每日简报

生存分析中再随机化的渐近理论AI 解读

Rerandomization systematically reduces chance imbalance and can improve the efficiency of the average treatment effect estimator in randomized experiments. While the asymptotic properties of finite-dimensional M-estimators under rerandomization have been established, existing theory does not directly address survival outcomes under censoring, where the target estimand involves infinite-dimensional functional parameters. This article establishes the uniform weak convergence…

利用潜在高斯空间模型估计人为强迫对极端高温的因果归因AI 解读

Climate change has become a significant global concern due to its capacity to cause substantial disruption to daily life by increasing the frequency and intensity of extreme weather events. Given the rising trend of human interventions in the climate system over recent decades, this study aims to quantify the relative contribution of anthropogenic forcing to the increasing likelihood of climate extremes, with a particular emphasis on high-temperature extremes. Our analysis…

总体异质性下双样本孟德尔随机化的稳健框架AI 解读

Mendelian randomization is a powerful tool for causal inference in observational studies. The two-sample summary-data design, which estimates genetic associations with exposures and outcomes in separate cohorts, is the most widely used Mendelian randomization approach in large-scale genomic studies. However, this approach relies on a strong assumption of population homogeneity across the two samples. In practice, available samples often differ in ancestry, demographics,…

连续处理的多变量增量效应：环境混合暴露的健康影响AI 解读

Evaluating the causal health effects of multivariate, continuous exposures, such as air pollution mixtures, is a critical public health challenge. A primary obstacle is the frequent violation of the positivity assumption, which renders the effects of standard deterministic interventions unidentified or heavily reliant on unreliable model extrapolation. In this paper, we develop a novel causal inference framework to address this challenge. We extend exponential tilting to…

通过低秩基函数搜寻实现保护隐私的元分析AI 解读

A central challenge of meta-analysis is that the populations underlying existing studies often differ from the target population in unknown ways. We study the problem of predicting function-valued quantities, such as regression and conditional average treatment effect functions, for a new target population using only study-level covariates and study-specific function estimates. We propose MetaHunt, a new meta-analysis methodology based on a shared low-rank structure, in…

通过多重识别实现收缩估计AI 解读

We propose an empirical Bayes framework for combining estimators obtained from multiple identification functionals associated with the same estimand. We adaptively pool a collection of asymptotically linear estimators, each of which may target a different parameter because of violations of their identification assumptions. Although all estimators are computed from the same sample and are therefore dependent, we show that a working independence construction preserves…

混杂变量缺失下因果推断的双重稳健加权回归AI 解读

Missingness in confounders is common in observational studies and presents substantial challenges for causal effect estimation by weakening identification and increasing sensitivity to model misspecification. Within the missing-indicator framework, existing approaches typically rely on a single working model and achieve consistency only when that model is correctly specified and are therefore singly robust. In this article, we develop a doubly robust missing indicator…

贝叶斯变平面回归AI 解读

Change-plane regression represents treatment effect heterogeneity through an interpretable rule that assigns patients to two groups according to whether a linear score of baseline covariates crosses a threshold. Although easy to communicate, likelihood-based inference for the hard threshold is nonregular, invalidating standard large-sample approximations. We develop a Bayesian framework that replaces the sharp indicator with a smooth probit gate at a declared smoothing scale…

MOCA：采用单向交叉注意力与反馈切断的模块化因果推断框架AI 解读

Causal effect estimation from observational data requires careful adjustment for confounding. Classical estimators such as inverse probability weighting and augmented inverse probability weighting can perform well under favorable model specification but may become unstable in complex settings. Machine-learning and representation-learning methods provide greater flexibility, but joint optimization may allow outcome information to alter treatment representations and compromise…

主层可忽略性违反时主层因果效应的部分识别AI 解读

Principal stratification is a general framework for studying causal mechanisms involving post-treatment variables. When estimating principal causal effects, the principal ignorability assumption is commonly invoked, which we study in detail in this manuscript. Our first key contribution is studying a commonly used strategy of using parametric models to jointly model the outcome and principal strata without requiring the principal ignorability assumption. We show that even if…

基于加性树模型的两样本密度比比较AI 解读

The ratio of two densities provides a direct characterization of their differences. We consider the two-sample comparison problem by estimating this ratio given i.i.d. observations from two distributions. To this end, we propose additive tree models for density ratio estimation along with efficient algorithms using a new loss function, the balancing loss. The loss allows tree-based models to be trained using several algorithms originally designed for supervised learning,…

电子健康记录研究中随治疗启动时间变化的因果效应框架AI 解读

Standard practice in electronic health record (EHR)-based studies evaluating the comparative effectiveness of bariatric surgery relative to no surgery is to estimate and report a constant treatment effect across calendar time. However, real-world treatment strategies can evolve, particularly when comparators include standard of care or surgical procedures where techniques may improve, making it clinically important to ascertain whether efficacy of bariatric surgery has…

扰动效用随机交通均衡的敏感性分析AI 解读

This paper develops a sensitivity analysis framework for the perturbed utility route choice (PURC) model and the accompanying stochastic traffic equilibrium model. We derive analytical sensitivity expressions for the Jacobian of the individual optimal PURC flow and equilibrium link flows with respect to link cost parameters under general assumptions. This allows us to determine the marginal change in link flows following a marginal change in link costs across the network. We…

固定效应模型的刀切法推断AI 解读

This paper develops a general method of inference for fixed effects models which is (i) automatic, (ii) computationally inexpensive, (iii) tuning parameter-free, and (iv) highly model agnostic. Specifically, we show how to combine a collection of subsample estimators into a jackknife $t$-statistic, from which hypothesis tests, confidence intervals, and $p$-values are readily obtained.

重复匹配博弈的实证框架AI 解读

We introduce a model of dynamic matching with transferable utility, extending the static model of Shapley and Shubik (1971). Forward-looking agents have individual states that evolve with current matches. Each period, a matching market with market-clearing prices takes place. We prove the existence of an equilibrium with time-varying distributions of agent types and show it is the solution to a social planner's problem. We also prove that a stationary equilibrium exists. We…

balnet：协变量平衡倾向得分的路径估计AI 解读

We present balnet, an R package for scalable pathwise estimation of covariate balancing propensity scores via logistic covariate balancing loss functions. Regularization paths are computed with Yang and Hastie (2024)'s generic elastic net solver, supporting convex losses with non-smooth penalties, as well as group penalties and feature-specific penalty factors. For lasso penalization, balnet computes a regularization path of balancing weights from the largest observed…

反事实密度效应与德国东西部收入差距AI 解读

We propose a novel framework for conducting causal inference based on counterfactual densities. While the current paradigm of causal inference is mostly focused on estimating average treatment effects (ATEs), which restricts the analysis to the first moment of the outcome variable, our density-based approach is able to detect causal effects based on general distributional characteristics. Following the Oaxaca-Blinder decomposition approach, we consider two types of…

衡量健康不平等的因果方差分解AI 解读

Recent causal inference literature has introduced causal effect decompositions to quantify sources of observed inequalities or disparities in outcomes, but these approaches are typically limited to pairwise comparisons. In healthcare delivery settings, both the exposure of interest-hospital or healthcare unit-and sociodemographic group membership may be polytomous, making pairwise contrasts inadequate. We therefore take the observed variance in care delivery outcomes as the…

通过最优传输部分识别工具变量下的政策相关处理效应AI 解读

Policy-Relevant Treatment Effects (PRTEs) are generally not point-identified under standard Instrumental Variable (IV) assumptions when the instrument generates limited support in treatment propensity. We show that PRTE partial identification in the generalized Roy model can instead be formulated as a Constrained Conditional Optimal Transport (CCOT) problem over the joint conditional law of the potential outcome and the latent resistance. The resulting multidimensional CCOT…

基于设计的嵌套工具变量分析AI 解读

Two binary instrumental variables (IVs) are nested if individuals who comply under one binary IV also comply under the other. This situation often arises when the two IVs represent different intensities of encouragement or discouragement to take the treatment, with one stronger than the other. In a nested IV structure, treatment effects can be identified for two latent subgroups: always-compliers and switchers. Always-compliers are individuals who comply even under the…

考虑可允许性设定的因果分解分析估计策略AI 解读

Causal decomposition analysis (CDA) is an approach for modeling the impact of hypothetical interventions to reduce disparities. It is useful for identifying foci that future interventions, including multilevel and multimodal interventions, could focus on to reduce disparities. Based within the potential outcomes framework, CDA has a causal interpretation when the identifying assumptions are met. CDA also allows an analyst to consider which covariates are allowable (i.e.,…

回归调整的设计型有限样本分析AI 解读

In randomized experiments, regression adjustment can improve the precision of average treatment effect (ATE) estimation using covariates without requiring a correctly specified outcome model. Although well studied in low-dimensional settings, its behavior in high-dimensional regimes, where the number of covariates $p$ may exceed the number of observations $n$, remains underexplored. Moreover, existing analyses are largely asymptotic, providing limited guidance for…

因果元分析：重新审视循证医学的基础AI 解读

Meta-analysis, by synthesizing effect estimates from multiple studies conducted in diverse settings, stands at the top of the evidence hierarchy in clinical research. Yet, conventional approaches based on fixed- or random-effects models lack a causal framework, which may limit their interpretability and utility for public policy. Incorporating causal inference reframes meta-analysis as the estimation of well-defined causal effects on clearly specified populations, enabling a…

将行为实验发现融入动态模型以设计社会变革干预AI 解读

Addressing global challenges often involves stimulating the large-scale adoption of new products or behaviors. Research traditions that focus on individual decision making suggest that achieving this objective requires identifying the drivers of individual discrete adoption choices. On the other hand, computational approaches rooted in complexity science focus on maximizing the propagation of a given product or behavior throughout social networks of interconnected adopters.…