每日简报

全体处理相对全体不处理的平均效应线性估计AI 解读

We study estimation of and inference for the average causal effect of treating every member of a population, as opposed to none, using an experiment that treats only some. Considering settings where spillovers can occur between any pair of units and decay slowly with distance, we derive the minimax rate over all linear estimators and experimental designs, which increases with the spatial rate of spillover decay. This rate of convergence can be achieved using an inverse…

迈向可识别的潜在加性噪声模型AI 解读

Causal representation learning (CRL) offers the promise of uncovering the underlying causal model by which observed data was generated, but the practical applicability of existing methods remains limited by the strong assumptions required for identifiability and by challenges in applying them to real-world settings. Most current approaches are applicable only to relatively restrictive model classes, such as linear or polynomial models, which limits their flexibility and…

协作图套索的多组学网络重建AI 解读

Motivation: In recent years, the availability of multi-omics data has increased substantially. Multi-omics data integration methods mainly aim to leverage different molecular layers to gain a complete molecular description of biological processes. An attractive integration approach is the reconstruction of multi-omics networks. However, the development of effective multi-omics network reconstruction strategies lags behind. Results: In this study, we introduce collaborative…

多维异质性动态非线性面板的去偏推断AI 解读

We introduce a generic class of dynamic nonlinear heterogeneous parameter models that incorporate individual and time fixed effects in both the intercept and slope. These models are subject to the incidental parameter problem, in that the limiting distribution of the point estimator is not centered at zero, and that test statistics do not follow their standard asymptotic distributions as in the absence of the fixed effects. To address the problem, we develop an analytical…

允许弃权的政策学习AI 解读

Policy learning algorithms are widely used in areas such as personalized medicine and advertising to develop individualized treatment regimes. However, most methods force a decision even when predictions are uncertain, which is risky in high-stakes settings. We study policy learning with abstention, where a policy may defer to a safe default or an expert. When a policy abstains, it receives a small additive reward on top of the value of a random guess. We propose a two-stage…

ScoreMatchingRiesz：用于去偏机器学习与政策路径估计的得分匹配AI 解读

We propose ScoreMatchingRiesz, a family of Riesz representer estimators based on score matching. The Riesz representer is a key nuisance component in debiased machine learning, enabling $\sqrt{n}$-consistent and asymptotically efficient estimation of causal and structural targets via Neyman-orthogonal scores. We formulate Riesz representer estimation as a score estimation problem. This perspective stabilizes representer estimation by allowing us to leverage denoising score…

集群随机交叉试验中存活者平均因果效应的贝叶斯方法AI 解读

In cluster-randomized crossover (CRXO) trials, groups of individuals are randomly assigned to two or more sequences of alternating treatments. Since clusters serve as their own control, the CRXO design is typically more statistically efficient than the usual parallel-arm design. CRXO trials are increasingly popular in many areas of health research where the number of available clusters is limited. Further, in trials among severely ill patients, researchers often want to…

分期推广集群随机实验中动态因果效应的模型辅助推断AI 解读

Staggered rollout cluster randomized experiments (SR-CREs) involve sequential treatment adoption across clusters, requiring analysis methods that address a general class of dynamic causal effects, anticipation, and non-ignorable cluster-period sizes. Without imposing any outcome modeling assumptions, we study regression estimators using individual data, cluster-period averages, and scaled cluster-period totals, with and without covariate adjustment from a design-based…

临床试验中的数据驱动子群选择与错误率控制AI 解读

Subgroup selection in clinical trials is essential for identifying patient groups that react differently to a treatment, thereby enabling personalised medicine. In particular, subgroup selection can identify patient groups that respond particularly well to a treatment or that encounter adverse events more often. However, this is a post-selection inference problem, which may pose challenges for traditional techniques used for subgroup analysis, such as increased Type I error…

估计异质性处理效应的混合元学习器AI 解读

Estimating conditional average treatment effects (CATE) from observational data involves modeling decisions that differ from supervised learning, particularly concerning how to regularize model complexity. Previous approaches can be grouped into two primary "meta-learner" paradigms that impose distinct inductive biases. Indirect meta-learners first fit and regularize separate potential outcome (PO) models and then estimate CATE by taking their difference, whereas direct…

合成回归控制法AI 解读

Estimating weights in the synthetic control method, typically resulting in sparse weights where only a few control units have non-zero weights, involves an optimization procedure that selects and combines control units to closely match the treated unit. However, it is not uncommon for the linear combination of pre-treatment period outcomes for the control units, using nonnegative weights with the constraint that their sum equals one, to inadequately approximate the…

连续暴露的增量效应AI 解读

Causal inference problems often involve continuous treatments, such as dose, duration, or frequency. However, identifying and estimating standard dose-response estimands requires that everyone has some chance of receiving any level of the exposure (i.e., positivity). To avoid this assumption, we consider stochastic interventions based on exponentially tilting the treatment distribution by some parameter $δ$ (an incremental effect); this increases or decreases the likelihood…

用预后评分调整提升广义线性模型随机试验边际效应分析的功效AI 解读

In randomized clinical trials (RCTs), the accurate estimation of marginal treatment effects is crucial for determining the efficacy of interventions. Enhancing the statistical power of these analyses is a key objective for statisticians. The increasing availability of historical data from registries, prior trials, and health records presents an opportunity to improve trial efficiency. However, many methods for historical borrowing compromise strict type-I error rate control.…

策略行为主体的信息排序检验AI 解读

Specifying the information structure in strategic environments is difficult for empirical researchers. We develop a test of information ordering that examines whether the true information structure is at least as informative as a proposed baseline. Using Bayes Correlated Equilibrium (BCE), we translate the ordering of information structures into testable moment inequalities and establish uniform asymptotic validity for our testing procedure. In an application to U.S. airline…

存在不依从的两阶段处理：用多地点工具变量识别累积平均效应AI 解读

When evaluating a two-phase intervention, the cumulative average treatment effect (ATE) is often the primary causal estimand of interest. However, some individuals who do not respond well to the Phase I treatment may subsequently display noncompliant behaviors. At the same time, exposure to the Phase I treatment is expected to directly influence an individual's potential outcomes, thereby violating the exclusion restriction. Building on an instrumental variable (IV) strategy…

平均处理效应估计中偏差校正项的直接估计AI 解读

This study considers the estimation of the direct bias-correction term for estimating the average treatment effect (ATE). Let $\{(X_i, D_i, Y_i)\}_{i=1}^{n}$ be the observations, where $X_i$ denotes $K$-dimensional covariates, $D_i \in \{0, 1\}$ denotes a binary treatment assignment indicator, and $Y_i$ denotes an outcome. In ATE estimation, $h_0(D_i, X_i) = \frac{1[D_i = 1]}{e_0(X_i)} - \frac{1[D_i = 0]}{1 - e_0(X_i)}$ is called the bias-correction term, where $e_0(X_i)$ is…