每日简报

外部验证研究中回归校准测量误差校正的可迁移性AI 解读

In nutritional and environmental epidemiology, exposures are impractical to measure accurately, while practical measures for these exposures are often subject to substantial measurement error. Regression calibration is among the most used measurement error correction methods with external validation studies. The use of external studies to assess the measurement error process always carries the risk of introducing estimation bias into the main study analysis. Although the…

重叠加权是什么、如何发展及何时用于因果推断AI 解读

The growing availability of large health databases has expanded the use of observational studies for comparative effectiveness research. Unlike randomized trials, observational studies must adjust for systematic differences in patient characteristics between treatment groups. Propensity score methods, including matching, weighting, stratification, and regression adjustment, address this issue by creating groups that are comparable with respect to measured covariates. Among…

个体与整群随机试验中治疗占优限制平均时间的双重稳健估计AI 解读

Progressive multi-state survival outcomes are common in trials with recurrent or sequential events and require treatment effect estimands that remain interpretable without proportional intensity or Markov assumptions. The restricted mean time in favor of treatment (RMT-IF) extends the restricted mean survival time to ordered multi-state processes and provides such an interpretable estimand. However, existing RMT-IF methods are nonparametric, assume covariate-independent…

异质性处理效应工具变量模型的可证伪性AI 解读

In this paper I derive a set of testable implications for econometric models defined by three assumptions: (i) the existence of strictly exogenous discrete instruments, (ii) restrictions on how the instruments affect adoption of a finite number of treatment types (such as monotonicity), and (iii) the assumption that the instruments only affect outcomes through their effect on treatment adoption (i.e. an exclusion restriction). The testable implications aggregate (via…

稳健 X-Learner：用稳健交叉插补应对不平衡与厚尾AI 解读

Estimating Heterogeneous Treatment Effects (HTE) in industrial applications such as AdTech and healthcare presents a dual challenge: extreme class imbalance and heavy-tailed outcome distributions. While the X-Learner framework effectively addresses imbalance through cross-imputation, we demonstrate that it is fundamentally vulnerable to "Outlier Smearing" when reliant on Mean Squared Error (MSE) minimization. In this failure mode, the bias from a few extreme observations…

多结局整群随机试验中广义因果效应的最优估计AI 解读

Cluster-randomized trials (CRTs) are widely used to evaluate group-level interventions and increasingly collect multiple outcomes capturing complementary dimensions of benefit and risk. Investigators often seek a single global summary of treatment effect, yet existing methods largely focus on single-outcome estimands or rely on model-based procedures with unclear causal interpretation or limited robustness. We develop a unified potential outcomes framework for generalized…

三者成群：存在溢出效应时三重差分模型的识别挑战AI 解读

The paper studies identification in triple-difference designs when spillover effects contaminate one or more control groups. We show that, under conventional identifying assumptions, the triple-difference model fails to identify both the treatment effect and the spillover effect under such interference. To overcome this limitation, we propose an alternative specification, the double-triple-difference model, and explicitly formalize identifying assumptions and spillover…

通过因子暴露映射对高维营养数据开展贝叶斯非参数因果推断AI 解读

Diet plays a crucial role in health, and understanding the causal effects of dietary patterns is essential for informing public health policy and personalized nutrition strategies. However, causal inference in nutritional epidemiology faces several challenges: (i) high-dimensional and correlated food/nutrient intake data induce massive treatment levels; (ii) nutritional studies are interested in latent dietary patterns rather than single food items; and (iii) the goal is to…

不完全依从下析因设计与面板实验的有限总体推断AI 解读

This paper develops a finite population framework for analyzing causal effects in settings with imperfect compliance where multiple treatments affect the outcome of interest. Two prominent examples are factorial designs and panel experiments with imperfect compliance. I define finite population causal effects that capture the relative effectiveness of alternative treatment sequences. I provide nonparametric estimators for a rich class of factorial and dynamic causal effects…

通过 Wasserstein 生成对抗网络恢复反事实分布AI 解读

Standard Distributional Synthetic Controls (DSC) estimate counterfactual distributions by minimizing the Euclidean $L_2$ distance between quantile functions. We demonstrate that this geometric reliance renders estimators fragile: they lack informative gradients under support mismatch and produce structural artifacts when outcomes are multimodal. This paper proposes a robust estimator grounded in Optimal Transport (OT). We construct the synthetic control by minimizing the…

统计决策与部分识别：边界不连续设计的应用AI 解读

We are delighted to respond to the excellent surveys by Cattaneo et al. (2026) and Hirano (2026). Our discussion will attempt two things: first, we show how statistical decision theory can be applied to situations with partial identification; second, we connect the surveys' themes by applying these insights to an imagined policy experiment in one of Cattaneo et al.'s (2025) applications. To do so, we lay out a stylized scenario of statistical decision making under partial…

近端替代指标：未观测混杂下的长期处理效应AI 解读

We study the identification and estimation of long-term treatment effects under unobserved confounding by combining an experimental sample, where the long-term outcome is missing, with an observational sample, where the treatment assignment is unobserved. While standard surrogate index methods fail when unobserved confounders exist, we establish novel identification results by leveraging proxy variables for the unobserved confounders. We further develop multiply robust…

增量干预效应的敏感性分析：受害经历与违法行为研究AI 解读

Sensitivity analysis for unmeasured confounding under incremental propensity score interventions remains relatively underdeveloped. Incremental interventions define stochastic treatment regimes by multiplying the odds of treatment, offering a flexible framework for causal effect estimation. To study incremental effects when there are unobserved confounders, we adopt Rosenbaum's sensitivity model in single time point settings, and propose a doubly robust estimator for the…

因果推断中的分布平衡：基于特征函数距离的统一框架AI 解读

Weighting methods are essential tools for estimating causal effects in observational studies, with the goal of balancing pre-treatment covariates across treatment groups. Traditional approaches pursue this objective indirectly, for example, via inverse propensity score weighting or by matching a finite number of covariate moments, and therefore do not guarantee balance of the full joint covariate distributions. Recently, distributional balancing methods have emerged as…

分布型工具变量：识别与分位数最小二乘估计AI 解读

We study instrumental-variable designs where policy reforms strongly shift the distribution of an endogenous variable but only weakly move its mean. We formalize this by introducing distributional relevance: instruments may be purely distributional. Within a triangular model, distributional relevance suffices for nonparametric identification of average structural effects via a control function. We then propose Quantile Least Squares (Q-LS), which aggregates conditional…

未测混杂下的信息论因果界AI 解读

We develop a data-driven information-theoretic framework for sharp partial identification of causal effects under unmeasured confounding. Existing approaches often rely on restrictive assumptions, such as bounded or discrete outcomes; require external inputs (for example, instrumental variables, proxies, or user-specified sensitivity parameters); necessitate full structural causal model specifications; or focus solely on population-level averages while neglecting…

干扰、同质性与稳健性权衡下的最优实验设计AI 解读

To minimize the mean squared error (MSE) in global average treatment effect (GATE) estimation under network interference, a popular approach is to use a cluster-randomized design. However, in the presence of homophily, which is common in social networks, cluster randomization can instead increase the MSE. We develop a novel potential outcomes model that accounts for interference, homophily, and heterogeneous variation. In this setting, we establish a framework for optimizing…

局部平均处理效应框架下聚类数据的两阶段最小二乘AI 解读

To estimate the causal effect of an endogenous treatment using clustered data, the canonical two-stage least squares (2sls) estimates a linear regression of the outcome on treatment status using an instrumental variable (IV) and conducts inference with cluster-robust standard errors. When both the treatment and the IV vary within clusters, an alternative two-stage least squares with fixed effects (2sfe) additionally includes cluster indicators in the regression, thereby…

倾向得分传播：未知倾向得分下基于设计的推断框架AI 解读

Design-based inference, also known as randomization-based or finite-population inference, provides a principled framework for trustworthy statistical inference. It attributes randomness solely to the design mechanism, such as treatment assignment, survey sampling, or missingness, without imposing super-population distributional or modeling assumptions on the outcome data. From the seminal work of Fisher and Neyman to its recent resurgence, design-based inference has played a…

未观测混杂下二元结果的双向因果推断AI 解读

Bidirectional causal relationships arising from mutual interactions between variables are commonly observed within biomedical, econometrical, and social science contexts. When such relationships are further complicated by unobserved factors, identifying causal effects in both directions becomes especially challenging. For continuous variables, methods that utilize two instrumental variables from both directions have been proposed to explore bidirectional causal effects…

Governments and development partners often seek Sustainable Development Goal (SDG) "accelerators" whose progress can propagate gains across human well-being, institutions, resources, and environmental priorities. Such claims require evidence on direction, timing, robustness, and trade-offs, not only network connectivity. We map directed SDG interdependence using a balanced panel of 114 countries observed annually from 2000 to 2024. Because the goal series are persistent,…

价格实验与干扰AI 解读

In this paper, we examine the biases that arise when firms run A/B tests on continuous parameters to estimate global treatment effects on performance metrics of interest; we particularly focus on price experiments to measure the price impact on quantity demanded, and on profit. In canonical A/B experimental estimators, biases emerge due to interference between market participants. We employ structural modeling and differential calculus to derive intuitive characterizations…

dynamite：用于动态多变量面板模型的 R 包AI 解读

dynamite is an R package for Bayesian inference of intensive panel (time series) data comprising multiple measurements per multiple individuals measured in time. The package supports joint modeling of multiple response variables, time-varying and time-invariant effects, a wide range of discrete and continuous distributions, group-specific random effects, latent factors, and customization of prior distributions of the model parameters. Models in the package are defined via a…

离散变动下多处理模型的识别AI 解读

We develop a marginal treatment effect based method to learn about causal effects in multiple treatment models with discrete instruments. We allow selection into treatment to be governed by a general class of threshold crossing models that permit multidimensional unobserved heterogeneity. An inherent complication is that the primitives characterizing the selection model are not generally point-identified. Allowing these primitives to be point-identified up to a…