每日简报

结合实验与观察数据识别和估计长期因果效应AI 解读

We study identifying and estimating the causal effect of a treatment variable on a long-term outcome using data from an observational and an experimental domain. The observational data are subject to unobserved confounding. Furthermore, subjects in the experiment are only followed for a short period; thus, long-term effects are unobserved, though short-term effects are available. Consequently, neither data source alone suffices for causal inference on the long-term outcome,…

用于个性化与透明证据综合的加权方法AI 解读

Over the past few decades, statistical methods for causal inference have made impressive strides, enabling progress across a range of scientific fields. However, much of this methodological development has been confined to individual studies, limiting its ability to draw more generalizable conclusions. Achieving a thorough understanding of cause and effect typically relies on the integration, reconciliation, and synthesis from diverse study designs and multiple data sources.…

强化学习数据收集后的统计推断AI 解读

We study estimation and inference using data collected by reinforcement learning (RL) algorithms. These algorithms adaptively experiment by interacting with individual units over multiple stages, updating their strategies based on past outcomes. Our goal is to evaluate a counterfactual policy after data collection and estimate structural parameters, such as dynamic treatment effects, that support credit assignment and quantify the impact of early actions on final outcomes.…

准确估计因果效应时的超参数调优挑战AI 解读

ML is playing an increasingly crucial role in estimating causal effects of treatments on outcomes from observational data. Many ML methods (`causal estimators') have been proposed for this task. All of these methods, as with any ML approach, require extensive hyperparameter tuning. For non-causal predictive tasks, there is a consensus on the choice of tuning metrics (e.g. mean squared error), making it simple to compare models. However, for causal inference tasks, such a…

零膨胀单细胞 RNA 测序数据的共同中介统计框架AI 解读

Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of cellular heterogeneity, enabling detailed molecular profiling at the individual cell level. However, integrating high-dimensional single-cell data into causal mediation analysis remains challenging due to zero inflation and complex mediator structures. We propose a novel mediation framework leveraging zero-inflated negative binomial models to characterize cell-level mediator distributions and beta…

聚合树AI 解读

Uncovering the heterogeneous effects of particular policies or "treatments" is a key concern for researchers and policymakers. A common approach is to report average treatment effects across subgroups based on observable covariates. However, the choice of subgroups is crucial as it poses the risk of $p$-hacking and requires balancing interpretability with granularity. This paper proposes a nonparametric approach to construct heterogeneous subgroups. The approach enables a…

生存函数的因果推断AI 解读

In this expository paper, we consider the problem of causal inference and efficient estimation for the counterfactual survivor function. This problem has previously been considered in the literature in several papers, each relying on the imposition of conditions meant to identify the desired estimand from the observed data. These conditions, generally referred to as either implying or satisfying coarsening at random, are inconsistently imposed across this literature and, in…

二元结果工具变量模型的崩溃分析AI 解读

This paper studies the partial identification of treatment effects in Instrumental Variables (IV) settings with binary outcomes under violations of independence. I derive the identified sets for the treatment parameters of interest in the setting, as well as breakdown values for conclusions regarding the true treatment effects. I derive $\sqrt{N}$-consistent nonparametric estimators for the bounds of treatment effects and for breakdown values. These results can be used to…

大量弱无效工具变量下右删失结局的半参数因果推断AI 解读

We propose a semiparametric framework for causal inference with right-censored survival outcomes and many weak invalid instruments, motivated by Mendelian randomization in biobank studies where classical methods may fail. We adopt an accelerated failure time model and construct a moment condition based on augmented inverse probability of censoring weighting, incorporating both uncensored and censored observations. Under a heteroscedasticity-based condition on the treatment…

非参数因果图模型中时变处理效应估计的高效调整集AI 解读

Criteria for identifying optimal adjustment sets yielding consistent estimation with minimal asymptotic variance of average treatment effects in parametric and nonparametric models have recently been established. In a single treatment time point setting, it has been shown that the optimal adjustment set can be identified based on a causal directed acyclic graph alone. In a time-dependent treatment setting, previous work has established graphical rules to compare the…

引用网络的双向共因子分析AI 解读

One compelling use of citation networks is to characterize papers by their relationships to the surrounding literature. We propose a method to characterize papers by embedding them into two distinct "co-factor" spaces: one describing how papers send citations, and the other describing how papers receive citations. This approach presents several challenges. First, older documents cannot cite newer documents, and thus it is not clear that co-factors are even identifiable. We…

公共资金边际价值的统计推断AI 解读

Economists often estimate causal effects of policies on multiple outcomes and summarize them into scalar measures of cost-effectiveness or welfare, such as the Marginal Value of Public Funds (MVPF). In many settings, microdata underlying these estimates are unavailable, leaving researchers with only published estimates and their standard errors. We develop tools for valid inference on functions of causal effects, such as the MVPF, when the correlation structure is unknown.…

异质地点间因果效应的迁移估计AI 解读

We consider the problem of extrapolating treatment effects across heterogeneous populations (``sites"/``contexts"). We consider an idealized scenario in which the researcher observes cross-sectional data for a large number of units across several ``experimental" sites in which an intervention has already been implemented to a new ``target" site for which a baseline survey of unit-specific, pre-treatment outcomes and relevant attributes is available. Our approach treats the…

利用外部对照改进处理效应估计的自适应数据借用AI 解读

Randomized controlled trials (RCTs) often exhibit limited inferential efficiency in estimating treatment effects due to small sample sizes. In recent years, the combination of external controls has gained increasing attention as a means of improving the efficiency of RCTs. However, external controls are not always comparable to RCTs, and direct borrowing without careful evaluation can introduce substantial bias and reduce the efficiency of treatment effect estimation. In…