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本期 41 篇
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arXiv · 本期首次发布

What is estimated in cluster randomized crossover trials with informative sizes? -- A survey of estimands and common estimators

信息性规模下的整群随机交叉试验究竟估计什么:目标量与常用估计量综述

In the analysis of cluster randomized trials (CRTs), previous work has defined two meaningful estimands: the individual-average treatment effect (iATE) and cluster-average treatment effect (cATE) estimand, to address individual and cluster-level hypotheses. In multi-period CRT designs, such as the cluster randomized crossover (CRXO) trial, additional weighted average treatment effect estimands help fully reflect the longitudinal nature of these trial designs, namely the…

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Causal Identification in Time Series Models

时间序列模型中的因果识别

In this paper, we analyze the applicability of the Causal Identification algorithm to causal time series graphs with latent confounders. Since these graphs extend over infinitely many time steps, deciding whether causal effects across arbitrary time intervals are identifiable appears to require computation on graph segments of unbounded size. Even for deciding the identifiability of intervention effects on variables that are close in time, no bound is known on how many time…

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The Estimation of Continual Causal Effect for Dataset Shifting Streams

数据分布变化流中的持续因果效应估计

Causal effect estimation has been widely used in marketing optimization. The framework of an uplift model followed by a constrained optimization algorithm is popular in practice. To enhance performance in the online environment, the framework needs to be improved to address the complexities caused by temporal dataset shift. This paper focuses on capturing the dataset shift from user behavior and domain distribution changing over time. We propose an Incremental Causal Effect…

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Representation Learning Preserving Ignorability and Covariate Matching for Treatment Effects

保持可忽略性并实现协变量匹配的处理效应表示学习

Estimating treatment effects from observational data is challenging due to two main reasons: (a) hidden confounding, and (b) covariate mismatch (control and treatment groups not having identical distributions). Long lines of works exist that address only either of these issues. To address the former, conventional techniques that require detailed knowledge in the form of causal graphs have been proposed. For the latter, covariate matching and importance weighting methods have…

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Multi-Domain Causal Discovery in Bijective Causal Models

双射因果模型中的多域因果发现

We consider the problem of causal discovery (a.k.a., causal structure learning) in a multi-domain setting. We assume that the causal functions are invariant across the domains, while the distribution of the exogenous noise may vary. Under causal sufficiency (i.e., no confounders exist), we show that the causal diagram can be discovered under less restrictive functional assumptions compared to previous work. What enables causal discovery in this setting is bijective…

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Hurdle Network Model With Latent Dynamic Shrinkage For Enhanced Edge Prediction in Zero-Inflated Directed Network Time Series

潜在动态收缩障碍网络模型:零膨胀有向网络时间序列的边预测

This article aims to model international trade relationships among 29 countries in the apparel industry between 1994 and 2013. Bilateral trade flows can be represented as a directed network, where nodes correspond to countries and directed edges indicate trade flows (i.e., whether one country exported to another in a given year). Additionally, node (e.g., GDP) and edge-specific (e.g., labor provision) covariates are also available. The study focuses on two key challenges:…

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Real-time Program Evaluation using Anytime-valid Rank Tests

利用随时有效秩检验开展实时项目评估

Counterfactual mean estimators such as difference-in-differences and synthetic control have grown into workhorse tools for program evaluation. Inference for these estimators is well-developed in settings where all post-treatment data is available at the time of analysis. However, in settings where data arrives sequentially, these tests do not permit real-time inference, as they require a pre-specified sample size T. We introduce real-time inference for program evaluation…

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Convergence rate for Nearest Neighbour matching: geometry of the domain and higher-order regularity

最近邻匹配的收敛率:支持域几何与高阶正则性

Estimating some mathematical expectations from partially observed data and in particular missing outcomes is a central problem encountered in numerous fields such as transfer learning, counterfactual analysis or causal inference. Matching estimators, estimators based on k-nearest neighbours, are widely used in this context. It is known that the variance of such estimators can converge to zero at a parametric rate, but their bias can have a slower rate when the dimension of…

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Q-Learning with Clustered-SMART (cSMART) Data: Examining Moderators in the Construction of Clustered Adaptive Interventions

聚类序贯多次随机试验的 Q 学习:自适应干预中的效应调节变量

A clustered adaptive intervention (cAI) is a pre-specified sequence of decision rules that guides practitioners on how best - and based on which measures - to tailor cluster-level intervention to improve outcomes at the level of individuals within the clusters. A clustered sequential multiple assignment randomized trial (cSMART) is a type of trial that is used to inform the empirical development of a cAI. The most common type of secondary aim in a cSMART focuses on assessing…

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Overview and practical recommendations on using Shapley Values for identifying predictive biomarkers via CATE modeling

通过 CATE 建模与 Shapley 值识别预测性生物标志物:概述与实践建议

In recent years, two parallel research trends have emerged in machine learning, yet their intersections remain largely unexplored. On one hand, there has been a significant increase in literature focused on Individual Treatment Effect (ITE) modeling, particularly targeting the Conditional Average Treatment Effect (CATE) using meta-learner techniques. These approaches often aim to identify causal effects from observational data. On the other hand, the field of Explainable…

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Extended Fiducial Inference for Individual Treatment Effects via Deep Neural Networks

通过深度神经网络开展个体治疗效应的扩展信赖推断

Individual treatment effect estimation has gained significant attention in recent data science literature. This work introduces the Double Neural Network (Double-NN) method to address this problem within the framework of extended fiducial inference (EFI). In the proposed method, deep neural networks are used to model the treatment and control effect functions, while an additional neural network is employed to estimate their parameters. The universal approximation capability…

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Adaptive sample splitting for randomization tests

随机化检验的自适应样本分割

Randomization tests are widely used to generate finite-sample valid $p$-values for causal inference on experimental data. However, when applied to subgroup analysis, these tests may lack power due to small subgroup sizes. Incorporating a shared estimator of the conditional average treatment effect (CATE) can substantially improve power across subgroups but requires sample splitting to preserve validity. To this end, we quantify each unit's contribution to estimation and…

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Inference with few treated units

少量处理单位情形下的统计推断

In many causal inference applications, only one or a few units (or clusters of units) are treated. An important challenge in such settings is that standard inference methods relying on asymptotic theory may be unreliable, even with large total sample sizes. This survey reviews and categorizes inference methods designed to accommodate few treated units, considering cross-sectional and panel data methods. We discuss trade-offs and connections between different approaches. In…

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Design-Based Inference under Random Potential Outcomes

随机潜在结果下的基于设计的推断

We study whether mechanism-level causal estimands, defined as expectations over latent stochastic environments, can be consistently recovered from a single realised randomised experiment. Identification alone does not guarantee recoverability. The target estimand averages over latent environments, whereas a single experiment provides only one realisation of such an environment. We show that suitably sparse local dependence induces an ergodic-type property under which…

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Rerandomization for covariate balance mitigates $p$-hacking caused by strategically selecting covariates in regression adjustment

协变量平衡的再随机化如何缓解回归调整中的显著性操纵

Rerandomization enforces covariate balance across treatment groups in the design stage of experiments. Despite its intuitive appeal, its theoretical justification remains unsatisfying because its benefits of improving efficiency for estimating the average treatment effect diminish if we use regression adjustment in the analysis stage. To strengthen the theory of rerandomization, we show that it mitigates false discoveries resulting from $p$-hacking caused by strategically…

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Robust Estimation and Inference in Hybrid Controlled Trials for Binary Outcomes: A Case Study on Non-Small Cell Lung Cancer

二元结果混合对照试验的稳健估计与推断:非小细胞肺癌案例

Hybrid controlled trials (HCTs), which augment randomized controlled trials (RCTs) with external controls (ECs), are increasingly receiving attention as a way to address limited power, slow accrual, and ethical concerns in clinical research. However, borrowing from ECs raises critical statistical challenges in estimation and inference, especially for binary outcomes where hidden bias is harder to detect and estimands such as risk difference, risk ratio, and odds ratio are of…

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Inference for max-linear Bayesian networks with noise

带噪声最大线性贝叶斯网络的推断

Max-Linear Bayesian Networks (MLBNs) provide a powerful framework for causal inference in extreme-value settings; we consider MLBNs with noise parameters with a given topology in terms of the max-plus algebra by taking its logarithm. Then, we show that an estimator of a parameter for each edge in a directed acyclic graph (DAG) is distributed normally. We end this paper with computational experiments with the expectation and maximization (EM) algorithm and quadratic…

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Reinforcement Learning with Continuous Actions Under Unmeasured Confounding

未测混杂下连续动作空间的强化学习

This paper addresses the challenge of offline policy learning in reinforcement learning with continuous action spaces when unmeasured confounders are present. While most existing research focuses on policy evaluation within partially observable Markov decision processes (POMDPs) and assumes discrete action spaces, we advance this field by establishing a novel identification result to enable the nonparametric estimation of policy value for a given target policy under an…

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Statistical Learning for Heterogeneous Treatment Effects: Pretraining, Prognosis, and Prediction

异质性处理效应的统计学习:预训练、预后与预测

Robust estimation of heterogeneous treatment effects is a fundamental challenge for optimal decision-making in domains ranging from personalized medicine to educational policy. In recent years, predictive machine learning has emerged as a valuable toolbox for causal estimation, enabling more flexible effect estimation. However, accurately estimating conditional average treatment effects (CATE) remains a major challenge, particularly in the presence of many covariates. In…

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Pre-Training Estimators for Structural Models: Application to Consumer Search

结构模型的预训练估计器:消费者搜寻应用

We develop pre-trained estimators for structural econometric models. The estimator uses a neural net to recognize the structural model's parameter from data patterns. Once trained, the estimator can be shared and applied to different datasets at negligible cost and effort. Under sufficient training, the estimator converges to the Bayesian posterior given the data patterns. As an illustration, we construct a pretrained estimator for a sequential search model (available at…

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Doubly robust augmented weighting estimators for the analysis of externally controlled single-arm trials and unanchored indirect treatment comparisons

外部对照单臂试验与非锚定间接治疗比较的双重稳健增广加权估计

Externally controlled single-arm trials are critical to assess treatment efficacy across therapeutic indications for which randomized controlled trials are not feasible. A closely-related research design, the unanchored indirect treatment comparison, is often required for disconnected treatment networks in health technology assessment. We present a unified causal inference framework for both research designs. We develop a novel estimator that augments a popular weighting…

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A Unifying Framework for Robust and Efficient Inference with Unstructured Data

非结构化数据稳健与有效推断的统一框架

To analyze unstructured data (text, images, audio, video), economists typically first extract low-dimensional structured features with a neural network. Neural networks do not make generically unbiased predictions, and biases will propagate to estimators that use their predictions. While structured variables extracted from unstructured data have traditionally been treated as proxies - implicitly accepting arbitrary measurement error - this poses various challenges in an era…

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Spatial vertical regression for spatial panel data: Evaluating the effect of the Florentine tramway's first line on commercial vitality

空间面板数据的空间纵向回归:佛罗伦萨首条电车线对商业活力的影响

Synthetic control methods are commonly used in panel data settings to evaluate the effect of an intervention. In many of these cases, the treated and control units correspond to spatial units such as regions or neighborhoods. Our approach addresses the challenge of understanding how an intervention applied at specific locations influences the surrounding area. Traditional synthetic control applications may struggle with defining the effective area of impact, the extent of…

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The Promises of Multiple Experiments: Identifying Joint Distribution of Potential Outcomes

多个实验的潜力:识别潜在结果的联合分布

Typical causal effects are defined based on the marginal distribution of potential outcomes. However, many real-world applications require causal estimands involving the joint distribution of potential outcomes to enable more nuanced treatment evaluation and selection. In this article, we propose a novel framework for identifying and estimating the joint distribution of potential outcomes using multiple experimental datasets. We introduce the assumption of transportability…

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