每日简报

通过双重阈值实现稀疏组主成分分析：多细胞程序应用AI 解读

Multi-cellular programs (MCPs) are coordinated patterns of gene expression across interacting cell types that collectively drive complex biological processes such as tissue development and immune responses. While MCPs are typically estimated from high-dimensional gene expression data using methods like sparse principal component analysis or latent factor models, these approaches often suffer from high computational costs and limited statistical power. In this work, we…

在真实实验中将因果消息传递与网络感知方法比较验证AI 解读

Estimating total treatment effects in the presence of network interference typically requires knowledge of the underlying interaction structure. However, in many practical settings, network data is either unavailable, incomplete, or measured with substantial error. We demonstrate that causal message passing, a methodology that leverages temporal structure in outcome data rather than network topology, can recover total treatment effects comparable to network-aware approaches.…

通过最小有效分段实现精确多变点检测AI 解读

We introduce smallest valid partitioning (SVP), a segmentation method for multiple change-point detection in time-series. SVP relies on a local notion of segment validity: a candidate segment is retained only if it passes a user-chosen validity test (e.g., a single change-point test). From the collection of valid segments, we propose a coherent aggregation procedure that constructs a global segmentation which is the exact solution of an optimization problem. Our main…

双重变量重要性匹配：区分事件概率与发生时间的因果效应AI 解读

In many clinical contexts, estimating effects of treatment in time-to-event data is complicated not only by confounding, censoring, and heterogeneity, but also by the presence of a cured subpopulation in which the event of interest never occurs. In such settings, treatment may have distinct effects on (1) the probability of being cured and (2) the event timing among non-cured individuals. Standard survival analysis and causal inference methods typically do not separate cured…

通过离散实验学习个性化连续策略：理论与实证证据AI 解读

Randomized Controlled Trials (RCTs), or A/B testing, have become the gold standard for optimizing various operational policies on online platforms. However, RCTs on these platforms typically cover a limited number of discrete treatment levels, while the platforms increasingly face complex operational challenges involving optimizing continuous variables, such as pricing and incentive programs. The current industry practice involves discretizing these continuous decision…

间歇参与下的预测综合：来自通胀密度调查的证据AI 解读

Central banks rely on density forecasts from professional surveys to assess inflation risks and communicate uncertainty. A central challenge in using these surveys is irregular participation: forecasters enter and exit, skip rounds, and reappear after long gaps. In the European Central Bank's Survey of Professional Forecasters, turnover and missingness vary substantially over time, causing the set of submitted predictions to change from quarter to quarter. Standard…

双线性形式检验的不变性修正AI 解读

The invariance properties of certain likelihood-based asymptotic tests as well as their extensions for M-estimation, estimating functions and the generalized method of moments have been well studied. The simulation study reported in Crudu and Osorio [Econ. Lett. 187: 108885, 2020] shows that the bilinear form test is not invariant to one-to-one transformations of the parameter space. This paper provides a set of suitable conditions to establish the invariance property under…

在线广告中停止随机游走的因果推断AI 解读

We consider a causal inference problem frequently encountered in online advertising systems, where a publisher (e.g., Instagram, TikTok) interacts repeatedly with human users and advertisers by sporadically displaying to each user an advertisement selected through an auction. Each treatment corresponds to a parameter value of the advertising mechanism (e.g., auction reserve-price), and we want to estimate through experiments the corresponding long-term treatment effect…

条件异方差时间序列模型的稳健贝叶斯估计AI 解读

Outliers can seriously distort statistical inference by inducing excessive sensitivity in the likelihood function, thereby compromising the reliability of Bayesian estimation. To address this issue, we develop a robust Bayesian estimation method for conditionally heteroscedastic time series models by extending the density power divergence (DPD) framework to the Bayesian setting. The resulting DPD-based posterior distribution, controlled by a tuning parameter, achieves a…

基于高频数据的积分扩散过程预测型推断AI 解读

We consider parametric inference for an ergodic and stationary diffusion process, when the data are high-frequency observations of the integral of the diffusion process. Such data are obtained via certain measurement devices, or if positions are recorded and speed is modelled by a diffusion. In finance, realized volatility or variations thereof can be used to construct observations of the latent integrated volatility process. Specifically, we assume that the integrated…

具有非参数不可观测异质性的网络模型识别与估计AI 解读

Homophily based on observables is widespread in networks. Therefore, homophily based on unobservables (fixed effects) is also likely to be an important determinant of the interaction outcomes. Failing to properly account for latent homophily (and other complex forms of unobserved heterogeneity) can result in inconsistent estimators and misleading policy implications. To address this concern, we consider a network model with nonparametric unobserved heterogeneity, leaving the…

差异化产品需求的嵌套伪 GMM 估计AI 解读

We propose a fast algorithm for computing the GMM estimator in the BLP demand model (Berry, Levinsohn, and Pakes, 1995). Inspired by nested pseudo-likelihood methods for dynamic discrete choice models, our approach avoids repeatedly solving the inverse demand system by swapping the order of the GMM optimization and the fixed-point computation. We show that, by fixing consumer-level outside-option probabilities, BLP's market-share to mean-utility inversion becomes closed-form…

穷尽子组处理效应图中反对同质性的证据评估AI 解读

Exhaustive subgroup treatment effect plots are constructed by displaying all subgroup treatment effects of interest against subgroup sample size, providing a useful overview of the observed treatment effect heterogeneity in a clinical trial. As in any exploratory subgroup analysis, however, the observed estimates suffer from small sample sizes and multiplicity issues. To facilitate more interpretable exploratory assessments, this paper introduces a computationally efficient…

一阶退化下的统计推断AI 解读

We study inference in models where a transformation of parameters exhibits first-order degeneracy -- that is, its gradient is zero or close to zero, making the standard delta method invalid. A leading example is causal mediation analysis, where the indirect effect is a product of coefficients and the gradient degenerates near the origin. In these local regions of degeneracy the limiting behaviors of plug-in estimators depend on nuisance parameters that are not consistently…

圆形散光生物标志物治疗效应的双曲几何统计推断AI 解读

Circular biomarkers arise naturally in many biomedical applications, particularly in ophthalmology, where angular measurements such as astigmatism are routinely recorded. Similar directional variables also occur in the study of human body rotations, including movements of the hand, waist, neck, and lower limbs. Motivated by a clinical dataset comprising angular measurements of astigmatism induced by two cataract surgery procedures, we propose a novel two-sample testing…

ODDM 系统中基于分层稀疏贝叶斯学习的信道估计AI 解读

Orthogonal delay-Doppler division multiplexing (ODDM) is a promising modulation technique for reliable communications in high-mobility scenarios. However, the existing channel estimation frameworks for ODDM systems cannot achieve both high accuracy and low complexity simultaneously, due to the inherent coupling of delay and Doppler parameters. To address this problem, a two-dimensional (2D) hierarchical sparse Bayesian learning (HSBL) based channel estimation framework is…

非平衡两层与三层模型中中心矩的无偏估计AI 解读

This paper derives closed-form unbiased estimators of central moments in multilevel random-effects models with unbalanced group sizes. In a two-level model, we provide unbiased estimators for the second, third, and fourth central moments under both group-level and observation-level averaging. In a three-level model, we provide unbiased estimators for the second and third central moments.

收益预测样本外 R² 的非平凡上界AI 解读

This study establishes a nontrivial upper bound on the out-of-sample $R^2$ ($R^2_{\text{OOS}}$) in return forecasting. In particular, we define a coin-flip oracle model that, under the same directional accuracy, theoretically outperforms practical models in terms of MSE. The $R^2_{\text{OOS}}$ of the oracle model, whose analytical expression is a quadratic function of directional accuracy, can therefore serve as a tractable upper bound on the actual $R^2_{\text{OOS}}$.…

考虑可允许性设定的因果分解分析估计策略AI 解读

Causal decomposition analysis (CDA) is an approach for modeling the impact of hypothetical interventions to reduce disparities. It is useful for identifying foci that future interventions, including multilevel and multimodal interventions, could focus on to reduce disparities. Based within the potential outcomes framework, CDA has a causal interpretation when the identifying assumptions are met. CDA also allows an analyst to consider which covariates are allowable (i.e.,…

CausalCompass：模型错设情景下时间序列因果发现的稳健性评估AI 解读

Causal discovery from time series is a fundamental task in machine learning. However, its widespread adoption is hindered by a reliance on untestable causal assumptions and by the lack of robustness-oriented evaluation in existing benchmarks. To address these challenges, we propose CausalCompass, a flexible and extensible benchmark framework designed to assess the robustness of time-series causal discovery (TSCD) methods under violations of modeling assumptions. To…

调查实验中的协变量平衡AI 解读

The survey experiment is widely used in economics and social sciences to evaluate the effects of treatments or programs. In a standard population-based survey experiment, the experimenter randomly draws experimental units from a target population of interest and then randomly assigns the sampled units to treatment or control conditions to explore the treatment effect of an intervention. Simple random sampling and treatment assignment can balance covariates on average.…

SC3D：时序与即时因果图的动态可微发现AI 解读

Discovering causal structures from multivariate time series is a key problem because interactions span across multiple lags and possibly involve instantaneous dependencies. Additionally, the search space of the dynamic graphs is combinatorial in nature. In this study, we propose Stable Causal Dynamic Differentiable Discovery (SC3D), a two-stage differentiable framework that jointly learns lag-specific adjacency matrices and, if present, an instantaneous directed acyclic…

Medicare 医保支付中事件报告不可靠时的生存时间估计AI 解读

OBJECTIVE: To propose time-to-event estimators that help evaluate incident diagnostic coding and possible upcoding in Medicare as well as introduce an open-source software package that enables more reproducible methods development relevant to Medicare billing behavior. STUDY SETTING AND DESIGN: Observational analysis of simulated upcoding based on coding by insurers or providers that may be incentivized by Medicare Advantage risk adjustment. DATA SOURCES AND ANALYTIC SAMPLE:…

不完备物理模型下异方差随机动力系统的因果发现AI 解读

Causal discovery is a data-driven paradigm for analyzing complex systems, while physics-based models, such as ordinary differential equations (ODEs), provide mechanistic structure for real-world dynamical processes. Integrating these paradigms can improve identifiability, stability, and robustness. However, real dynamical systems often exhibit cyclic interactions and nonstationarity, whereas many causal discovery methods rely on acyclicity, stationarity, or equilibrium…