每日简报

随机对照试验中预后协变量调整的第一阶段估计不确定性AI 解读

Prognostic covariate adjustment (PROCOVA) is a two-sample two-stage estimation method for covariate adjustment in randomized controlled trials. In the first stage, a prognostic score, defined as the conditional expectation of an outcome given covariates under the control treatment, is estimated using historical data. In the second stage, analysis of covariance with the estimated prognostic score and treatment assignment as explanatory variables is performed, and the average…

不完整网络数据的灵活插补AI 解读

Sampled network data are widely used in empirical research because collecting complete network information is costly. However, empirical analyses based on sampled networks may lead to biased estimators. We propose a nonparametric imputation method for sampled networks and show that empirical analyses based on imputed networks yield consistent estimates. Our approach imputes missing network links by combining a projection onto covariates with a local two-way fixed-effects…

加权平均处理效应的一步目标最大似然估计AI 解读

We consider Targeted Maximum Likelihood Estimation (TMLE) of weighted average treatment effects (WATEs), a class of causal estimands that reweight the covariate distribution using a specified function of the propensity score. This class includes the average treatment effect and average treatment effect on the treated, as well as various overlap-based targets. We provide a comprehensive analysis of the one-step TMLE along the universal least favorable path for such…

含潜变量的多层断点回归模型AI 解读

Regression discontinuity (RD) analysis with latent variables as introduced by Morell et al. (2025), offers a useful augmentation of the conventional RD by incorporating measurement model. This approach is particularly relevant in education research, where noisy proxy (e.g., observed test score) of underlying latent construct is adopted for the running variable. This extension enables extrapolation of average treatment effect (ATE) away from the cutoff score and assessment of…

带固定效应的动态面板 Logit 模型识别AI 解读

We show that identification in a general class of dynamic panel logit models with fixed effects is related to the truncated moment problem from the mathematics literature. We use this connection to show that the identified set for structural parameters and functionals of the distribution of latent individual effects can be characterized by a finite set of conditional moment equalities subject to a certain set of shape constraints on the model parameters. In addition to…

从时间快照识别漂移、扩散与因果结构AI 解读

Stochastic differential equations (SDEs) are a fundamental tool for modelling dynamic processes, including gene regulatory networks (GRNs), contaminant transport, financial markets, and image generation. However, learning the underlying SDE from data is a challenging task, especially if individual trajectories are not observable. Motivated by burgeoning research in single-cell datasets, we present the first comprehensive approach for jointly identifying the drift and…

fixest：快速且功能丰富的 R 计量估计框架AI 解读

fixest is an R package for fast and flexible econometric estimation. It provides a unified framework for applied research, with comprehensive support for a diverse class of models: ordinary least squares, instrumental variables, generalized linear models, maximum likelihood, and difference-in-differences. The package particularly excels at fixed-effects estimation, supported by a novel fixed-point acceleration algorithm implemented in C++. This algorithm achieves rapid…

面向肥胖遗传变异的超高维数据知识整合分位数回归方法AI 解读

Obesity is widely recognized as a serious and pervasive health concern. We study obesity through body mass index (BMI), which is known to be highly heritable, and identify important genetic risk factors for BMI from hundreds of thousands of single nucleotide polymorphisms (SNPs) in the Framingham Study data. Several challenges arise when using traditional genome-wide association studies (GWAS): (1) They suffer from a low power due to a combination of a limited number of…

同时放宽单调性与独立性的工具变量敏感性分析AI 解读

In this paper I develop a breakdown frontier approach to assess the sensitivity of Local Average Treatment Effects (LATE) estimates to violations of monotonicity and independence of the instrument. I parametrize violations of independence using the concept of $c$-dependence from Masten & Poirier (2018) and allow for the share of defiers to be greater than zero but smaller than the share of compliers. I derive identified sets for the LATE and the Average Treatment Effect…

通过 Softmax 平滑推断最优政策价值及其他非正则泛函AI 解读

Constructing confidence intervals for the value of an (unknown) optimal treatment policy is a fundamental problem in causal inference. Insight into the optimal policy value can guide the development of reward-maximizing, individualized treatment regimes. However, because the functional that defines the optimal value is non-differentiable, standard semi-parametric approaches for performing inference fail to be directly applicable. Many existing works circumvent…

自适应实验的设计稳定性及其对处理效应估计的影响AI 解读

We study the problem of estimating the average treatment effect (ATE) under sequentially adaptive treatment assignment mechanisms. In contrast to classical completely randomized designs, we consider a setting in which the probability of assigning treatment to each experimental unit may depend on prior assignments and observed outcomes. Within the potential outcomes framework, we propose and analyze two natural estimators for the ATE: the inverse propensity weighted (IPW)…

因果推断中的外推正则化AI 解读

Many common estimators in machine learning and causal inference are linear smoothers, where the prediction is a weighted average of the training outcomes. Some estimators, such as ordinary least squares and kernel ridge regression, allow for arbitrarily negative weights, which improve feature imbalance but often at the cost of increased dependence on parametric modeling assumptions and higher variance. By contrast, estimators like importance weighting and random forests…

通过广义贝叶斯对参数模型进行自适应非参数扰动AI 解读

Parametric Bayesian modeling offers a powerful and flexible toolbox for machine learning. Yet the model, however detailed, may still be wrong, and this can make inferences untrustworthy. In this paper we introduce a new class of semiparametric corrections for parametric Bayesian models, when the target of inference is a functional of the true data distribution. Our starting point is a fully Bayesian modeling approach, which explicitly accounts for the possibility that the…

Causal-DRF：基于分布随机森林的条件核处理效应估计AI 解读

The conditional average treatment effect (CATE) is a commonly targeted statistical parameter for measuring the effect of a treatment conditional on covariates. However, the CATE will fail to capture effects of treatments beyond differences in conditional expectations. Inspired by causal forests for CATE estimation, we develop a forest-based method to estimate the conditional kernel treatment effect (CKTE), based on the recently introduced Distributional Random Forest (DRF)…

Causal-ICM：用多任务高斯过程融合数据估计异质处理效应AI 解读

Bridging the gap between internal and external validity is crucial for heterogeneous treatment effect estimation. Randomised controlled trials (RCTs), favoured for their internal validity due to randomisation, often encounter challenges in generalising findings due to strict eligibility criteria. Observational studies, on the other hand, may provide stronger external validity through larger and more representative samples but can suffer from compromised internal validity due…

因果 K 均值聚类AI 解读

Causal effects are often characterized with population summaries. These might provide an incomplete picture when there are heterogeneous treatment effects across subgroups. Since the subgroup structure is typically unknown, it is more challenging to identify and evaluate subgroup effects than population effects. We propose a new solution to this problem: \emph{Causal k-Means Clustering}, which leverages the k-means clustering algorithm to uncover the unknown subgroup…

局部平均处理效应框架下聚类数据的两阶段最小二乘AI 解读

To estimate the causal effect of an endogenous treatment using clustered data, the canonical two-stage least squares (2sls) estimates a linear regression of the outcome on treatment status using an instrumental variable (IV) and conducts inference with cluster-robust standard errors. When both the treatment and the IV vary within clusters, an alternative two-stage least squares with fixed effects (2sfe) additionally includes cluster indicators in the regression, thereby…

非精确匹配观察研究中平均处理效应的随机化推断AI 解读

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated units are exactly matched with controls on these covariates, enabling randomization-based inference for treatment effects as in a randomized experiment, under the assumption of no unobserved covariates. However, inexact matching often occurs,…

内生性与异方差下删失分位数回归的分布效应AI 解读

Distributional effects, captured by quantile frameworks, are well-received for characterizing heterogeneous impacts of economic factors across the unobserved relative ranks. Censored outcome, endogenous regressor and heteroskedastic error are prevalent in empirical work, yet challenge the consistency of existing quantile estimation methods. This paper proposes a two-nested-step(TNS) estimation method for distributional effects in censored quantile models with endogeneity and…

结果分布偏移下处理效应推广的锐界AI 解读

Generalizing treatment effects from a randomized trial to a target population requires the assumption that potential outcome distributions are invariant across populations after conditioning on observed covariates. This assumption fails when unmeasured effect modifiers are distributed differently between trial participants and the target population. We develop a sensitivity analysis framework that bounds how much conclusions can change when this transportability assumption…

未知因果图上的因果老虎机：结合后门调整的置信上界AI 解读

The causal bandit problem seeks to identify, through sequential experimentation, an intervention that maximizes the expected reward in a causal system modeled by a directed acyclic graph (DAG). Existing methods typically assume that the causal graph is known or impose restrictive structural assumptions. In this paper, we study causal bandit problems when the causal graph is unknown. We first consider Gaussian DAG models without latent confounders. By combining observational…

随机对照试验中存在竞争性伴发事件的处理效应估计AI 解读

The analysis of randomized controlled trials is often complicated by intercurrent events (IEs) -- events that occur after treatment initiation and affect either the interpretation or existence of outcome measurements. Examples include treatment discontinuation or the use of additional medications. In two recent clinical trials for systemic lupus erythematosus with complications of IEs, we classify the IEs into two broad categories: effect-informative (e.g., treatment…

通过基于模拟的推断改进因果评估的生成方法AI 解读

Generating synthetic datasets that accurately reflect real-world observational data is critical for evaluating causal estimators, but it remains a challenging task. Existing generative methods offer a solution by producing synthetic datasets anchored in the observed data (source data) while allowing variation in key parameters such as the treatment effect and amount of confounding bias. However, it is often unclear which generative methods to use and which values of…

因果空间中因果效应的细粒度分析AI 解读

The notion of causal effect is fundamental across many scientific disciplines. Traditionally, quantitative researchers have studied causal effects at the level of variables; for example, how a certain drug dose (W) causally affects a patient's blood pressure (Y). However, in many modern data domains, the raw variables-such as pixels in an image or tokens in a language model-do not have the semantic structure needed to formulate meaningful causal questions. In this paper, we…