Randomization inference for stepped-wedge designs with noncompliance with application to a palliative care pragmatic trial
存在不依从时阶梯楔形设计的随机化推断:姑息治疗试验应用
While palliative care is increasingly commonly delivered to hospitalized patients with serious illnesses, few studies have estimated its causal effects. Courtright et al. (2016) adopted a stepped-wedge cluster-randomized design to assess the effect of palliative care on a patient-centered outcome. The randomized intervention was a nudge to administer palliative care but did not guarantee receipt of palliative care, resulting in noncompliance. A subsequent analysis using…