of nodes reachable via open paths, termed relatives, increases monotonically along the causal order. We assess the prevalence of this pattern numerically, and demonstrate that it can be exploited for causal order recovery via sorting by the estimated number of relatives. We…

去偏机器学习中的协变量平衡与 Riesz 回归应由 Neyman 正交得分指导AI 解读

This position paper argues that, in debiased machine learning, balancing functions should be derived from the Neyman orthogonal score, not chosen only as functions of covariates. Covariate balancing is effective when the regression error entering the score can be represented by functions of covariates alone, and it is the natural finite-dimensional approximation for targets such as ATT counterfactual means. For ATE estimation under treatment effect heterogeneity, however,…

具有双向未观测异质性的线性回归推断AI 解读

We develop a general estimation and inference procedure for the common parameters in linear panel data regression models with nonparametric two-way specification of unobserved heterogeneity. The procedure takes as input any first-step estimators of the nonparametric regression function and the fixed effects and relies on two key ingredients: First, we develop moment conditions for the common parameters that are Neyman orthogonal with respect to the nonparametric regression…

两阶段自适应富集设计中的无偏估计AI 解读

Recent advances in biomedical research have identified an increasing number of biomarkers associated with heterogeneity in patient responses to medical treatments. When a treatment is suspected to benefit certain patient subpopulations, adaptive enrichment designs may be more efficient and ethical. In such designs, an interim analysis is incorporated during the trial to select patient subpopulations for which the experimental treatment appears promising, according to…

DARTS：预算受限序贯实验中的预后协变量选择AI 解读

Randomized controlled trials typically assume that prognostic covariates are known and available at no cost. In practice, obtaining high-dimensional pretreatment data is costly, forcing a trade-off between covariate-adaptive precision and a measurement budget. We introduce Dynamic Adaptive Rerandomization via Thompson Sampling (DARTS), which treats covariate acquisition as a sequential optimization problem embedded within a design-based causal inference task. A budgeted…

改进二元结局协变量调整的方差估计AI 解读

Covariate adjustment is a general method for improving precision when estimating treatment effects in randomized trials and is recommended by the FDA in its 2023 guidance when baseline variables are prognostic for the primary outcome. We focus on a method highlighted in that guidance called ``standardization" (or ``g-computation") for estimating the marginal treatment effect. We address the question of how to reliably estimate variance for binary outcomes when marginal…

Causal EpiNets：利用认知神经网络进行精度校正的个体因果界推断AI 解读

Individual treatment effects are not point-identified from data. The Probability of Necessity and Sufficiency (PNS) circumvents this limitation by characterizing individual-level causality through intersection bounds derived from combined experimental and observational data. In finite samples, however, standard plug-in estimators systematically fail: they violate structural probability constraints and suffer from extremum bias induced by max-min operators, yielding…

比例时间序列的 Beta-GAM 隐 Markov 模型AI 解读

We propose a hidden Markov model for univariate proportion time series taking values in (0,1), where regime switching captures latent structural changes and the emission distribution belongs to the Beta family. In each latent state, the Beta mean is linked to covariates through a generalized additive model (GAM) with spline-based smooth functions, while the Beta precision is state-specific, enabling flexible modeling of both nonlinear covariate effects and regime-dependent…

多步条件预测能力的自归一化检验AI 解读

This paper proposes self-normalized tests for multistep conditional predictive ability in forecast comparison. By normalizing the sample mean of the transformed loss differential using functionals of its cumulative sum (CUSUM) process, specifically an adjusted-range normalizer for scalars and a matrix normalizer for vectors, our approach avoids direct estimation of the long-run covariance matrix. Consequently, it eliminates the need for the ad hoc bandwidth, kernel, and…

CHASM：时间依赖与变量间依赖的在线变点检测AI 解读

Changepoint detection identifies times when the generative process of a time series changes, with applications in healthcare, cybersecurity, and finance. In multivariate settings, changes in cross-variable and temporal dependence are particularly challenging to detect, as they are often less pronounced than shifts in marginal statistics such as the mean or variance. Existing methods detect changes using reconstruction error, which provides only an indirect measure of…

基于证据先验的因果估计量贝叶斯敏感性分析AI 解读

Causal inference, especially in observational studies, relies on untestable assumptions about the true data-generating process. Sensitivity analysis helps us determine how robust our conclusions are when we alter these underlying assumptions. Existing frameworks for sensitivity analysis are concerned with worst-case changes in assumptions. In this work, we argue that using such pessimistic criteria can often become uninformative or lead to conclusions contradicting our prior…

结合秩统计量的个体处理效应分布随机化检验AI 解读

What proportion of treated units actually benefited from an experimental intervention? What is the median or the largest individual treatment effect? This paper develops methods for answering such questions about the distribution of individual causal effects in randomized experiments. Existing approaches require the analyst to select a rank-based test statistic before observing the data. A poor choice can substantially reduce power, while searching over multiple test…

“氛围计量经济学”与分析契约AI 解读

"Vibe coding" and "vibe analytics" have been framed as a democratization of technical capability. This paper argues that AI-assisted methodology more broadly, or what I call "vibe methodology," also democratizes the failure modes specific to each domain. When AI assists with methods whose validity depends on assumptions that cannot be verified from the output alone (a class I call "vibe inference"), the failure surface is structurally different: the output does not reliably…

局部平稳与弱依赖下的滚动起点保形预测AI 解读

We propose and analyse rolling-origin conformal prediction for time-series forecasting. The method calibrates the conformal quantile against the $m$ most recent pseudo-out-of-sample forecast errors, adapting to serial dependence, volatility clustering, and distributional drift that invalidate classical conformal guarantees. Under Hölder-$β$ local stationarity and $α$-mixing, we establish a four-term coverage-error decomposition and derive the optimal calibration window $m^{\star} \asymp T^{2β/(2β+1)}$…

Sinkhorn 处理效应：一种因果最优传输度量AI 解读

We introduce the Sinkhorn treatment effect, an entropic optimal transport measure of divergence between counterfactual distributions. Unlike classical quantities such as the average treatment effect, this measure captures differences across entire distributions. We analyze this divergence as a statistical functional and show it can be written as a smooth transformation of counterfactual mean embeddings with an appropriate kernel. This characterization allows us to establish…

非参数经验贝叶斯置信区间AI 解读

Empirical Bayes methods can improve inference on unobservable individual effects by borrowing strength across units. This paper proposes nonparametric empirical Bayes confidence intervals (NP-EBCIs) for unobservable individual effects in a normal means model. The oracle intervals are constructed from posterior quantiles under a point-identified, fully nonparametric prior; feasible intervals replace these quantiles with nonparametric estimates. The NP-EBCIs are asymptotically…

现代异质性稳健双重差分估计量的基于设计方差估计AI 解读

Modern heterogeneity-robust difference-in-differences estimators derive their asymptotic properties under iid, cluster, or fixed-design frameworks that abstract from complex survey sampling, yet practitioners routinely apply them to nationally representative surveys with stratified cluster designs. We show that, under standard regularity conditions, the influence functions of each smooth IF-based or regression-based modern DiD estimator satisfy Binder's (1983) smoothness…

启发式评分估计方法的适用充分条件AI 解读

A series of papers has introduced the Heuristic Rating Estimation method, which evaluates a set of alternatives based on pairwise comparisons and the weights of reference alternatives. We formulate the conditions under which the HRE method can be applied correctly. The research considers both arithmetic and geometric algorithms for complete and incomplete pairwise comparison methods. The illustrative examples show that the estimations of inconsistency in the arithmetic…

只拟合一次 CATE：无需样本分割的模型辅助随机化检验AI 解读

Randomization tests and flexible treatment-effect models offer complementary strengths for analyzing data from randomized panel experiments: the former provide valid inference under the known assignment mechanism, while the latter can capture complex patterns of effect heterogeneity. We develop model-assisted randomization tests that combine these strengths without sample splitting. The key idea is to estimate an unsigned version of the conditional average treatment effect…

可迁移分位数处理效应的嵌套敏感性包络AI 解读

We study target-population quantile treatment effects when a source study may have unmeasured treatment confounding and may not transport to a target population after conditioning on observed covariates. The observed data consist of a source sample with treatment, outcome and covariates, and a target sample with covariates only. We impose two marginal sensitivity restrictions: an odds-ratio bound \(\Gam\) for source treatment assignment and a conditional likelihood-ratio…