每日简报

比较配对事件时间的效应度量AI 解读

The progression-free survival ratio (PFSr) is a widely used measure in personalized oncology trials. It evaluates the effectiveness of treatment by comparing two consecutive event times - one under standard therapy and one under an experimental treatment. However, most proposed tests based on the PFSr cannot control the nominal type I error rate, even under mild assumptions such as random right-censoring. Consequently the results of these tests are often unreliable. As a…

汇总因果图中微观因果效应的有效协变量调整AI 解读

Observational studies in fields such as epidemiology often rely on covariate adjustment to estimate causal effects. Classical graphical criteria, like the back-door criterion and the generalized adjustment criterion, are powerful tools for identifying valid adjustment sets in directed acyclic graphs (DAGs). However, these criteria are not directly applicable to summary causal graphs (SCGs), which are abstractions of DAGs commonly used in dynamic systems. In SCGs, each node…

一般线性泛函估计的尖锐结构无关下界AI 解读

We establish a general statistical optimality theory for estimation problems where the target parameter is a linear functional of an unknown nuisance component that must be estimated from data. This formulation covers many causal and predictive parameters and has applications to numerous disciplines. We adopt the structure-agnostic framework introduced by \citet{balakrishnan2023fundamental}, which poses no structural properties on the nuisance functions other than access to…

时间序列事件巧合检测中的假阳性控制AI 解读

We study the problem of coincidence detection in time series data, where we aim to determine whether the appearance of simultaneous or near-simultaneous events in two time series is indicative of some shared underlying signal or synchronicity, or might simply be due to random chance. This problem arises across many applications, such as astrophysics (e.g., detecting astrophysical events such as gravitational waves, with two or more detectors) and neuroscience (e.g.,…

从多模型到一个预测：基于储备池集成的宏观预测AI 解读

Model combination is a powerful approach for achieving superior performance compared to selecting a single model. We study both theoretically and empirically the effectiveness of ensembles of Multi-Frequency Echo State Networks (MFESNs), which have been shown to achieve state-of-the-art macroeconomic time series forecasting results (Ballarin et al., 2024a). The Hedge and Follow-the-Leader schemes are discussed, and their online learning guarantees are extended to settings…

临床试验中的数据驱动子群选择与错误率控制AI 解读

Subgroup selection in clinical trials is essential for identifying patient groups that react differently to a treatment, thereby enabling personalised medicine. In particular, subgroup selection can identify patient groups that respond particularly well to a treatment or that encounter adverse events more often. However, this is a post-selection inference problem, which may pose challenges for traditional techniques used for subgroup analysis, such as increased Type I error…

秩相关系数的渐近推断AI 解读

Kendall's tau and Spearman's rho are widely used tools for measuring dependence. Surprisingly, when it comes to asymptotic inference for these rank correlations, some fundamental results and methods have not yet been developed, in particular for discrete random variables and in the time series case, and concerning variance estimation in general. Consequently, asymptotic confidence intervals are not available. We provide a comprehensive treatment of asymptotic inference for…

随机对照试验分析中的贝叶斯可能响应者方法AI 解读

An important goal of precision medicine is to personalize medical treatment by identifying individuals who are most likely to benefit from a specific treatment. The Likely Responder (LR) framework, which identifies a subpopulation where treatment response is expected to exceed a certain clinical threshold, plays a role in this effort. However, the LR framework, and more generally, data-driven subgroup analyses, often fail to account for uncertainty in the estimation of…

指数加权目标与指数族：滤波、预测和平滑AI 解读

We propose using a discounted version of a convex combination of the log-likelihood with the corresponding expected log-likelihood such that when they are maximized they yield a filter, predictor and smoother for time series. This paper then focuses on working out the implications of this in the case of the canonical exponential family. The results are simple exact filters, predictors and smoothers with linear recursions. A theory for these models is developed and the models…

结构动态模型的目标优化识别方案AI 解读

We take a new perspective on identification in structural dynamic models: rather than imposing restrictions alone, we optimize an objective. While definitive structural identification ultimately requires exogenous economic insight, a weighted correlation-maximizing objective yields an Order- and Scale-Invariant Scheme (OASIS) that selects the orthogonal rotation most aligned with designated target variables. In traditional SVARs, these targets are the reduced-form…

通过正则化最优传输推断部分识别矩模型AI 解读

Many statistical and econometric problems involve parameters defined by moments of a joint distribution when only marginal distributions are observed, leading naturally to partial identification. We develop a methodology for identification, estimation, and inference in the corresponding partially identified GMM model. We characterize the sharp identified set for the parameter of interest via a support-function/optimal-transport (OT) representation. To estimate the identified…

随机对照试验中 AIPW 估计器 Wald 区间覆盖率的模型无关界AI 解读

Nonparametric estimators, such as the augmented inverse probability weighted (AIPW) estimator, have become increasingly popular in causal inference. Numerous nonparametric estimators have been proposed, but they are all asymptotically normal with the same asymptotic variance under similar conditions, leaving little guidance for practitioners to choose an estimator. In this paper, I focus on another important perspective of their asymptotic behaviors beyond asymptotic…

存在单位间干扰时的低秩协变量平衡估计AI 解读

A key methodological challenge in observational studies with interference between units is twofold: (1) each unit's outcome may depend on many others' treatments, and (2) treatment assignments may exhibit complex dependencies across units. We develop a general statistical framework for constructing robust causal effect estimators to address these challenges. We first show that, without restricting the patterns of interference, the standard inverse probability weighting (IPW)…

三维面板与网络数据固定效应估计的去偏推断AI 解读

Inference for fixed effects estimators is often unreliable due to Nickell- and incidental parameter biases. While these issues are well understood for classical two-dimensional panels, little is known about three-dimensional panel structures (e.g., sender x receiver x time). We develop inferential theory for a broad class of linear and nonlinear fixed effects M-estimators in this setting, covering bipartite, directed, and undirected network panel data, multiple…

条件异方差时间序列模型参数变化的稳健检验AI 解读

Structural changes and outliers often coexist, complicating statistical inference. This paper addresses the problem of testing for parameter changes in conditionally heteroscedastic time series models, particularly in the presence of outliers. To mitigate the impact of outliers, we introduce a two-step procedure comprising robust estimation and residual truncation. Based on this procedure, we propose a residual-based robust CUSUM test and its self-normalized counterpart. We…

动态阈值设计中的非参数因果推断AI 解读

We consider causal inference in dynamic settings where treatment is assigned by thresholding a state variable that can change over time. There is a large literature on regression-discontinuity methods building on the fact that, in the static setting, treatment assignment via threshold crossing induces a quasi-experimental design that enables pragmatic causal inference. But dynamic settings involve challenges not present in the static setting, e.g., past treatments may affect…

整群随机试验中依从效应与网络因果效应的识别和有效估计AI 解读

Treatment noncompliance is pervasive in infectious disease cluster-randomized trials. Although all individuals within a cluster are assigned the same treatment condition, the treatment uptake status may vary across individuals due to noncompliance. We propose a semiparametric framework to evaluate the individual compliance effect and network assignment effect within principal stratum exhibiting different patterns of noncompliance. The individual compliance effect captures…

条件独立性检验在实践中的困难AI 解读

Tests of conditional independence (CI) underpin a number of important problems in machine learning and statistics, from causal discovery to evaluation of predictor fairness and out-of-distribution robustness. Shah and Peters (2020) showed that, contrary to the unconditional case, no universally finite-sample valid test can ever achieve nontrivial power. While informative, this result (based on "hiding" dependence) does not seem to explain the frequent practical failures…

与利润目标一致的条件平均处理效应估计：协调政策学习与推断AI 解读

We propose a framework that aligns Conditional Average Treatment Effect (CATE) estimation with profit maximization. Our method recognizes that, for customers with extreme treatment effects, additional estimation accuracy is unlikely to change the recommended actions. In contrast, accuracy is critical near the decision boundary, where treatment effects are close to treatment costs. Our approach optimizes a novel objective function that concentrates learning capacity along…

重回反馈：面板数据中的动态与异质性AI 解读

Many popular estimation methods in panel data rely on the assumption that the covariates of interest are strictly exogenous. However, this assumption is empirically restrictive in a wide range of settings. In this paper I argue that credible empirical work requires meaningfully relaxing strict exogeneity assumptions. Econometricians have developed methods that allow for sequential exogeneity, which in contrast with strict exogeneity allows for the presence of feedback from…

带约束的经验福利最大化AI 解读

Empirical Welfare Maximization (EWM) is a framework that can be used to select welfare program eligibility policies based on data. This paper extends EWM by allowing for uncertainty in estimating the budget needed to implement the selected policy, in addition to its welfare. Due to the additional estimation error, I show there exist no rules that achieve the highest welfare possible while satisfying a budget constraint uniformly over a wide range of DGPs. This differs from…

收益部分识别时的最优决策规则AI 解读

We derive asymptotically optimal statistical decision rules for discrete choice problems when payoffs depend on a partially-identified parameter $θ$ and the decision maker can use a point-identified parameter $μ$ to deduce restrictions on $θ$. Examples include treatment choice under partial identification and pricing with rich unobserved heterogeneity. Our notion of optimality combines a minimax approach to handle the ambiguity from partial identification of $θ$ given $μ$ wit…

双重差分估计中的处理前趋势等价性检验AI 解读

The plausibility of the ``parallel trends assumption'' in Difference-in-Differences estimation is usually assessed by a test of the null hypothesis that the difference between the average outcomes of both groups is constant over time before the treatment. However, failure to reject the null hypothesis does not imply the absence of differences in time trends between both groups. We provide equivalence tests that allow researchers to find evidence in favor of the parallel…

混合预测变量与响应变量的正则化降秩回归AI 解读

In this paper, we introduce the Generalized Mixed Regularized Reduced Rank Regression model (GMR4), an extension of the GMR3 model designed to improve performance in high-dimensional settings. GMR3 is a regression method for a mix of numeric, binary and ordinal response variables, while also allowing for mixed-type predictors through optimal scaling. GMR4 extends this approach by incorporating regularization techniques, such as Ridge, Lasso, Group Lasso, or any combination…